Notes

Personal and business factors impacting office cyberbullying associated with nursing staff: A cross-sectional study.
Three of 32 (9.3%) cases of lobular neoplasia were upgraded to malignancy, all LCIS (one pleomorphic and two classical). The most common MRI finding was focal, heterogenous non-mass enhancement with low T2 signal. No clinical features or imaging findings were predictive of upgrade to malignancy.

Incidence of pure lobular neoplasia on MRI guided biopsy is low, with comparatively low incidence of upgrade to malignancy. No imaging or clinical features are predictive of upgrade on surgical excision, therefore, prudent radiologic-pathologic correlation is necessary.
Incidence of pure lobular neoplasia on MRI guided biopsy is low, with comparatively low incidence of upgrade to malignancy. No imaging or clinical features are predictive of upgrade on surgical excision, therefore, prudent radiologic-pathologic correlation is necessary.Shared perceptions of a task among those responsible for its completion are important for achieving successful outcomes. This study proposes a framework for eliciting various aspects of team members' "mental models" (TMMs) of complex medical tasks. The intention is to provide 'proof of concept' for a methodology to measure similarities and differences between team members' perceptions of selected attributes of the task. Applying our framework in a gynecology ward, we use cognitive interviewing and concept mapping to reveal differences between the TMMs of doctor and nurse teams. These group differences are found to reflect limited awareness of the other group's level of involvement, workload, responsibilities and contributions to quality of care. We argue that such differences may lead to frustration, conflict, poor teamwork and risks to patient safety; but once identified, and subject to certain limitations, the differences could be used to develop interventions that will enhance teamwork.
We examined the impact of increasing cognitive load on climbing performance and the impact of climbing on concurrent cognitive task performance.

Generally when two tasks are performed simultaneously performance of one or both suffers relative to performance of each alone. Such dual task decrement is not confined to competing cognitive tasks, but has also been found when one task involves demanding physical activity.

Skilled climbers performed a traverse climb alone and in combination with low and high cognitive load counting tasks, which were also performed alone.

In more realistic physical settings, physical and cognitive tasks will interfere, unlike what some literature using laboratory physical tasks may indicate.

Compared to single task (climb only) performance concurrent counting and climbing resulted in impaired performance. However, climbers appeared to prioritize climbing over cognitive task performance.

The results and this program of research have implications for occupations that involve concurrent demanding physical activity and cognitive task performance. PRéCIS High risk, physical tasks in real world conditions appear to hinder cognitive performance more so than low-risk physical tasks carried out in laboratory conditions.
The results and this program of research have implications for occupations that involve concurrent demanding physical activity and cognitive task performance. PRéCIS High risk, physical tasks in real world conditions appear to hinder cognitive performance more so than low-risk physical tasks carried out in laboratory conditions.Fraud in the food supply system will be exacerbated by shortages caused by climate change and COVID-19's impact. The dried herbs market exemplifies complex supply chains attractive to criminals seeking financial gain. Real-time remote testing is achievable through development of globally accessible chemometric models for portable near infrared devices, deployed throughout supply chains. This study describes building of models for detection of oregano adulteration, on portable near infrared devices, and comparison to a laboratory-based Fourier-Transform Infrared spectroscopy method. 33/34 portable devices were able to correctly classify 5 out of 6 samples successfully with all adulterated samples being correctly classified following the use of appropriate transferability pre-processing routines. The devices native setup shows limited ability to perform a true screening of oregano using the setup offered. However modifications to the setup could in the future offer a solution that facilitates fit-for-purpose real time detection of adulterated samples within the supply chain.Surveillance of illegal use of growth promoters such as β2-agonists in food producing animals rely on the detection of drug residues by LC-MS/MS. Screening strategies focusing on indirect physiological responses following administration of active compounds are promising approaches to strengthen existing targeted methods and ensure food safety. A metabolomics analysis based on LC-HRMS was carried out on liver extracts from bulls experimentally treated with clenbuterol combined with dexamethasone (n = 8) to mimic a potential anabolic practice, and control animals (n = 8). Nicotinic acid and 5'-deoxy-5'-methylthioadenosine were identified as biomarkers of treatment. Ratio values of such markers to others of the same metabolic pathways (nicotinamide or methionine) were used to develop a classification model to assign animals as treated with clenbuterol or non-treated. The classification model was tested on an external validation set comprising 74 animals either treated with different anabolic compounds (β2-agonists, sexual steroids, corticosteroid), or non-treated, showing 100% sensitivity and specificity.
This study aimed to assess the feasibility of Self-gated Non-Contrast-Enhanced Functional Lung (SENCEFUL) MRI for detection of pulmonary perfusion deficits in patients with cystic fibrosis.

