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Non-operative management is often the treatment of choice in cases of complicated appendicitis and routine interval appendectomy is not usually recommended. Actually, recent studies show an alarming number of appendiceal neoplasms following interval appendectomy. The aim of this study is to evaluate the prevalence of appendiceal neoplasms and their histological types after interval appendectomy for complicated appendicitis in adults.

A comprehensive literature search of the PubMed, Scopus and Web of Science databases was conducted according to the PRISMA statement. Studies reporting appendiceal neoplasm rates after interval appendectomy and histopathological characteristics were included. The most recent World Health Organization (WHO) classification of malignant tumours was considered. A pooled prevalence analysis for both prevalence and pathology was performed.

A total of eight studies was included seven retrospective series and one randomized controlled trial. The pooled prevalence of neoplasms after interval appendectomy was 11% (95% CI 7-15; I
=37.5%, p=0.13). Appendiceal mucinous neoplasms occurred in 43% (95% CI 19-68), adenocarcinoma in 29% (95% CI 6-51), appendiceal neuroendocrine neoplasm in 21% (95% CI 6-36), globet cell carcinoma in 13% (95% CI -2-28), adenoma or serrated lesions in 20% (95% CI -0-41) of cases.

The risk of appendiceal neoplasm in patients treated with interval appendectomy for complicated appendicitis is 11%; mucinous neoplasm is the most common histopathological type. Further studies should investigate this association in order to clarify the biological pathway and clinical implications.
The risk of appendiceal neoplasm in patients treated with interval appendectomy for complicated appendicitis is 11%; mucinous neoplasm is the most common histopathological type. Further studies should investigate this association in order to clarify the biological pathway and clinical implications.
Identification of a poorly positioned hip radiograph often requires a subjective assessment by the radiographer, which, due to the observer dependency of this method, may have conflicting opinions between radiographers. A quantitative approach may be a better personnel independent approach for assessing an optimally positioned hip radiograph. A Shenton line length femur neck length ratio (SLFLR) could be used to achieve this, which is the aim of this study.

Seventy-three (48 digital and 25 analog) optimally positioned non-pathological hip radiographs of asymptomatic patients aged between 20 and 59 years and reported by the consultant radiologist as normal were conveniently selected. Three different radiographers, each blinded to the results of the other two, measured the Shenton line length and the femur neck length with the aid of flexible and straight meter rules for the analog images and inbuilt electronic calipers for the digital images. Bland-Altman method of agreement was used to assess for reproducibility and reliability of the measurements while the 5th, 25th, 75th, and 95th percentiles of the SLFLR were computed.

The mean±SD SLFLR for both genders were 1.07±0.08cm (females 1.06±0.09 and males 1.08±1.07cm). The measurements demonstrated high reproducibility and reliability between (interclass correlation coefficient 0.993) and within (intraclass correlation coefficient 0.998) radiographers. The 5th, 25th, 75th, and 95th percentile values of the SLFLR are 0.90, 1.03, 1.12, and 1.18.

For a hip radiograph to be reported as optimal for patients aged 20-59 years, the SLFLR should be between 0.90 and 1.18. This method is highly reproducible and repeatable and could be adopted for quantitative assessment of radiographs.

The SLFLR could be used as an additional tool by the radiographer to quantitatively assess for a well-positioned hip radiograph.
The SLFLR could be used as an additional tool by the radiographer to quantitatively assess for a well-positioned hip radiograph.
Radiographers' engagement in research is important for the development of evidence-based practice in radiography; however, radiographers' interest in research has rarely been reported. This study sought to ascertain radiographers' opinions about radiography research and investigate their involvement in research activities in four Nordic countries.

This study was conducted in Denmark, Finland, Norway and Sweden. A study-specific questionnaire was developed in English and adapted to each language of the study sample, and the content and face validity of the adaptations were evaluated. An online tool was used to collect the study data. The questionnaire link was distributed in September 2019 to radiographers working in clinical settings in four Nordic countries (n=4572).

The overall response rate was 14% (n=662/4572). Research involvement was reported by 33% of the respondents; data collection was the main type of contribution. Radiographers who contributed to research were more likely to be male, have longer work experience, hold a master's or doctoral degree, work as managers and be employed in university hospitals. Nearly all agreed that radiography research is needed to promote the radiography profession and provide the evidence base for radiographic practice. However, only 14% were aware of the current research evidence regarding their professional field of specialisation, and 19% indicated that they developed current practices based on research evidence.

The findings indicate that, although radiographers had positive attitudes towards radiography research, their involvement in research and utilisation of research evidence in practice is low.

Strategies should be developed to improve knowledge and skills related to evidence-based practice and stimulate radiographers' engagement in research.
Strategies should be developed to improve knowledge and skills related to evidence-based practice and stimulate radiographers' engagement in research.
Few have examined the effects of psychosocial nutrition interventions targeting young adults, a population with low fruit and vegetable (FV) consumption. This study investigated the impact of nutrition interventions with psychosocial content on improving young adult FV intake.

