Notes

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a high safety profile. However, intranasal administration results in more satisfactory sedation, less postoperative agitation upon awakening, and reduces postoperative cognitive dysfunction.
This study aimed to investigate the clinical efficacy of ultrasonic emulsification plus IOL implantation in patients with primary angle-closure glaucoma and cataract.

The clinical data of 81 patients (91 eyes) with primary angle-closure glaucoma comorbid with cataract in our hospital were retrospectively analyzed and divided into two groups based on surgical modality. Group A (n=40, 45 eyes) underwent trabeculectomy and group B (n=41, 46 eyes) underwent ultrasonic emulsification and IOL implantation. The success rate, best corrected visual acuity, intraocular pressure, anterior chamber depth, anterior chamber angle, visual field, cornea's endothelial cell count, complications, and patient satisfaction were compared between the two groups.

The surgical success rate in group B was 97.83%, significantly higher than 86.67% in group A (
< 0.05); Compared with group A, group B had higher best-corrected visual acuity and lower intraocular pressure (
< 0.05) as well as higher central and peripheral ane, increasing the atrial angle, and improving visual field defects. It is also with high safety, but has little effect on cornea's endothelial cell count.
To compare the effect of acute hypervolemic hemodilution and conventional infusion in prostate cancer patients undergoing laparoscopic radical prostatectomies.

A total of 87 patients with prostate cancer who underwent laparoscopic radical prostatectomies in our hospital were retrospectively analyzed. The patients were randomly divided into a control group (the CNG, n=43, conventional infusion) and an observation group (the OG, n=44, acute hypervolemic hemodilution). Blood gas analyses were performed at different time points, and the patients' cognitive dysfunction was evaluated.

The intraoperative blood transfusion rates of the OG and the CNG were 11.36% and 30.23%. The average intraoperative blood transfusions in the OG and the CNG were (315.46±24.49) ml and (486.95±42.17) ml (
< 0.05). The CVP and JVP levels in the OG and the CNG at T2 and T3 were significantly higher than the levels at T0 (
< 0.05). The Hb levels of the CNG at T3 and T4 were lower than they were at T0 (
< 0.05), and the Hb level in the OG at T4 was lower than it was at T1 (
< 0.05). The Hb levels in the CNG at T3 and T4 were lower than they were at T1 (
< 0.05), and the Hb levels in the OG at T1 and T2 were lower than they were in the CNG (
< 0.05). The MMSE cognitive function scores were lower than the scores recorded on the day before the operations (
< 0.05).

Acute hypervolemic hemodilution in laparoscopic radical prostatectomy patients can maintain their hemodynamics in a stable state, help reduce blood transfusion, improve the oxygen supply to the brain tissue to maintain the supply and demand balance, and reduce the impact on the patients' cognitive function.
Acute hypervolemic hemodilution in laparoscopic radical prostatectomy patients can maintain their hemodynamics in a stable state, help reduce blood transfusion, improve the oxygen supply to the brain tissue to maintain the supply and demand balance, and reduce the impact on the patients' cognitive function.
To explore the effect of pemetrexed on the efficacy, toxic reaction, and survival rate of patients with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistant moderate to advanced lung cancer.

A total of 86 patients with EGFR-TKI resistant moderate and advanced lung cancer in our hospital were divided by therapeutic drugs into a control group (39 patients) and pemetrexed group (47 patients). Differences in general data, clinical efficacy, immunoglobulin expression, tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) levels, tumor markers, toxic reaction, and survival rate between the two groups were analyzed.

Similar expression levels of carcinoembryonic antigen, IL-6, carbohydrate antigen 125, TNF-α, carbohydrate antigen 153 and immunoglobulin were found in the control group and pemetrexed group before treatment (all P>0.05). Expression levels of the above indicators in all patients decreased one month after the end of treatment, and levels of immunoglobulin, inflammatory factors, and tumor markers in the control group were higher than those in the pemetrexed group (all P<0.05). Similar incidence rates of toxic reactions were shown in the two groups (P>0.05). Twelve months after the end of treatment, one-year survival rate was significantly higher in the pemetrexed group than in the control group (χ
=3.332, P=0.042).

Pemetrexed can significantly improve the clinical efficacy in patients with EGFR-TKI resistant lung cancer, decrease the expression of inflammatory factors, tumor markers, and immunoglobulin in serum, has few side effects on the body, and prolongs the long-term survival rate.
Pemetrexed can significantly improve the clinical efficacy in patients with EGFR-TKI resistant lung cancer, decrease the expression of inflammatory factors, tumor markers, and immunoglobulin in serum, has few side effects on the body, and prolongs the long-term survival rate.
The aim of this study was to compare the effectiveness of central venous pressure (CVP) versus stroke volume variation (SVV) to guide fluid management in renal transplantation.

The clinical data of 97 patients who underwent allogeneic renal transplantation in our hospital were collected retrospectively. Based on the method of intraoperative infusion monitoring, they were divided into group A, which received guided fluid management by monitoring CVP, and group B which received guided fluid management by monitoring SVV. The changes in intraoperative hemodynamic indicators, urine volume, blood loss, and total blood transfusion volume, total fluid volume, urine output at different time points after surgery, renal function indicators, blood purification rate, length of stay, and postoperative complications were compared between the two groups.

