Notes

Hypoxia-inducible factor-1: Regulating systems as well as substance boost cerebrovascular accident.
Radiological prediction using RECIST criteria reached an accuracy of 0.78.

These results suggest the importance of early delta radiomics and of ADC maps to predict the response to IC in sinonasal cancers.
These results suggest the importance of early delta radiomics and of ADC maps to predict the response to IC in sinonasal cancers.Bone and soft-tissue primary malignant tumors or sarcomas are a large, diverse group of mesenchymal-derived malignancies. They represent a model for intra- and intertumoral heterogeneities, making them particularly suitable for radiomics analyses. Radiomic features offer information on cancer phenotype as well as the tumor microenvironment which, combined with other pertinent data such as genomics and proteomics and correlated with outcomes data, can produce accurate, robust, evidence-based, clinical-decision support systems. Our purpose in this narrative review is to offer an overview of radiomics studies dealing with Magnetic Resonance Imaging (MRI)-based radiomics models of bone and soft-tissue sarcomas that could help distinguish different histotypes, low-grade from high-grade sarcomas, predict response to multimodality therapy, and thus better tailor patients' treatments and finally improve their survivals. Although showing promising results, interobserver segmentation variability, feature reproducibility, and model validation are three main challenges of radiomics that need to be addressed in order to translate radiomics studies to clinical applications. These efforts, together with a better knowledge and application of the "Radiomics Quality Score" and Image Biomarker Standardization Initiative reporting guidelines, could improve the quality of sarcoma radiomics studies and facilitate radiomics towards clinical translation.The present paper proposes an implementation of a hybrid hardware-software system for the visual servoing of prosthetic arms. We focus on the most critical vision analysis part of the system. The prosthetic system comprises a glass-worn eye tracker and a video camera, and the task is to recognize the object to grasp. The lightweight architecture for gaze-driven object recognition has to be implemented as a wearable device with low power consumption (less than 5.6 W). The algorithmic chain comprises gaze fixations estimation and filtering, generation of candidates, and recognition, with two backbone convolutional neural networks (CNN). The time-consuming parts of the system, such as SIFT (Scale Invariant Feature Transform) detector and the backbone CNN feature extractor, are implemented in FPGA, and a new reduction layer is introduced in the object-recognition CNN to reduce the computational burden. The proposed implementation is compatible with the real-time control of the prosthetic arm.Computer vision plays an important role in the accurate foreground detection of medical images. Diagnosing diseases in their early stages has effective life-saving potential, and this is every physician's goal. There is a positive relationship between improving image segmentation methods and precise diagnosis in medical images. This relation provides a profound indication for feature extraction in a segmented image, such that an accurate separation occurs between the foreground and the background. There are many thresholding-based segmentation methods found under the pure image processing approach. Minimum cross entropy thresholding (MCET) is one of the frequently used mean-based thresholding methods for medical image segmentation. In this paper, the aim was to boost the efficiency of MCET, based on heterogeneous mean filter approaches. The proposed model estimates an optimized mean by excluding the negative influence of noise, local outliers, and gray intensity levels; thus, obtaining new mean values for the MCET's objective function. The proposed model was examined compared to the original and related methods, using three types of medical image dataset. It was able to show accurate results based on the performance measures, using the benchmark of unsupervised and supervised evaluation.Developing Field Programmable Gate Array (FPGA)-based applications is typically a slow and multi-skilled task. https://www.selleckchem.com/products/adaptaquin.html Research in tools to support application development has gradually reached a higher level. This paper describes an approach which aims to further raise the level at which an application developer works in developing FPGA-based implementations of image and video processing applications. The starting concept is a system of streamed soft coprocessors. We present a set of soft coprocessors which implement some of the key abstractions of Image Algebra. Our soft coprocessors are designed for easy chaining, and allow users to describe their application as a dataflow graph. A prototype implementation of a development environment, called SCoPeS, is presented. An application can be modified even during execution without requiring re-synthesis. The paper concludes with performance and resource utilization results for different implementations of a sample algorithm. We conclude that the soft coprocessor approach has the potential to deliver better performance than the soft processor approach, and can improve programmability over dedicated HDL cores for domain-specific applications while achieving competitive real time performance and utilization.Advances in computing and AI technology have promoted the development of connected health systems, indirectly influencing approaches to cataract treatment. In addition, thanks to the development of methods for cataract detection and grading using different imaging modalities, ophthalmologists can make diagnoses with significant objectivity. This paper aims to review the development and limitations of published methods for cataract detection and grading