This registered systematic review was guided by the Preferred Reported Items for Systematic Reviews and Meta-Analyses.

Searches on CINAHL, Embase, Medline PubMed, Ovid-Medline, PsychInfo, and Web of Science identified 4,113 records. Twenty-four randomized controlled trials were extracted. Eighteen studies found significant between-group differences in fruit and/or vegetable intake. Young adults with low income and racial-ethnic subgroups were underrepresented. A typology emerged as an organizing framework from the psychosocial intervention content. Interventions were anticipatory, socially engaged, a hybrid (anticipatory and socially engaged), or exposure-based. Studies also reported unintended consequences.

Significant between-ion. More research is needed to mitigate unintended consequences (boomerang effects) in which FV intake decreased postintervention or participants disengaged in activities intended to increase FV intake.
High-fat diet (HFD) had a complex impact on the myocardium and resulted in diastolic dysfunction and hypertension on left ventricular (LV) hypertrophy, which can cause cardiac remodeling. Two-dimensional speckle tracking echocardiography (2D-STE) provided deformation information of the LV, which had been reported to be valuable in identifying preclinical or subtle myocardial dysfunction. This study assessed whether 2D-STE can investigate the effect of HFD on cardiac function in mice.

Animals were grouped into HFD group and normal diet group according to whether they were feeding with HFD. We acquired the echocardiographic image and the mice weight before feeding, at 12th week and 20th week during feeding periods, compared the strain values and traditional echocardiographic measurements in both groups.

There was a stepwise increase in body weight both HFD group and normal group over time. There was a distinct statistics difference in body weight at the end of 12th and 20th week between the two groups (all P<0.05). There was no significant change in traditional echocardiographic measurements of left ventricle in the feeding periods. There was no obvious statistical difference in the strain values of the HFD mice compared to normal mice at 12th week (P>0.05); however, a significant decrease was observed in longitudinal strain (LS) and circumferential strain (CS) levels (P<0.05) at 20th week between the two groups.

Compared to the normal group, LS and CS values in the HFD mice were evidently decreased despite normal ejection fractions in both groups. 2D STE is sensitive to detect the LV altered cardiac mechanics associated with HFD and can provide valuable information for clinical intervention.
Compared to the normal group, LS and CS values in the HFD mice were evidently decreased despite normal ejection fractions in both groups. click here 2D STE is sensitive to detect the LV altered cardiac mechanics associated with HFD and can provide valuable information for clinical intervention.
In an effort to improve the clinical utility of the ICD-10, the WHO Working Group on the Classification of Sexual Disorders and Sexual Health recommended a new classification of Paraphilic Disorders in the ICD-11 to replace the ICD-10 section on Disorders of Sexual Preference. The proposed classification may have different implications for different countries.

To examine South African national laws and policies, within which Paraphilic Disorders are encountered, and to assess the implications of the new classification.

A South African working group - representing experts within the disciplines of criminal law, psychiatry, psychology, public health, and criminology - reviewed (i) national laws affected by reclassification, (ii) current practices in the psycho-legal assessment of sexual offenders, (iii) the implications of the reclassification for assessment and decision-making in forensic practice and other health settings, (iv) specific implications of the reclassification for diagnosis, and (v) implicae, highlighting the fact that the mere inclusion of a diagnosis in the ICD-11 does not necessarily have forensic relevance. Artz L, Swanepoel M, Nagdee M, et al. ICD-11 Paraphilic Disorders A South African Analysis of Its Utility in the Medico-Legal Context. J Sex Med 2021;18526-538.
It is recommended that the ICD-11 includes a cautionary statement for forensic use, highlighting the fact that the mere inclusion of a diagnosis in the ICD-11 does not necessarily have forensic relevance. Artz L, Swanepoel M, Nagdee M, et al. ICD-11 Paraphilic Disorders A South African Analysis of Its Utility in the Medico-Legal Context. J Sex Med 2021;18526-538.Surgical treatment of kidney stones has changed over the years. The use of Mini Percutaneous Nephrolithotomy (MiniPCNL) instrumentation is associated with a reduction of major complications but it lengthens the operative time (OT). This limit may be overcome by a semi-closed-circuit vacuum-assisted MiniPCNL system, characterized by a continuous inflow and a suction-controlled outflow. We present our initial experience in pediatric patients who underwent PCNL using a 12 Fr nephroscope and a 16-Fr-large nephrostomy sheath, equipped with a lateral arm connected to suction. We used Holmium laser lithotripsy and performed lapaxy by drawing back slowly the nephroscope inside the sheath until the opening of the lateral aspiration arm, without using other devices. The stone-free rate (SFR) was assessed at 4 weeks. We included 12 procedures in 8 patients with a median age of 119 months and a median weight of 27 Kg. The median OT was 108 min and the SFR was 80%. No intra-operative complications occurred, while minor post-operative complications occurred after 4/12 procedures.
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