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Bifunctional RAFT Agent Focused Planning associated with Polymer/Graphene Oxide Composites.
Soil copper (Cu) supply is used to correct Cu deficiency in many crops grown in southern Mediterranean areas. Oversupply of this fertilizer may contaminate soil and groundwater. This study aims to assess Cu migration in different soils of Moroccan agricultural areas. Three soil samples were collected from different areas. For each soil, three annual leaching rates were tested 35 mm, 237 mm, and 565 mm for a sandy soil; 35 mm, 70 mm, and 140 mm for a clay calcareous soil; and 35 mm, 103 mm, and 247 mm for silty clay soil. The leaching experiments were conducted in columns filled identically up to 30 cm with each soil sample. Then, 0.6 mg of Cu kg-1 was added to the soil surface in the sulfate form (CuSO4.5H2O). The results showed that soil Cu loss increased mainly with leaching rate y = 0.004 x - 0.10 (R2 = 0.97) where y soil Cu loss (10-4 meq 100 g-1) and x leaching rate (mm). The regression analysis did not reveal a significant influence of the soil properties on Cu leaching. However, the Cu loss seems insignificant regarding the no recurrence of high annual leaching rate (over 500 mm), in south Mediterranean areas. Also, soil Cu accumulation risk occurred in all studied soils. For sandy soil, available Cu content was 78% higher in the top layer (0-10 cm) than its content in the middle (10-20 cm) and lower (20-30 cm) layers. Furthermore, a release of bioavailable Cu was recorded in silty clay and clay calcareous soils at a leaching rate of over 70 mm. © 2020 Published by Elsevier Ltd.In addition to needing acute emergency management, blast-mediated traumatic brain injury (TBI) is also a chronic disorder with delayed-onset symptoms that manifest and progress over time. While the immediate consequences of acute blast injuries are readily apparent, chronic sequelae are harder to recognize. BLU-667 Indeed, the identification of individuals with mild-TBI or TBI-induced symptoms is greatly impaired in large part due to the lack of objective and robust biomarkers. The purpose of this study was to address these need by identifying candidates for serum-based biomarkers of blast TBI, and also to identify unique or differentially regulated protein expression in the thalamus in C57BL/6J mice exposed to blast using high throughput qualitative screens of protein expression. To identify thalamic proteins differentially or uniquely associated with blast exposure, we utilized an antibody-based affinity-capture strategy (referred to as "proteomics-based analysis of depletomes"; PAD) to deplete thalamic lysates from blast-treated mice of endogenous thalamic proteins also found in control mice. Analysis of this "depletome" detected 75 unique proteins, many with associations to the myelin sheath. To identify blast-associated proteins eliciting production of circulating autoantibodies, serum antibodies of blast-treated mice were immobilized, and their immunogens subsequently identified by proteomic analysis of proteins specifically captured following incubation with thalamic lysates (a variant of a strategy referred to as "proteomics-based expression library screening"; PELS). This analysis identified 46 blast-associated immunogenic proteins, including 6 shared in common with the PAD analysis (ALDOA, PHKB, HBA-A1, DPYSL2, SYN1, and CKB). These proteins and their autoantibodies are appropriate for further consideration as biomarkers of blast-mediated TBI.Severe stress and depression constitute serious challenges to people in both personal and public health. Numerous university students suffer from depression each year while only fractions of them receive proper and competent treatments. Following the trends of the era, social media has been prevalent among university students and become a new platform to disclose depression references. The purpose of this study is to examine the effects of various stressors and the "Big Five" personality traits towards the intention of disclosing depression. Addition to the disclosure intention, this study also explores if respondents have presented their depression via social media profiles. Over 200 WeChat users were surveyed on their experiences from psychological stress factors under four categories - academy, relationship and practical issues. © 2020 The Authors.This research investigates the domain of indigenous fur clothing for the extreme conditions of the Arctic. link2 The main goal is to reveal the principles of personal wellbeing through observing and analyzing traditional Nenets fur coat and footwear together with the actual experiences of making and using clothing items. For that, we draw from the existing pool of research on functional parameters tested and evaluated in a lab and our empirical data (interviews and participant observations 2013-2016), to eventually come up with two interwoven concepts of clothing based on bio- and cultural mimesis. On the one hand, traditional fur clothing is the result of the biomimetic appropriation of natural abilities of reindeer to withstand severe climates. On the other, it is the embodiment of knowledge on the environment and skills acquired through the dynamic relationship between tools, materials, and personal identities of makers and wearers. This conceptualization, we argue, provides insights into how to both support the very existence in the extreme/severe environment and contribute to personal wellbeing. We conclude by proposing directions for further research towards developing design standards for the emerging multicultural community of Arctic newcomers. © 2020 The Author(s).Indices improve the performance of relational databases, especially on queries that return a small portion of the data (i.e., low-selectivity queries). Star joins are particularly expensive operations that commonly rely on indices for improved performance at