Notes

Cancer malignancy immunotherapy: A comprehensive assessment of their settings regarding software.
05). Moreover, eighteen important variables, whose average importance scores were highest and whose error rates were lowest, were selected by random forest method. Data from multivariate logistic regression showed that MS in SLE was related with BMI, diastolic blood pressure, systolic blood pressure, fasting blood glucose, arthritis, urea, triglycerides, high-density lipoprotein, and white blood cells.

MS in SLE was closely related to BMI, blood pressure, blood sugar, blood lipids, arthritis, white blood cells, and urea. Targeted prevention and conclusion measures for the risk factors should be taken as early as possible.
MS in SLE was closely related to BMI, blood pressure, blood sugar, blood lipids, arthritis, white blood cells, and urea. Targeted prevention and conclusion measures for the risk factors should be taken as early as possible.
To evaluate the Effectiveness of Pre-operative Respiratory Muscle Training versus Conventional Treatment for Improving post-operative pulmonary health after Coronary Artery Bypass Graft Surgery (CABG).

A Prospective Randomized clinical trial was performed on sixty patients who underwent elective CABG at Faisalabad Institute of Cardiology. At the time of admission all patients were subjected to 6-minutes' walk test (6MWT) as baseline. The subjects were then divided into two groups. The Group-I was subjected to respiratory muscle training whereas the Group-2 received the routine preoperative care. The 6-minute walk test (6MWT) was then repeated a day before surgery (pre-operative) and before discharge (post-operatively). Duration of post-operative mechanical ventilation, oxygen therapy and hospital stay were also noted as outcome measures of this study.

The pre-operative and post-operative readings showed that the patients in the interventional group performed better than the control group in their 6MWT with P-value of less than 0.05. Similarly the interventional group had shorter duration of mechanical ventilation, dependence on oxygen therapy and postoperative hospital stay as compared with the control group showing P-values below 0.05.

The results showed that respiratory muscle training results in improved postoperative functional capacity and reduces of hospital stay.
The results showed that respiratory muscle training results in improved postoperative functional capacity and reduces of hospital stay.
The main objective of this study was to explore the impact of hearing impairment on psychological distress and subjective well-being in older adults with hearing impairment.

The study with cross sectional research design was conducted in three public sector hospitals of Lahore, from February 2017 to June 2017. Participants of the study were adults aged 50-90 years and with hearing impairment, selected through non-probability sampling technique. Demographic Information sheet, Kessler psychological distress scale by Kessler, Mroczek. in 1992 and Satisfaction with life scale by Diener, Emmons, Larsen, Griffin in 1985 were used for data collection. SPSS 21 was used to analyze the data.

There were 200 participants with age ranged from 53 to 89 years (M= 65.92, SD= 9.70). Eprenetapopt mouse Of the total, 100 (50%) subjects were men and 100 (50%) were women. Significant gender differences were found in psychological distress, with men reflecting more symptoms of psychological distress (p<0.01), whereas non-significant gender differences were found in case of subjective well-being (p>0.05). Moreover, psychological distress was observed as a predictor of subjective well-being (
<0.01). One-way analysis of variance revealed insignificant differences of psychological distress and subjective well-being across three levels of hearing impairment.

Early diagnosis and rehabilitation of age-related hearing loss improves the overall quality of life of older adults living with hearing impairment.
Early diagnosis and rehabilitation of age-related hearing loss improves the overall quality of life of older adults living with hearing impairment.
To determine student's perception of bedside clinical teaching and to correlate it with their performance in assessment.

This cross-sectional study of correlational survey was conducted at Services Institute of Medical Sciences in September 2019, involving students of final professional year who filled a proforma to rate their bedside teaching experience during clinical rotations using rating scale. Mean scores of items were determined with score < 3 reflecting dis-satisfaction. Mean scores were compared between high and low performing students using student's t test.

Total of 160 students participated. Physical environment domain was assigned lowest scores by students (mean 2.94±0.74) followed by teaching task by teachers (3.04±0.72), group dynamics (3.16±0.81) and patient comfort and attitude towards patient (3.87±0.60). Teaching task by teacher had maximum stems with scores < 3 needing significant improvement. Students with low academic performance were more unsatisfied with group dynamics of bedside teaching (p value 0.009), especially lack of equal opportunities of participation for every member (p value <0.000) in clinical rotations.

Small size group with adequate space for bedside training and faculty training can enhance learning experience of students. Ensuring active participation of each group member during bedside learning can improve academic performance of students.
Small size group with adequate space for bedside training and faculty training can enhance learning experience of students. Ensuring active participation of each group member during bedside learning can improve academic performance of students.
To study the clinical, biochemical and radiological features and management outcomes of patients with primary hyperparathyroidism.

This retrospective study was conducted at the Aga Khan University Hospital, Karachi, Pakistan and comprised data of patients with primary hyperparathyroidism from 2008 to 2017.

Out of 103 patients, 83(80.6%) were female. Overall mean age was 59.3±16.2 years. Musculoskeletal manifestations were seen in 60(58.3%) patients and renal manifestations in 28(27.2%). Ostieits fibrosa cystica was found in 04(3.88%) patients. Overall, Ultrasound neck and sestamibi scan localized the lesion in 66 (64.1%) and 77 (76.2%) patients respectively. Among 79 patients who underwent surgery, 67 (84.8%) patients had an adenoma, 05 (6.3%) had hyperplasia and 02(2.53%) patients had parathyroid carcinoma whereas histopathology was inconclusive in 5 (6.32%) out of the 79 surgically treated patients. Disease recurrence was seen in 13 out of 79(16.45%) patients who underwent surgery.

Primary hyperparathyroidism is associated with significant morbidity in our population.
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