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Luminescence and also Stability Enhancement regarding Inorganic Perovskite Nanocrystals by means of Selective Surface Ligand Binding.
The objective of this study was to investigate the change in near visual function after the administration of oral silodosin to patients with lower urinary tract symptom (LUTS).

This prospective study included treatment naïve patients who were scheduled to start treatment with silodosin for LUTS. A comprehensive ophthalmological evaluation including the near vision and the automated pupillometry was performed at baseline and after 3 months of silodosin treatment. For subjective assessment of near visual ability and satisfaction, a Near Activity Visual Questionnaire-10 (NAVQ-10) was also used at the same time (higher scores indicating worse quality).

Of 23 patients enrolled in this study, 15 continued with silodosin (8mg once daily) treatment for 3 months and completed a follow-up evaluation. The mean age of participants was 60.4±8.4 years. Distant visual acuity and spherical error were unchanged after silodosin treatment. However, near vision acuity (logMAR) was improved after treatment (right, 0.47±0.3ision.
Benign prostatic hyperplasia (BPH) is associated with lower urinary tract symptoms and negatively affects the quality of life. We aimed to investigate the treatment pattern of BPH in South Korea.

Information on treatment modalities and diagnoses of BPH was obtained from the Health Insurance Review and Assessment Service-Aged Patient Sample. Data on BPH patients aged >60 years from 2012 to 2016 were obtained. We surveyed the treatment pattern of BPH, including the types of drugs used and surgeries performed, according to the type of institution.

In this study, 18,260-24,657 BPH patients treated between 2012 and 2016 were included. The number of patients showed an increasing pattern, and drug therapy was the major treatment method used for BPH (98.77%). Moreover, the pattern of increased pharmacotherapy use for BPH was reinforced by the increasing number of patients. Prescription of α-blockers only was dominant in this cohort (45.7%). Transurethral resection of the prostate (TURP) was the most commonly used surgical treatment for BPH (53.6%), but it showed a decreasing pattern over time. In contrast, holmium laser enucleation of the prostate (HoLEP) showed an increase from 19.4% to 39.7%.

The most common treatment for BPH was drug therapy, predominantly only α-blocker therapy. The surgical treatment trend has changed from TURP to HoLEP.
The most common treatment for BPH was drug therapy, predominantly only α-blocker therapy. The surgical treatment trend has changed from TURP to HoLEP.
Transcutaneous tibial nerve stimulation (TTNS) has proven itself a valuable treatment option for various lower urinary tract conditions like the overactive bladder syndrome or neurogenic detrusor overactivity. The aim of this study was to investigate acute changes in urodynamic parameters due to bilateral TTNS.

51 patients (18 - 87 years; 61 % female) with various lower urinary tract symptoms were enrolled in this study. They were single-blinded and randomly assigned to receive simultaneous-bilateral TTNS either during their first urodynamic examination, followed by a second round under the influence of a placebo stimulation technique, or vice versa.

For subjects without signs of anatomical pathologies filling volume at the first desire to void (FDV) increased significantly by 54 ml (IQR 26 to 81; p < 0.01) under the influence of TTNS compared to placebo. Their maximum cystometric capacity increased by 41 ml (IQR 10 to 65; p = 0.02). The median micturition volume of patients with pathological amounts of post-void residual (>100 ml) increased by 76 ml compared to patients without urinary retention (IQR 6 to 166; p = 0.03).

Compared to placebo, simultaneous-bilateral TTNS showed significant improvements of bladder functioning like delayed FDV, increased maximum cystometric capacity and reduced urinary retention. Patients with signs of anatomical pathologies do not seem to benefit from TTNS. Further studies need to be conducted to compare the effectiveness of bilateral to unilateral TTNS.
Compared to placebo, simultaneous-bilateral TTNS showed significant improvements of bladder functioning like delayed FDV, increased maximum cystometric capacity and reduced urinary retention. Patients with signs of anatomical pathologies do not seem to benefit from TTNS. Further studies need to be conducted to compare the effectiveness of bilateral to unilateral TTNS.
To investigate the video-urodynamic and pelvic floor electrophysiological characteristics in patients with traumatic spinal cord injury.

This retrospective reviewed the clinical records, urodynamic and pelvic floor electrophysiological data of 647 patients with traumatic spinal cord injury (SCI) and out of spinal shock. Patients were classified based on American Spinal Injury Association (ASIA) Impairment Scale and urodynamic findings.

Of the 647 patients, detrusor overactivity (DO) with or without detrusor sphincter dyssynergia (DSD) was found in 79.5%, 61%, 35.2%, 35%, and 19.2% of patients with cervical, thoracic (T1-9), thoracic (T10-12), lumbar, and conical cauda injury, respectively. Other patients manifested detrusor areflexia (DA). Selleck Omipalisib Patients with DO and/or DSD had a longer duration of SCI at each injury level than patients with DA. In suprasacral injury patients with DA, 63.0% (58/92) had a normal bulbocavernosus reflex (BCR) response. Compared with patients without bladder sensation, bladder capacity during urine leakage was far higher in those with bladder sensation. The manifestation of BCR and somatosensory-evoked potential (SEP) was associated with the level of injury.

This study showed a significant correlation between the level of SCI and video-urodynamic findings, but clinical examination cannot by predict bladder function; urodynamic testing is also necessary. In addition, the role of BCR and SEP for guiding bladder management is limited. Moreover, bladder sensation is important for urinary control in patients with traumatic SCI.
This study showed a significant correlation between the level of SCI and video-urodynamic findings, but clinical examination cannot by predict bladder function; urodynamic testing is also necessary. In addition, the role of BCR and SEP for guiding bladder management is limited. Moreover, bladder sensation is important for urinary control in patients with traumatic SCI.
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