scale. The development and support of index-based solutions for Star Joins are still at very early stages. To address this gap, we propose a distributed Bitmap Join Index (dBJI) and a framework-agnostic strategy to solve join predicates in linear time. For empirical analysis, we used common Hadoop technologies (e.g., HBase and Spark) to show that dBJI significantly outperforms full scan approaches by a factor between 59% and 88% in queries with low selectivity from the Star Schema Benchmark (SSB). Thus, distributed indices may significantly enhance low-selectivity query performance even in very large databases. © 2020 The Authors. Published by Elsevier Ltd.Suzuki Indomobil Motor Plant (SIMP) Cakung, East Jakarta, Indonesia generates wastewater containing heavy metals such as nickel, zinc, chromium, copper, and COD derived from the metal coating process using the electroplating system. Electroplating wastewater produced by this company contains Nickel and COD above the quality standards set by the Government of DKI Jakarta (Governor Regulation No. 69/2013). This research aims to analyze and compare the efficiency and kinetics of Nickel complexes and COD removal using the Advanced Oxidation Process (AOP) and Electrocoagulation (EC) method. Electroplating wastewater generated by SIMP Cakung (ratio of plating wastewater to overflow plating wastewater is 130) in this study had characteristics of 379-568 ppm (effluent standard = 75 ppm) of COD, and 87.555-121 ppm (effluent standard = 1 ppm) of Nickel. Preliminary experiments with the factorial design method indicated that independent variables (pH, current density, ozone flow rate, and contact time) had a critical inindustrial wastewater, but also it could reduce the loading of COD for further treatment units by more than 50%. Further studies in the effect of the longer contact time and higher ozone flowrate on COD removal is suggested. © 2020 The Author(s).Culture is a fundamental element of intercultural relationships and contributes to its effectiveness. This methodological study' s purpose is to test the Turkish version of the Intercultural Effectiveness Scale. The scale is a reliable and valid. It is important to include intercultural communication competence in nursing curriculum programs to ensure that students gain all these awareness, skills and behaviors. © 2020 The Author(s).With the introduction of population-based bowel cancer screening, rectal cancer is diagnosed at earlier stages, yet standard treatment still requires the same extensive surgery that is used for more advanced stages. Organ preserving treatment is rapidly developing and is subject of investigation in numerous clinical trials. The STAR-TREC trial is an international, multi-centre randomised trial investigating organ preservation using (chemo)radiotherapy. Patients with small mrT1-3bN0V0M0 tumours are randomized between three arms standard TME, organ preservation with SCRT or with CRT. In this trial, the clinical target volume has been tailored to the early staged disease of the included patients. This mesorectal irradiation volume includes the mesorectum and pre-sacral lymph nodes at the level of the tumour, two centimetres below and cranially up to the S2-3 interspace level. In contrast to conventional irradiation volumes, the lateral lymph nodes and the nodes along the superior rectal artery are excluded. As a result, the dose to the bowel, bladder, anal sphincter and the neurovascular plexus in the lower pelvis is substantially decreased, especially when combined with modern irradiation techniques, such as dynamic arc therapy. These lower doses are expected to lead to decreasing acute and late toxicity and beneficial functional outcomes. The implementation of this novel target volume will be accompanied by an extensive quality assurance program in the STAR-TREC trial. We describe the rationale behind the novel, mesorectal only radiotherapy treatment used in the STAR-TREC trial specifically tailored for early stage disease, with the goal of organ preservation. © 2020 The Author(s).Cerium oxide nanoparticles have been shown to sensitize cancer cells to radiation damage. Their unique redox properties confer excellent therapeutic potential by augmenting radiation dose with reactive oxygen species mediating bystander effects. link3 Owing to its metallic properties, cerium oxide nanoparticles can be visualized inside cells using reflected light and optical sectioning. This can be advantageous in settings requiring none or minimal sample preparation and modification. We investigated the use of reflectance imaging for the detection of unmodified nanoceria in MDA MB231 breast cancer cells along with differential interference contrast imaging and fluorescent nuclear labeling. We also performed studies to evaluate the uptake capability, cellular toxicity and redox properties of nanocaria in these cells. Our results demonstrate that reflectance structured illumination imaging can effectively localize cerium oxide nanoparticles in breast cancer cells, and when combining with differential interference contrast and fluorescent cell label imaging, effective compartmental localization of the nanoparticles can be achieved. The total number of cells taking up the nanoparticles and the amount of nanoparticle uptake increased significantly in proportion to the dose, with no adverse effects on cell survival. Moreover, significant reduction in reactive oxygen species was also observed in proportion to increasing nanoceria concentrations attesting to its ability to modulate oxidative stress. In conclusion, this work serves as a pre-clinical scientific evaluation of the effective use of reflectance structured illumination imaging of cerium oxide nanoparticles in breast cancer cells and the safe use of these nanoparticles in MDA MB231 cells for further therapeutic applications. © 2020 The Authors.
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