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Crested auklets (Aethia cristatella) are colonial seabirds with brilliant orange bills during the breeding season. We characterized the bill pigment with spectroscopy methods (resonance Raman, fluorescence, absorbance). We excluded carotenoids as a possible chromophore and showed that the pigment most closely resembles pterins. Like pterins the bill pigment fluoresces, and it occurred in two phenotypes that may differ geographically, perhaps due to environmental heterogeneity. The pigment is unique in the Genus Aethia, and its spectra did not match any known molecule. The UV-Vis absorbance spectrum of the bill pigment overlaps with the extracted pigment of euphausiids, a favored food of crested auklets. A color preference associated with prey may have favored characteristics of the crested auklet's accessory bill plates. Crest size, a signal of dominance, tended to correlate positively with highest fluorescence in the single-band phenotype. Brighter bills may function in self-advertisement and verify the status signal of the crest ornament. We tested for a behavioral preference using identical decoys that differed only in bill fluorescence. Crested auklets approached models with fluorescent bills at a higher frequency. In cases where sex of crested auklets was known, males responded at a higher frequency to fluorescent bills, but females did not. In an evolutionary context, bill fluorescence could have conferred an advantage in social interactions, e.g., in dimly lit rock crevices. Bill brightness and color may communicate success in foraging and may function as an honest signal of mate quality.The recent COVID-19 emergency has shaped economic performance across all sectors, and the fisheries and aquaculture sector did not come out unscathed. The need to protect against risks has always been primary for economic operators, but COVID-19 has accentuated the need to obtain coverage for health risks. Bcl-2 protein In this regard, the European Union has moved quickly with an amendment art. 35 of European Maritime and Fisheries Fund (Regulation [EU] No. 508/2014), including "public health crises" among the causes considered valid for compensation in mutual funds. In this paper, we analyze the evolution of Regulation 508, focusing on Article 35 and its most recent amendments, to understand if the new reform is adherent to the needs of the fisheries sector in Italy, one of the only two States that have documented in their Operational Plans the intention to implement mutual funds. The work involved an empirical analysis through the use of multivariate statistics carried out on 61 Italian stakeholders. Several company profiles were identified and then the likelihood of subscribing to a mutual fund was estimated based on their focus on health crises. The work underlines that the amendments meet the demands of the sector for improved mutual fund clauses, but it's not yet an attractive tool for the Italian market.The COVID-19 pandemic has created significant challenges for energy transition. Concerns about the overwhelming emphasis on economic recovery at the cost of energy transition progress have been raised worldwide. More voices are calling for "green" recovery scheme, which recovers the economy while not compromising on the environment. However, limited academic attention has been paid to comprehensively investigating the implications of COVID-19 for global energy transition. This study thus provides a comprehensive analysis of the dynamics between energy transition and COVID-19 around the world and proposes a low-carbon energy transition roadmap in the post-pandemic era. Using energy data from the International Energy Agency (IEA), we first summarized and reviewed the progress of energy transition prior to COVID-19. Building on prior progress, we identified the challenges for energy transition during the pandemic from the perspectives of government support, fossil fuel divestment, renewable energy production capacity, global supply chain, and energy poverty. However, the pandemic also generates opportunities for global energy transition. We hence also identified potential opportunities for energy transition presented by the pandemic from the perspectives of price competitiveness, policy implementation efficiency, and renewable energy strengths. We further provided an in-depth discussion on the impact of current worldwide economic recovery stimulus on energy transition. Based on the identified challenges and opportunities, we proposed the post-pandemic energy transition roadmap in terms of broadening green financing instruments, strengthening international cooperation, and enhancing green recovery plans. Our study sheds light on a global low-carbon energy transition framework and has practical implications for green recovery schemes in post-pandemic times.In this study, we provide evidence suggesting that in countries with severe disaster experience (SDE), the response to the coronavirus disease 2019 (COVID-19) pandemic is characterized by a higher level of attention in the population, more timely market responses, and stricter government containment measures. Specifically, we find that during the first COVID-19 outbreak in Wuhan, China, people in countries with SDE searched for related information more frequently on Google than did people in countries with mild disaster experience (MDE). Moreover, we find that a higher level of attention to COVID-19, as measured by Google search index usage, led to greater declines in stock market indexes in countries with SDE than in those with MDE. Finally, we find that compared with countries with MDE, those with SDE implemented more stringent social distancing policies in response to domestic COVID-19 outbreaks, and