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We encourage health service providers and patient advocates to be alert to the needs of individuals with ED and to take active measures to ensure access to appropriate evidence-based care both during and following the pandemic.
We explored college students' sexual pleasure using a new self-report measure, the Body, Emotions, Sensations, Touch/Trust (B.E.S.T.) Scale of Sexual Pleasure.
Data were from 3997 randomly sampled students with a partnered sexual experience.
Students completed an online survey about their most recent partnered sexual experience. Data was collected in January 2020.
Students find the nonphysical aspects of partnered sex (e.g., emotions, trust, connection with partners) as pleasurable as physical aspects (e.g., behaviors engaged and received, bodily sensations). Self-reported arousal, wantedness, and emotional intimacy were the strongest correlates of male, female, and transgender/gender non-binary students' sexual pleasure. Few sexual behaviors were associated with sexual pleasure and only one - cuddling for women - was associated with greater sexual pleasure. TGF beta inhibitor
Students find their partnered sexual experiences pleasurable. Students' sex may be more pleasurable when they feel ready for sex, desire se may be more pleasurable when they feel ready for sex, desire sex, and feel close to their partners.
This study aimed to evaluate the association of body composition with toxicity to first-line chemotherapy and three-year survival in women with ovarian adenocarcinoma.

We enrolled, in a retrospective cohort, 239 women treated with carboplatin and paclitaxel between 2008 and 2017. Pretreatment computed tomography scans were used to quantify skeletal muscle index (SMI), skeletal muscle radiodensity (SMD), and subcutaneous adipose tissue index (SATI). Chemotherapy doses, related toxicities, potential drug-drug interactions (DDI), and clinical variables were collected from medical records. Outcomes were the number of adverse events
grade 3 toxicity, toxicity-induced modification of treatment (TIMT), and three-year survival.

Average age was 56.3 years and 35.1% had myopenia. Almost 33% had TIMT and 51.3% presented any grade 3 toxicity. Potential severe DDI occurred in 48.1% of the patients and 65.1% died three years after the first treatment. The SMD and SATI below the median were independent predictors for the number of adverse events
grade 3 and TIMT. Also, SMD was the only body composition parameter able to predict reduced three-year survival. The SMI was not associated with any of the outcomes.

Fewer amounts of SATI and low SMD were associated with the occurrence of toxicity to chemotherapy, and the low SMD increased the risk of death in the three years after oncologic treatment.
Fewer amounts of SATI and low SMD were associated with the occurrence of toxicity to chemotherapy, and the low SMD increased the risk of death in the three years after oncologic treatment.Repeated visits to clinical trial sites inflict hardships on study participants, especially pregnant women. A newer trend is community-based follow-up for measurements, dosage, or monitoring, through technology or physical visits. We conducted a methodological experiment of performing "community-based physical follow-up" of participants of a trial, receiving facility-based diagnosis and pathogen-specific antibiotics for asymptomatic bacteriuria, guided by an optical-sensor-based rapid point-of-care test. We were able to retain 95.8% participants in the study. Here we describe challenges faced and socio-economic and gender issues encountered in this approach in a low-resource Indian scenario, to guide researchers world-wide for designing mother-friendly clinical trials.
To review the available literature on poppers maculopathy (PM).

Sixty-four patients (60 with bilateral and 4 with unilateral involvement), for a total of 124 eyes were reported in PubMed, Google Scholar and Embase. Patterns were analyzed according to country, age, gender, sexual orientation, HIV status, consumption habits, visual acuity at presentation (VAP), final visual acuity (VAF) and optical coherence tomography (OCT).

Most cases (110 eyes) of PM were reported in European countries and affected middle-aged men (only 8 eyes from female users). The median age was 38.7years (SD=10.5years). Final visual acuity (Median=0.8; Interquartile range 0.67-1) was higher than visual acuity at presentation (Median=0.67; Interquartile range 0.4-0.8). Many articles lack data on sexual orientation and HIV status as this is considered very personal information. One third of the eyes (40 eyes) developed PM after a single exposure. No significant differences were found between eyes that developed PM after a single expo not possible to make inferences about the possible implication of HIV drugs as cofactors for the development of this retinal toxicity.
This study is the first to obtain data on the prevalence of, contributors to, and supports required for, pandemic-related distress within the residential aged care sector in Australia. A nested mixed-methods approach was used to examine aged care leaders' opinions about the impact of COVID-19 on the mental health of aged care residents and staff.

A total of 288 senior staff of Australian residential aged care facilities (care managers, clinical care coordinators, and lifestyle team leaders; mean age= 52.7years,
= 10.3) completed an online survey between 10
September and 31
October 2020.