Twenty patients with cystic fibrosis and 20 matched healthy controls underwent SENCEFUL-MRI at 1.5 T with reconstruction of perfusion and perfusion phase maps (i.e. comparable to pulse wave delays). Four blinded readers rated both types of maps separately followed by simultaneous assessment thereof. Perfusion phase data was plotted in histograms and a Peak-to-Offset ratio was calculated for comparison to subjective scoring and correlation (Spearman) to lung function parameters. Sensitivity, specificity and positive and negative predictive values were calculated for subjective scoring and Peak-to-Offset ratios. Intraclass correlation (ICC) was used to assess the interrater agreement.

Readers attributed pathological ratings 2.2-3.5 times more frequently to the CF-group. The sensitivity with regard to a correct assignment an objective future marker for perfusion impairment.Biochar, over the last two decades, has become the focal point of agro-environmental research given its unique functionality, cost-effectiveness and recyclability potentials. It has been studied intensively as an efficient scavenger for the decontamination of several organic and inorganic pollutants. However, the ability of biochar to modulate nitrogen (N) dynamics in soil and terrestrial ecosystems remains controversial. This work deliberates on the premise that biochar functionality enables maximizing N use efficiency by reducing the potential losses induced by volatilization/emission and runoff/leaching as well as stimulating available N inputs derived from symbiotic and nonsymbiotic biological nitrogen fixation (BNF) and N mineralization/retention. For this purpose, we carried out a critical review on different intriguing dimensions surrounding the potentiality of biochar to modulate the complicated reactions of soil N cycle with emphasis on its pros and cons. Previous studies in the literature have shown contradictory results with a noticeable significant effect of biochar toward stimulating available N inputs and reducing its losses under short-term laboratory experimentations. However, long-term field investigations have indicated minimal or negative effects in this regard. Furthermore, some of the experimentations lack appropriate controls or fail to account for inputs or losses associated with biochar particles. It is thus of great importance to contextualise lab-scale experimentations based on real field data to provide a holistic approach for understanding the complicated reactions responsible for modulating N cycle in the charosphere. Additionally, biochar functionalization should be highlighted in the foreseeable research to develop fit-for-purpose forms tailored in agro-environmental applications.Exposure to environmental neurotoxicants is a significant concern due to their potential to cause permanent or irreversible damage to the human nervous system. Glucagon Receptor antagonist Here, we present the first dedicated knowledgebase, NeurotoxKb 1.0, on environmental neurotoxicants specific to mammals. Using a detailed workflow, we have compiled 475 potential non-biogenic neurotoxicants from 835 published studies with evidence of neurotoxicity specific to mammals. A unique feature of NeurotoxKb 1.0 is the manual curation effort to compile and standardize the observed neurotoxic effects for the potential neurotoxicants from 835 published studies. For the 475 potential neurotoxicants, we have compiled diverse information such as chemical structures, environmental sources, chemical classification, physicochemical properties, molecular descriptors, predicted ADMET properties, and target human genes. To better understand the prospect of human exposure, we have explored the presence of potential neurotoxicants in external exposomes via two different analyses. By analyzing 55 chemical lists representing global regulations and guidelines, we reveal potential neurotoxicants both in regular use and produced in high volume. By analyzing human biospecimens, we reveal potential neurotoxicants detected in them. Lastly, a construction of the chemical similarity network and ensuing analysis revealed the diversity of the toxicological space of 475 potential neurotoxicants. NeurotoxKb 1.0 is accessible online at https//cb.imsc.res.in/neurotoxkb/.Magnetic field-influenced nanofiltration membrane by blending of magnetic multi-functionality green modifier (CS-EDTA-mGO) was fabricated via phase inversion processes. Migration of superparamagnetic nanofiller particles into top surface layer of M6 NF-membrane by incorporating external magnetic-filed during casting phase improved the hydrophilicity, as well as formation of large pores diameters (1.57 nm) which offer a flux enhancement (84.2 kg/m2h), excellent fouling resistance (Rr of 26.4%, Rt of 39.4% and Rir of 25.0%) and highest flux recovery ratio (75.9%). The order of salt rejection for all modified NF-membranes was Na2SO4 > MgSO4 > NaCl and the efficiency of the membranes to reject salts follows the order of M6 > M4 > M0. The performance of M6 as magnetic field-influenced membrane in rejection of RR195 and MB was 21% and 42% higher than unblended membrane (M0), respectively. The highest removal efficiency of Pb2+ and Cd2+ observed for M6 (98.2% and 93.6%, respectively). M6 was more efficient in concurrent removing pollutants from mixed-solute feed. In this case, the existing of Na2SO4 enhanced the retention of RR195 from 97.2% to 99.3%. Long-term operation tests demonstrated the excellent stability of M6 for 18 h filtration with a limited reduction in rejection and water flux of single salt solution. M6 membrane has found potential application in cyclic textile wastewater treatment which the water flux was found to be constant over 3-repeated filtration cycles.
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