CVP values at T1 (5 min before surgery), T2 (external iliac vein obstruction), T3 (establishment of vessel access), and T4 (end of surgery) in group B were higher thanry.
Compared with CVP, fluid management guided by monitoring SVV during renal transplantation can reduce intraoperative fluid volume, optimize the renal perfusion, reduce postoperative blood purification, and facilitate postoperative recovery.
To investigate the effect of early home-based cardiac rehabilitation (CR) exercise on the prognosis of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI).

The clinical data of 115 patients with AMI in our hospital were collected retrospectively. All patients underwent PCI and were divided into group A (n=57) and group B (n=58) according to postoperative intervention. Patients in group A only received routine rehabilitation guidance, while those in group B received early home-based CR exercise. The incidence of postoperative complications, cardiac function index, 6-minute walking distance (6MWD), cardiac antioxidant index, exercise endurance index and quality of life score were compared between the two groups before and after intervention.

Compared with those in group B, patients in group A showed a lower incidence of postoperative complications (17.54% vs. 3.45%,
<0.05). After intervention, group A had lower left ventricular ejection fraction (LVEF), left ventricular end systolic diameter (LVESD) and left ventricular end diastolic diameter (LVEDD), longer 6MWD, higher total antioxidant capacity (T-AOC) and superoxide dismutase (SOD), lower malonaldehyde (MAD), higher exercise duration (ED), anaerobic threshold (AT) and VO
and higher scores of quality of life than group B (
<0.05).

Early home-based CR exercise in patients with AMI after PCI can improve cardiac function, reduce the incidence of postoperative complications as well as enhance cardiac antioxidant capacity, exercise ability and quality of life.
Early home-based CR exercise in patients with AMI after PCI can improve cardiac function, reduce the incidence of postoperative complications as well as enhance cardiac antioxidant capacity, exercise ability and quality of life.
The purpose of the study was to analyze the ultrasound findings and imaging features of patients with special types of ectopic pregnancy.

The ultrasound findings of 40 patients with special types of ectopic pregnancy in our hospital were retrospectively analyzed.

Among 40 patients, there were 17 cases of corneal pregnancy, 12 cases of cervical pregnancy, 8 cases of uterine scar pregnancy, and 3 cases of incomplete abortion confirmed by operation and pathology. The accuracy rate of ultrasound findings in the diagnosis of 40 special types of ectopic pregnancy was 77.50%, with a consistency rate of 70.59% for cornual pregnancy, 83.33% for cervical pregnancy, 100.00% for cesarean scar pregnancy and 33.33% for incomplete abortion. There were 9 misdiagnoses in ultrasound diagnosis, including 5 misdiagnoses of angular pregnancy (misdiagnosed as 4 cases of tubal interstitial pregnancy and 1 case of trophoblastic tumor), 2 misdiagnoses of cervical pregnancy (misdiagnosed as incomplete abortion), and 2 misdiagnoses of incomplete abortion (misdiagnosed as isthmus pregnancy). DNA Repair inhibitor There was no misdiagnosed case of cesarean scar pregnancy.

Ultrasound findings have some value in the diagnosis of specific types of ectopic pregnancy and can help identify different types of ectopic pregnancy. Transabdominal ultrasound and transvaginal ultrasound should be clinically combined to obtain more information for diagnosis.
Ultrasound findings have some value in the diagnosis of specific types of ectopic pregnancy and can help identify different types of ectopic pregnancy. Transabdominal ultrasound and transvaginal ultrasound should be clinically combined to obtain more information for diagnosis.
To explore the effect of an evidence-based bundled care model in patients with dysphagia after severe traumatic brain injury (TBI).

This is a prospective randomized controlled study. A total of 60 patients with dysphagia after severe TBI (traumatic brain injury) admitted to the Department of Rehabilitation Medicine were selected and randomly divided into the test group (n=30) and the control group (n=30). Patients in the control group received routine care in the Department of Rehabilitation Medicine, while patients in the test group received evidence-based bundled care on the basis of the treatment of the control group. The improvement of swallowing function (dye test in comatose patients), oral hygiene, and nutritional risk was assessed in both groups. The incidence of adverse events such as aspiration and aspiration pneumonia, as well as the length and costs of hospitalization were compared between the two groups.

Compared with patients in the control group, swallowing function of patients in the testes postoperative rehabilitation of patients.
To investigate the clinical value of carboprost tromethamine injection combined with modified B-lynch suture and carboprost methylate suppositories in the treatment of placenta previa parturients with postpartum hemorrhage after cesarean section.

A total of 102 parturients with placenta previa and postpartum hemorrhage after cesarean section in our hospital were selected as the study subjects, and they were divided into Group A (carboprost tromethamine injection combined with modified B-lynch suture, n=35), Group B (carboprost methylate suppositories, n=34), and Group C (carboprost tromethamine injection, n=33) in accordance with a random number table. The amounts of hemorrhaging and clinical indices in the three groups were recorded, and the rescue effects were compared among the three groups.

The amount of hemorrhaging in Group A was significantly lower than that in Groups B and C during surgery and 24 h after surgery (
< 0.05). There were markedly improved clinical indices in Groups A, B and C, showing statistical significance (
< 0.
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