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Is Bigger Better? Residing Donor Elimination Size because Measured from the Donor CT Angiogram throughout Projecting Contributor and Receiver eGFR after Living Donor Kidney Hair transplant.
This paves the way for enhancing the role of wearable devices in emotional state recognition in everyday life.Existing literature suggests that the probability density function (pdf) of surface Electromyography (sEMG) signals follows either a Gaussian or Laplacian model. In this paper, a Laplacian-Gaussian mixture model is proposed for the EMG signals extracted from the upper limbs. The model is validated using both quantitative and qualitative perspectives. Specifically, for a benchmark dataset, the Kullback-Leibler (KL) divergence is computed between the proposed model and the histogram based empirical probability density function (mpdf). For a sample signal, a goodness of fit plot with R squared value and a visual comparison between the histogram based mpdf and the estimated pdf from the proposed model are presented. Moreover, the Expectation-Maximization (EM) algorithm is derived for the estimation of the parameters of the proposed mixture model. The weight of the Laplacian component is computed for each of the signals from a benchmark dataset. It has been empirically determined that the Laplacian component has a major contribution to the mixture.Post-prandial hypoglycemia occurs 2-5 hours after food intake, in not only insulin-treated patients with diabetes but also other metabolic disorders. For example, postprandial hypoglycemia is an increasingly recognized late metabolic complication of bariatric surgery (also known as PBH), particularly gastric bypass. Underlying mechanisms remain incompletely understood to date. Besides excessive insulin exposure, impaired counter-regulation may be a further pathophysiological feature. To test this hypothesis, we need standardized postprandial hypoglycemic clamp procedures in affected and unaffected individuals allowing to reach identical predefined postprandial hypoglycemic trajectories. Generally, in these experiments, clinical investigators manually adjust glucose infusion rate (GIR) to clamp blood glucose (BG) to a target hypoglycemic value. Nevertheless, reaching the desired target by manual adjustment may be challenging and possible glycemic undershoots when approaching hypoglycemia can be a safety concern for patients. In this study, we developed a PID algorithm to assist clinical investigators in adjusting GIR to reach the predefined trajectory and hypoglycemic target. The algorithm is developed in a manual mode to permit the clinical investigator to interfere. We test the controller in silico by simulating glucose-insulin dynamics in PBH and healthy nonsurgical individuals. Different scenarios are designed to test the robustness of the algorithm to different sources of variability and to errors, e.g. outliers in the BG measurements, sampling delays or missed measurements. The results prove that the PID algorithm is capable of accurately and safely reaching the target BG level, on both healthy and PBH subjects, with a median deviation from reference of 2.8% and 2.4% respectively.Clinical relevance- This control algorithm enables standardized, accurate and safe postprandial hypoglycemic clamps, as evidenced in silico in PBH patients and controls.High-density surface electromyography (EMG) has been proposed to overcome the lower selectivity with respect to needle EMG and to provide information on a wide area over the considered muscle. Motor units decomposed from surface EMG signal of different depths differ in the distribution of action potentials detected in the skin surface. We propose a noninvasive model for estimating the depth of motor unit. We find that the depth of motor unit is linearly related to the Gaussian RMS width fitted by data points extracted from motor unit action potential. Simulated and experimental signals are used to evaluate the model performance. The correlation coefficient between reference depth and estimated depth is 0.92 ± 0.01 for simulated motor unit action potentials. Due to the symmetric nature of our model, no significant decrease is detected during the electrode selection procedure. We further checked the estimation results from decomposed motor units, the correlation coefficient between reference depth and estimated depth is 0.82 ± 0.07. For experimental signals, high discrimination of estimated depth vector is detected across gestures among trials. These results show the potential for a straightforward assessment of depth of motor units inside muscles. We discuss the potential of a non-invasive way for the location of decomposed motor units.Cardiovascular (CV) diseases are the leading cause of death in the world, and auscultation is typically an essential part of a cardiovascular examination. The ability to diagnose a patient based on their heart sounds is a rather difficult skill to master. Thus, many approaches for automated heart auscultation have been explored. However, most of the previously proposed methods involve a segmentation step, the performance of which drops significantly for high pulse rates or noisy signals. In this work, we propose a novel segmentation-free heart sound classification method. Specifically, we apply discrete wavelet transform to denoise the signal, followed by feature extraction and feature reduction. Then, Support Vector Machines and Deep Neural Networks are utilised for classification. On the PASCAL heart sound dataset our approach showed superior performance compared to others, achieving 81% and 96% precision on normal and murmur classes, respectively. In addition, for the first time, the data were further explored under a user-independent setting, where the proposed method achieved 92% and 86% precision on normal and murmur, demonstrating the potential of enabling