Notes

Synthesis in the C4-C16 Polyketide Fragment regarding Portimines A and also W.
There is an increasing consensus that exercise is a medicine and that regular exercise can effectively improve and prevent metabolic diseases such as diabetes. Islet cells are the endocrine of the pancreas and vital to the development of diabetes. Decades of developmental research in exercise intervention and the health of islet cells confirmed that exercise exerts beneficial effects on the function, proliferation, and survival rate of islet cells. However, the precise exercise reference scheme is still elusive. To accomplish this goal, we searched and analyzed relevant articles, and concluded the precise exercise prescription treatments for various species such as humans, rats, and mice. Each exercise protocol is shown in the tables below. These exercise protocols form a rich pipeline of therapeutic development for exercise on the health of islet cells.Using m-Health apps can provide researchers and others with an effective way for improving physical activity (PA) and healthy lifestyle behaviors. The promotion of health should move from a model focused on the physical and biological basis of illness and towards a focus on the behavioral changes that support health. Therefore, the aims of the current study were to improve PA (step-counts) and body weight using a theory-based m-Health app. A 12-week randomized treatment trial was carried out at Texas A&M University, Texas, college station. College students (n = 130) were recruited. They were randomized in an equal ratio of 11 to intervention (m-Health app) (n = 65) and control (n = 65) conditions. The response rate was (87.6%). Both groups utilized a Smartphone app. The intervention group received PA goals of (10,000 steps/day), using an m-Health app. The control group was provided with information related to daily recommended PA levels. The primary change was daily step count between the baseline and follow-up. The secondary outcome was the body mass index (BMI). Descriptive statistics were used to summarize the baseline differences between the control and intervention groups. Independent sample t-test were used for comparison between the intervention and control groups. Post-intervention PAs were higher for the intervention group (mean = 54,896.) vs. control group (mean = 45,530.12; p < 0.05). The intervention group's step-counts increased significantly (pre-mean = 40,320.38 steps per week; post-mean = 54,896.27 steps per week, p < 0.05). The body-weight changes were significant among the intervention group (p < 0.05). m-Health apps can increase PA and improve body weight, with goal setting and feedback as key intervention components. Future studies should personalize PA goals and feedback.In order to improve the phosphate adsorption capacity of Ca-loaded biochar at a wide range of pH values, Ca (oyster shell) was loaded as Ca(OH)2 on the tobacco stalk biochar (Ca-BC), which was prepared by high-temperature calcination, ultrasonic treatment, and stirring impregnation method. The phosphorus removal performance of Ca-BC adsorption was studied by batch adsorption experiments, and the mechanism of Ca-BC adsorption and phosphorus removal was investigated by SEM-EDS, FTIR, and XRD. The results showed that after high-temperature calcination, oyster shells became CaO, then converted into Ca(OH)2 in the process of stirring impregnation and had activated the pore expansion effect of biochar. According to the Langmuir model, the adsorption capacity of Ca-BC for phosphate was 88.64 mg P/g, and the adsorption process followed pseudo-second-order kinetics. The Ca(OH)2 on the surface of biochar under the initial pH acidic condition preferentially neutralizes with H+ acid-base in solution, so that Ca-BC chemically precipitates with phosphate under alkaline conditions, which increases the adsorption capacity by 3-15 times compared with other Ca-loaded biochar. Ca-BC phosphate removal rate of livestock wastewater (pig and cattle farms) is 91~95%, whereas pond and domestic wastewater can be quantitatively removed. This study provides an experimental basis for efficient phosphorus removal by Ca-modified biochar and suggesting possible applications in real wastewater.The Union of Soviet Socialist Republics (USSR) collapsed in 1991 and separated into the 15 post-Soviet countries Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine, and Uzbekistan. The post-Soviet countries have faced many economic problems, including unemployment. The association between suicide and unemployment in post-Soviet countries has not been well studied. Here, we researched the annual suicide rate and the unemployment rate during the 28-year period from 1992 to 2019 in the 15 post-Soviet countries. We calculated the correlation coefficients between the suicide rate and the unemployment rate in each of the countries during this period, and we determined the association between the suicide rate and unemployment rate. Our major findings were that (1) the suicide rates among both males and females were significantly associated with the unemployment rate in nearly half of the 15 countries, and (2) for nearly 70% of the males in the entire set of 15 countries, there was an association between the suicide rate and the unemployment rate. 3',3'-cGAMP STING activator Suicide-prevention researchers and organizations should be aware of our findings, and specific suicide-prevention measures based on these results are desirable.This article is a continuation of the research on personality in combat sports in karate. The authors' goal was to verify the relationship between personality and age of kyokushin karate practitioners. The male national team of Ukraine in karate kyokushin (N = 7) participated in the personality study with the use of the Big Five model. The NEO-FFI (NEO Five-Factor Inventory) Personality Questionnaire was applied as a research tool and the package of statistical methods IBM SPSS Statistics 27.0 (IBM Polska, Warszawa, Poland) was used to compute the research results. The study showed that there were differences in the intensity