individuals in the latter group of countries were more likely to follow government-imposed rules of social distancing in both the early outbreak and reopening phases. Our findings suggest that disaster experience increases risk aversion and is an essential mechanism by which individuals, markets, and countries respond to COVID-19 in a timely manner.There may be a "silent epidemic" of SARS-CoV-2 in deer in the US, and other wildlife might carry it too, finds Michael Le Page.In this work, a new version of Rényi's divergence is presented. The expression obtained is used as a tool to identify molecules that could share some chemical or structural properties, and a data basis set of 1641 molecules is used in this study. Our results suggest that this new form of Rényi divergence could be a useful tool that will eventually permit complementary studies in which the main goal is to obtain molecules with similar properties.Unpredictable natural and man-made disasters highlight importance of humanitarian supply chain (HSC) to serve people and affected areas. The main challenges of applying effective relief operations are creating "swift trust" and "coordination" between aid organizations. Implementation of Industry 4.0 facilitates coordination and swift trust within HSC performance. The study intends to assess the readiness status of swift trust and coordination between stakeholders as well as to recommend the most suitable Industry 4.0 tools for improving relief operations. Firstly, a comprehensive set of critical success factors for implementing Industry 4.0 tools are introduced. The factors are categorized into limited groups using Exploratory Factor Analysis. In the next step, hierarchy fuzzy expert system is designed for assessing the readiness status of swift trust and coordination as well as to suggest the most suitable Industry 4.0 tool for enhancing HSC performance within given case study. The framework was applied for three aid organizations to address the pandemic disease in Iran. The outcome denotes that the organization has the highest readiness in logistic and transparency while information quality received the lowest readiness value. In addition to that, the organization should invest on the development of Industry 4.0 enablers including "Internet of Things and Big Data Analytics". The study extends organizational information process theory within HSC for reaching competitive advantage by information processing. The study suggests theoretical and practical implications by introducing a comprehensive set of critical success factors for implementation of Industry 4.0 and providing practical advice for enhancing HSC performance.We test for the contagion effects stemming from the Greek debt crisis in the daily 10-year sovereign bond yield spreads in nine Economic and Monetary Union (EMU) countries. To this end, we estimate the dynamic conditional correlation (DCC) model of Engle (2002) from January 01, 2003 to December 31, 2015. In addition, we calculate and plot the upper and lower bounds of the confidence interval for each DCC series. To the best of our knowledge, this approach of Kchaou and Bellalah (2020) has never been used to study the contagion of the subprime and Greek crises between the 10-year sovereign bond yield spreads of the main EMU countries. Consequently, this approach enables us to compare our results with those of previous works based on other methods. It also offers useful insights to policy makers to address the contagion effect through the implementation of adequate measures. Although the Greek spread played the role of a global factor for the majority of countries during the observation period, the results invalidate the existence of contagious episodes resulting from the Hellenic crisis. We justify these findings either by the weakness of the weight of the Greek economy in the euro area or by the effectiveness of the unconventional monetary policies taken by the European Central Bank (ECB), the bailouts for Greece in 2010, 2012 and 2015 and the austerity measures and structural reforms implemented by the governments of EMU countries. Moreover, DCC between Greece and the other countries have shown a downward behavior during the acute phases of Greek crisis, suggesting a disintegration of the Hellenic bond market with those of other euro area countries during periods of financial turmoil. Furthermore, the results indicate that the subprime crisis affected a large part of these markets well before the bankruptcy of Lehman Brothers. All these findings provide valuable information for international investors, central bankers and policymakers.Pelizaeus-Merzbacher-Like Disease 1 is a genetic disorder affecting the central nervous system with an autosomal recessive inheritance pattern. It is a rare genetic disorder that affects the central nervous system. In this report, we demonstrated the clinical and paraclinical features of an Iranian consanguine pedigree with suspected hypomyelinating leukodystrophy, without any defined diagnosis. The proband, a 15-month-old girl, visited the Razi pathobiology and medical genetic laboratory of Karaj, where the study was conducted in 2020. Following whole-exome sequencing analysis of the proband and segregation analysis, a novel pathogenic mutation was discovered. GJC2 (NM_020435.4)c.1096dupG was found to be homozygous in the proband and heterozygous in both parents. This mutation was in the coding region of the protein, which results in D366Gfs*126 (p.Asp366GlyfsTer126). The site of mutation was at the 3' region of the connexin superfamily domain. The frameshift results in a different peptide sequence of the C-terminal and extended protein.
Website: https://www.selleckchem.com/Bcl-2.html
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