On average, nearly half of their residents experienced loneliness (41%) and a third experienced anxiety in response to COVID-19 (33%). The most frequently noted contributors to poor mental health among residents were restrictions to recreational outings and watching news coverage relating to COVID-19. Participants emphasized the need for increased access to counseling services and improved mental health training am clear intervention targets for supporting the sector. Clinicians can support residential aged care communities by providing on-site or telehealth counseling, and upskill and train residential aged care staff on how to respond to the emotional needs of residents in response to COVID-19.
The objective of this study was to assess the association of self-reported noise exposure and audiograms processed with ten algorithms proposed to quantify noise-induced hearing loss using receiver operating characteristic (ROC) curves.

Participants were placed into groups based on self-reported noise exposure. Self-reported noise exposure served as a predictor for noise-induced hearing loss (NIHL). Audiograms were analysed with ten algorithms The Guidelines, Brewster's Rules, two versions of military Noise-induced Hearing Loss, the Bulge Depth, the age-adjusted 8 kHz threshold and four versions of a new algorithm called the Adjusted Notch Depth (AND). The area under the ROC curves were calculated for each algorithm.

Data were collected from three cycles of the National Health and Nutrition Examination Survey.

Only one version the AND significantly identified those with self-reported noise exposure with an area under the curve of 0.562.

The association between the AND and self-reported noise exposure was marginally better than the previous algorithms in identifying those with self-reported noise exposure. These findings do not support using puretone thresholds for identifying those with NIHL in a cross-sectional research study without stratifying the participants. More research is needed to determine how the AND can be applied to stratified designs.
The association between the AND and self-reported noise exposure was marginally better than the previous algorithms in identifying those with self-reported noise exposure. These findings do not support using puretone thresholds for identifying those with NIHL in a cross-sectional research study without stratifying the participants. More research is needed to determine how the AND can be applied to stratified designs.
The aim of this study was to assess to what extent
measures of listening effort (task-evoked pupil dilation, verbal response time [RT], and self-rating) could be sensitive to auditory and cognitive manipulations in a speech perception task. The study also aimed to explore the possible relationship between RT and pupil dilation.

A within-group design was adopted. All participants were administered the Matrix Sentence Test in 12 conditions (signal-to-noise ratios [SNR] of -3, -6, -9 dB; attentional resources focussed
divided; spatial priors present
absent).

Twenty-four normal-hearing adults, 20-41 years old (
 = 23.5), were recruited in the study.

A significant effect of the SNR was found for all measures. However, pupil dilation discriminated only partially between the SNRs. Neither of the cognitive manipulations were effective in modulating the measures. No relationship emerged between pupil dilation, RT and self-ratings.

RT, pupil dilation, and self-ratings can be obtained simultaneously when administering speech perception tasks, even though some limitations remain related to the absence of a retention period after the listening phase. The sensitivity of the three measures to changes in the auditory environment differs. RTs and self-ratings proved most sensitive to changes in SNR.
RT, pupil dilation, and self-ratings can be obtained simultaneously when administering speech perception tasks, even though some limitations remain related to the absence of a retention period after the listening phase. The sensitivity of the three measures to changes in the auditory environment differs. RTs and self-ratings proved most sensitive to changes in SNR.To enhance access to evidence-based treatment it is increasingly important to evaluate scalable virtual programs that support the needs of those struggling with disordered eating. This study described a scientifically grounded, trauma-informed framework known as Body Trust,® and aimed to pilot test the preliminary effectiveness and mechanisms of change in a Body Trust® program to improve disordered eating. Using quality outcomes data, we examined 70 mostly white (87%) female-identifying (97%) individuals enrolled in a 6-module online program based in the Body Trust® framework (Mage = 45.5 ±10.9; MBMI = 33.7 ±8.0). Putative mediators included traumatic stress, internalized weight stigma, and body shame. Outcomes were objective and subjective binge episodes, overvaluation of weight and shape, and eating concerns. Generalized estimating equations were applied to determine pre-to-post changes. We applied Montoya's MEMORE macro, the joint-significance test, and calculated 95% Monte Carlo confidence intervals to assess mediation. Significant pre-to-post improvements with medium to large effect sizes were detected for all outcomes and mediators (ps less then .008). All hypothesized mechanisms supported mediation. Using the Body Trust® framework shows early promise for alleviating disordered eating symptoms through targeting traumatic stress, body shame, and internalized weight stigma. Given the program's use of mindfulness techniques, future research should test target mechanisms like interoception.
(in alphabetical order of first author)The following abstracts were accepted for presentation at the Stroke Society of Australasia Annual Scientific Meeting of 2021. We thank the authors for their contribution to the meeting and the Scientific Committee for their valuable input into the program.Erin Godecke and Nawaf YassiScientific Committee Co-Chairs.
(in alphabetical order of first author)The following abstracts were accepted for presentation at the Stroke Society of Australasia Annual Scientific Meeting of 2021. We thank the authors for their contribution to the meeting and the Scientific Committee for their valuable input into the program.Erin Godecke and Nawaf YassiScientific Committee Co-Chairs.
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