automatic murmur detection for practical use.Accurate torque estimation during dynamic conditions is challenging, yet an important problem for many applications such as robotics, prosthesis control, and clinical diagnostics. Our objective is to accurately estimate the torque generated at the elbow during flexion and extension, under quasi-dynamic and dynamic conditions. High-density surface electromyogram (HD-EMG) signals, acquired from the long head and short head of biceps brachii, brachioradialis, and triceps brachii of five participants are used to estimate the torque generated at the elbow, using a convolutional neural network (CNN). We hypothesise that incorporating the mechanical information recorded by the biodex machine, i.e., position and velocity, can improve the model performance. To investigate the effects of the added data modalities on the model accuracy, models are constructed that combine EMG and position, as well as EMG with both position and velocity. R2 values are improved by 2.35%, 37.50%, and 16.67%, when position and EMG are used as inputs to the CNN models, for isotonic, isokinetic, and dynamic cases, respectively compared to using only EMG. The model performances improves further by 2.29%, 12.12%, and 20.50% for isotonic, isokinetic, and dynamic conditions, when velocity is added with the EMG and position data.Analysis and classification of electromyography (EMG) signals are crucial for rehabilitation and motor control. This study investigates electromyogram (EMG) time-frequency representations and then creates conventional and deep learning models for EMG signal classification. Firstly, a dataset of single-channel surface EMG signals has been recorded for four subjects to differentiate between forearm flexion and extension. Then, different time-frequency EMG representations have been used to build conventional and deep learning models for EMG classification. We compared the performance of pre-trained convolutional neural network models, namely GoogLeNet, SqueezeNet and AlexNet, and achieved accuracies of 92.71%, 90.63% and 87.5%, respectively. Also, data augmentation techniques on the levels of raw EMG signals and their time- frequency representations helped improve the accuracy of GoogLeNet to 96.88%. Furthermore, our approach demonstrated superior performance on another publicly available 10-class EMG dataset, and also using traditional classifiers trained on hand-crafted features.In this paper, we propose to learn a spatial filter directly from Electroencephalography (EEG) signals using graph signal processing tools. We combine a graph learning algorithm with a high-pass graph filter to remove spatially large signals from the raw data. This approach increases topographical localization, and attenuates volume-conducted features. We empirically show that our method gives similar results that the surface Laplacian in the noiseless case while being more robust to noise or defective electrodes.Clinical relevance- The proposed method is an alternative to the surface Laplacian filter that is commonly used for processing EEG signals. It could be used in cases where this standard approach does not provide satisfying results (low signal-to-noise ratios due to a low number of epochs, defective electrodes). This could be particularly interesting in case of an electrode defect, as it can happen in clinical practice.Depression is a common and serious mental illness which negatively affects daily functioning. To prevent the progression of the illness into severe or long-term consequences, early diagnosis is crucial. We developed an automated speech feature analysis application for depression and other psychiatric disorders derived from a developed Thai psychiatric and verbal screening test. The screening test includes Thai's version of Patient Health Questionnaire-9 (PHQ-9) and Hamilton Depression Rating Scale (HAM-D), and 32 additional emotion-induced questions. Case-control study was conducted on speech features from 66 participants. Twenty seven of those had depression (DP), 12 had other psychiatric disorders (OP), and 27 were normal controls (NC). The five-fold cross-validation from 6 settings of 5 classifiers with the combination of PHQ-9 and HAM-D scores, and speech features were examined. Results showed highest performance from the multilayer perceptron (MLP) classifier which yielded 83.33% sensitivity, 91.67% specificity, and 83.33% accuracy, where negative-emotional questions were most effective in classification. The automated speech feature analysis showed promising results for screening patients with depression or other psychiatric disorders. PIK-75 purchase The current application is accessible through smartphone, making it a feasible and intuitive setup for low-resource countries such as Thailand.Heart rate variability (HRV) is a non-stationary, irregularly sampled signal that represents changes in heart rate over time. The HRV spectrum can be divided into four main ranges covering high, low, very low and ultra-low frequencies. The components lying in these bands, both amplitude and frequency modulated, provide valuable information about various physiological processes. The aim of this study was to verify the usefulness of adaptive variational mode decomposition (AVMD) in the extraction of these components from overnight HRV. The effectiveness of this new approach was compared to multiband filtering (MBF) using a synthetically generated signal, as well as real data from three patients. AVMD turned out to be more robust and effective than MBF, particularly in the high and low frequency ranges, making it a reliable method for deriving the HRV frequency components.Clinical Relevance-The extracted frequency components of heart rate variability provide insight into the regulation of basic physiological processes by the autonomic nervous system.
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