of openness to experiences between individual samples only at the level of the statistical trend. Masters showed a higher level of openness to experiences in relation to juniors (p = 0.081) and seniors (p = 0.097). Also, a negative and strong correlation between the intensity of neuroticism and conscientiousness among the respondents was noted. A conclusion was drawn that, with age, karatekas probably manifest greater openness to experience, which is the result of their sports experience, high sports level and pro-health values of karate. On the other hand, good emotional adaptation of karatekas is strictly related to conscientiousness.Rural tourism in developing countries has been regarded as a means for rural development, environment conservation and poverty alleviation. This study aims to examine the determining factors for rural households' willingness to participate in rural tourism in western areas under the context of China's rural revitalization strategy. Based on survey data from 22 tourism poverty alleviation villages located in the poor areas of western China, we characterize our results by stating that rural households' livelihood resilience "push" on their willingness to participate, and that poverty alleviation policy perception and involvement "pull" on it. Among distinct livelihood adaptive strategy groups, i.e., farming-oriented households, migratory-oriented households and tourism-participating households, this study also revealed that buffer capacity was a significant driving force for the three types of household's willingness. Positive poverty alleviation policy perception could attract migratory households to return to their hometowns to start tourism businesses; however, better self-organizing capacity decreased their willingness. In addition, both self-organization and learning capacity and positive policy perception and involvement encouraged tourism-participating households to engage in tourism activities continually. Finally, some practical implications and recommendations for further research are also discussed.Analyzing the supply and demand of ecosystem services and the regional balance pattern is an important basis for improving the ecological management level. Taking the Yangtze River economic belt as the study area, the spatiotemporal characteristics and balance pattern of ecosystem service supply and demand are quantitatively revealed based on equivalent factors, supply and demand balance modeling and quantile regression. The results show that (1) the ecosystem services value in the research area experienced a change process of "increase-decrease-increase" from 2000 to 2020. The ecological service value of cultivated land and grassland presented a continuous decline, with decreases of 20.446 billion and 4.53 billion yuan, respectively, in the past 20 years, with reduction rates of -4.82% and -3.98%, respectively. (2) The demand for ecosystem services showed an unbalanced and phased growth trend. The total demand for ecosystem services showed heterogeneity and agglomeration effects in space. High demand and higher demand areas are mainly distributed in the regions with relatively developed population and economy, including Yangtze River Delta urban agglomeration, "Changsha-Zhuzhou-Xiangtan" urban agglomeration, Poyang Lake Plain, Jianghan Plain and Chengdu Plain. (3) The overall pattern of the supply-demand balance of ecosystem services has changed little; however, there have also been significant changes in certain areas in individual years.The safety behavior of vocational school students is worth noting. The current study is aimed to examine the effect of self-control demands on safety behavior. Drawing on the Self-Control Resource Model, we predict that self-control demands have a negative effect on safety behavior through ego depletion and perceived teacher support moderates the link among self-control demands, ego depletion, and safety behavior. A two-wave survey was conducted and 285 vocational students participated in our study. Mediation and moderated mediation modeling analyses were carried out. Results showed that ego depletion fully mediated the link between self-control demands and safety behavior. Moreover, perceived teacher support moderated the relationship between self-control demands, ego depletion and safety behavior; for students who perceived high levels of teacher support, the negative effect of self-control demands on safety behavior via ego depletion was insignificant, while for students who perceived low levels of teacher support, their negative effect was significant. The present study clarifies the effects of self-control demands on safety behavior through the resource depletion process and highlights the importance of teacher support in buffering the negative effect of self-control demands on workplace safety. Enhancing safety management, engaging in a resource recovery activity, and providing teacher support training are effective ways to maintain high levels of workplace safety.Global climate change presents a profound threat to the survival and continued development of humanity. The present study featured a survey of 3005 adolescents in China on 13 December 2021, aiming to determine whether climate change beliefs (including recognition of the existence of climate change, cognition of the causes of climate change, and climate change risk perception) influence their engagement in energy-conservation behaviors. Concurrently, the psychological mechanism underlying the influence of environmental concerns on the above relationship was also tested. The results showed that, among youths, climate change belief positively predicts engagement in energy-conservation behaviors. Specifically, awareness of the existence of climate change, knowledge of the causes of climate change, and climate change risk perception all positively predict engagement in energy-conservation behaviors. Further, environmental concerns were found to play a mediating role in the relationship between climate change beliefs and energy-conservation actions.
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