Notes

Is there a position for immune-enhancing therapies for acutely ill sufferers together with coronavirus ailment 2019?
The prevalence of musculoskeletal (MSK) symptoms in radiographers is high, similar to other healthcare occupations that involve high levels of physical exertion (e.g. patient handling; grasping and moving equipment). Reports of interventions to reduce MSK discomfort in radiographers are limited. A participatory approach was used to investigate daily challenges, needs, and opportunities for developing interventions to address exposures to many of the risk factors that contribute to MSK symptoms in radiographers. In this paper, we present the expressed needs of experienced radiographers (including assistance with patient handling, security, supportive design of equipment and work spaces), along with their evaluations of several intervention concepts intended to address some of those needs. We also report results from tests of three prototype interventions stemming from this participatory process that demonstrate the potential for new engineering control concepts to reduce the physical effort associated with some of the most common tasks radiographers perform. Being able to anticipate upcoming motion is known to potentially mitigate sickness resulting from provocative motion. We investigated whether auditory cues could increase anticipation and subsequently reduce motion sickness. Participants (N = 20) were exposed on a sled on a rail track to two 15-min conditions. selleck products Both were identical in terms of motion, being composed of the same repeated 9 m fore-aft displacements, with a semi-random timing of pauses and direction. The auditory cues were either 1) informative on the timing and direction of the upcoming motion, or 2) non-informative. Illness ratings were recorded at 1-min intervals using a 11-point scale. After exposure, average illness ratings were significantly lower for the condition that contained informative auditory cues, as compared to the condition without informative cues. This knowledge, i.e. that auditory signals can improve anticipation to motion, could be of importance in reducing carsickness in domains such as that of autonomous vehicles. Many studies of ballpoint pens have been conducted. However, those studies have not considered the emotional factors that can enhance user experience. Styluses resemble ballpoint pens in many ways, which are widely available in a variety of styles. Therefore, in the present study, we explored the physical and emotional attributes that improve user satisfaction with typical ballpoint pens, with the goal of also understanding what factors might be important for stylus design. First, 14 emotional factors associated with the pens were derived. Second, 16 different types of ball-point pens were measured for six physical properties. Then, an experiment was performed to assess user satisfaction and emotional factors for pens. The House of Quality (HOQ) was used to obtain the chief physical properties. Results showed that to increase user satisfaction it is necessary to make pens be comfortable, fine, refined, deep, and natural. Also, we found that for high user satisfaction pens need to be heavier and longer, have thick and antislip grips and thin nibs, and their center of gravity should be located close to the nib to increase user satisfaction. This study proposed to investigate the thermal properties and subjective thermal discomfort of five virtual reality headsets, and their relationships. Twenty-seven university students used each of the five headsets for 45 min. Microclimate temperature and relative humidity were measured by miniature dataloggers. Infrared thermography was used to measure temperature distribution on the contact points between user's face and the headsets. Participants reported subjective thermal discomfort associated with using each headset. The average microclimate temperature and relative humidity increased by 7.8 °C and 3.5% respectively after headset use. Overall subjective thermal discomfort increased along with duration of use and came primarily from the display. Applying the linear mixed-effects model showed that subjective thermal discomfort is positively correlated with duration of use, microclimate temperature, relative humidity and display coverage area. Conversely, thermal discomfort is negatively correlated with total coverage area, with microclimate temperature acting as the most significant contributing factor. The headsets were ranked by pairing the objective measurements with subjective evaluations. The aim of this study was to employ validated biological markers to quantify the physiologic consequences of exposure to whole-body vibration (WBV) and evaluate the relative impact of mining vehicle operator vibration exposure on physiological responses as compared to vertical-axial dominant WBV. In a laboratory-based study with a repeated-measures design, we played actual field-measured floor vibration profiles into a 6-degree-of-freedom motion platform to create different realistic WBV exposures 1) vertical-dominant vibration collected from long-haul trucks, 2) multi-axial vibration collected from mining heavy equipment vehicles, and 3) no vibration (control condition). Circulating biomarkers of interest were cortisol and catecholamines (epinephrine and norepinephrine) to assess physiological stress, interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα) to test for inflammation, thiobarbituric acid reactive substances (TBARS) to measure oxidative stress, and myoglobin and plasma creatine kinase to assess muscle damage. link2 We collected blood samples at pre-exposure (0 h), during-exposure (2 and 4 h), and 2 h into recovery after the WBV exposure (6 h) in all four exposure conditions. The results showed that a single, 4-h