using different imaging modalities. Over the years, the proposed methods have shown significant improvement and reasonable effort towards automated cataract detection and grading systems that utilise various imaging modalities, such as optical coherence tomography (OCT), fundus, and slit-lamp images. However, more robust and fully automated cataract detection and grading systems are still needed. In addition, imaging modalities such as fundus, slit-lamps, and OCT images require medical equipment that is expensive and not portable. Therefore, the use of digital images from a smartphone as the future of cataract screening tools could be a practical and helpful solution for ophthalmologists, especially in rural areas with limited healthcare facilities.This paper presents a photometric stereo (PS) method based on the dichromatic reflectance model (DRM) using colour images. The proposed method estimates surface orientations for surfaces with non-Lambertian reflectance using diffuse-specular separation and contains two steps. The first step, referred to as diffuse-specular separation, initialises surface orientations in a specular invariant colour subspace and further separates the diffuse and specular components in the RGB space. In the second step, the surface orientations are refined by first initialising specular parameters via solving a log-linear regression problem owing to the separation and then fitting the DRM using Levenburg-Marquardt algorithm. Since reliable information from diffuse reflection free from specularities is adopted in the initialisations, the proposed method is robust and feasible with less observations. At pixels where dense non-Lambertian reflectances appear, signals from specularities are exploited to refine the surface orientations and the additionally acquired specular parameters are potentially valuable for more applications, such as digital relighting. The effectiveness of the newly proposed surface normal refinement step was evaluated and the accuracy in estimating surface orientations was enhanced around 30% on average by including this step. The proposed method was also proven effective in an experiment using synthetic input images comprised of twenty-four different reflectances of dielectric materals. A comparison with nine other PS methods on five representative datasets further prove the validity of the proposed method.The Bologna Archaeological Museum, in cooperation with prestigious Italian universities, institutions, and independent scholars, recently began a vast investigation programme on a group of Egyptian coffins of Theban provenance dating to the first millennium BC, primarily the 25th-26th Dynasty (c. 746-525 BC). Herein, we present the results of the multidisciplinary investigation carried out on one of these coffins before its restoration intervention the anthropoid wooden coffin of Un-Montu (Inv. MCABo EG1960). The integration of radiocarbon dating, wood species identification, and CT imaging enabled a deep understanding of the coffin's wooden structure. In particular, we discuss the results of the tomographic investigation performed in situ. The use of a transportable X-ray facility largely reduced the risks associated with the transfer of the large object (1.80 cm tall) out of the museum without compromising image quality. Thanks to the 3D tomographic imaging, the coffin revealed the secrets of its construction technique, from the rational use of wood to the employment of canvas (incamottatura), from the use of dowels to the assembly procedure.Transfer learning from natural images is used in deep neural networks (DNNs) for medical image classification to achieve a computer-aided clinical diagnosis. Although the adversarial vulnerability of DNNs hinders practical applications owing to the high stakes of diagnosis, adversarial attacks are expected to be limited because training datasets (medical images), which are often required for adversarial attacks, are generally unavailable in terms of security and privacy preservation. Nevertheless, in this study, we demonstrated that adversarial attacks are also possible using natural images for medical DNN models with transfer learning, even if such medical images are unavailable; in particular, we showed that universal adversarial perturbations (UAPs) can also be generated from natural images. UAPs from natural images are useful for both non-targeted and targeted attacks. The performance of UAPs from natural images was significantly higher than that of random controls. The use of transfer learning causes a security hole, which decreases the reliability and safety of computer-based disease diagnosis. Model training from random initialization reduced the performance of UAPs from natural images; however, it did not completely avoid vulnerability to UAPs. The vulnerability of UAPs to natural images is expected to become a significant security threat.Holotomography is an extension of computed tomography where samples with low X-ray absorption can be investigated with higher contrast. In order to achieve this, the imaging system must yield an optical resolution of a few micrometers or less, which reduces the measurement area (field of view = FOV) to a few mm at most. If the sample size, however, exceeds the field of view (called local tomography or region of interest = ROI CT), filter problems arise during the CT reconstruction and phase retrieval in holotomography. In this paper, we will first investigate the practical impact of these filter problems and discuss approximate solutions. Secondly, we will investigate the effectiveness of a technique we call "multiscalar holotomography", where, in addition to the ROI CT, a lower resolution non-ROI CT measurement is recorded. This is used to avoid the filter problems while simultaneously reconstructing a larger part of the sample, albeit with a lower resolution in the additional area.
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