acute exposure to WBV may not be sufficient to induce skeletal muscle damage, inflammation or physiologic stress measurable in the blood. No significant differences were observed between conditions for any of the biomarkers that could be attributed to the exposure contrast between vertical-dominant and multi-axial WBV exposures. These findings further indicate known complications of WBV exposure likely arise secondary to chronic, repeated exposures that give rise to subclinical stresses that were not captured here. OBJECTIVES Investigate whether a range of cooling methods can extend tolerance time and/or reduce physiological strain in those working in the heat dressed in a Class 2 chemical, biological, radiological, nuclear (CBRN) protective ensemble. METHODS Eight males wore a Class 2 CBRN ensemble and walked for a maximum of 120 min at 35 °C, 50% relative humidity. In a randomised order, participants completed the trial with no cooling and four cooling protocols 1) ice-based cooling vest (IV), 2) a non-ice-based cooling vest (PCM), 3) ice slushy consumed before work, combined with IV (SLIV) and 4) a portable battery-operated water-perfused suit (WPS). Mean with 95% confidence intervals are presented. RESULTS Tolerance time was extended in PCM (46 [36, 56] min, P = 0.018), SLIV (56 [46, 67] min, P less then 0.001) and WPS (62 [53, 70] min, P less then 0.001), compared with control (39 [30, 48] min). Tolerance time was longer in SLIV and WPS compared with both IV (48 [39, 58 min]) and PCM (P ≤ 0.011). After 20 min of work, HR was lower in SLIV (121 [105, 136] beats·min-1), WPS (117 [101, 133] beats·min-1) and IV (130 [116, 143] beats·min-1) compared with control (137 [120, 155] beats·min-1) (all P less then 0.001). PCM (133 [116, 151] beats·min-1) did not differ from control. CONCLUSION All cooling methods, except PCM, utilised in the present study reduced cardiovascular strain, while SLIV and WPS are most likely to extend tolerance time for those working in the heat dressed in a Class 2 CBRN ensemble. Technological developments present diverse opportunities to modernise services for the rail industry. Systems can be implemented to improve passengers' experiences, but these may also affect the experiences of crew working on board trains. This first-of-a-kind research extends the concept of customer journey mapping as a design tool to understand the experiences of train crew. To produce these crew journey maps, interviews and user observation methods were adopted (N = 22). Results show that two main negative touchpoints for the crew occur at the platform-train interface and during revenue protection activities. This paper presents an innovative methodological contribution around journey mapping to better understand rail experiences, but revolving around the crew rather than the expected consumer experience. We conclude this paper proposing requirements for technological systems and indicate opportunities for the design of systems to generate human-centred improvements for the working practices and experiences of train crew. Many factors affect the comfort of automotive seats including pressure distribution, vibration, temperature, and backrest inclination. However, one aspect of seating that has not been well studied is leg splay; splay is a rotation at the hips which causes the knees to move outward. The work presented here identified the ranges of "comfortable" splay in different styles of seats and related changes in seating pressure due to leg splay. Sixteen midsized male participants were tested in six seats a flat control, three mid-sized sedan, a sports car, and a pickup truck. Participants sat with two leg conditions 1) shoulder width apart and 2) rotating their legs to splay to a self-identified, comfortable position. For each test, the participant placed his left leg on a foot support and right leg on a depressible pedal to mimic a driving position. In each posture, leg angle and seat pan pressures were collected. Of the seats tested, the flat wooden seat had the highest possible splay (24.5°). The three sedan seats had similar splay angles (16.1-18.5°). The lowest splay values were in the sports car seat (8.96°) and truck seat (7.46°). This reduction in splay was attributed to the more aggressive bolsters in the sports car and a higher seat design position in the pickup truck seat. Following participant splay the pressures in the seat bolsters increased while the pressure in the left thigh and left buttocks regions decreased. By determining the comfortable ranges of splay and how pressure distribution is affected, seat designers and automobile manufacturers can use these data when evaluating seat designs and occupant positioning. Workers in hospitals, clinics, and contract research organizations who repetitively use syringes have an increased risk for musculoskeletal disorders. This study developed and tested a novel syringe adapter designed to reduce muscle strain associated with repetitive fluid draws. link3 Three syringe plunger extension methods (ring-finger, middle-finger, and syringe adapter) were studied across twenty participants. Electromyogram signals for the flexor digitorum superficialis and extensor digitorum muscles were recorded. The syringe adapter required 31% of the 90th percentile flexor muscle activity as compared to the ring-finger syringe extension method, and 45% the 90th percentile flexor muscle activity as compared to the middle-finger method (p less then 0.001). The greatest differences were observed when the syringe was near full extension. Although the syringe adapter took more time than the other syringe extension methods (1.5 times greater), it greatly helped reduce physical stress associated with repetitive, awkward syringe procedures.
Here's my website: https://www.selleckchem.com/products/rbn-2397.html