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Constitutionnel Analysis regarding Orf Trojan Bcl-2 Homolog ORFV125 Interactions using BH3-Motifs via BH3-Only Meats The puma company and also Hrk.
The implementation of control algorithms oriented to robotic assistance and rehabilitation tasks for people with motor disabilities has been of increasing interest in recent years. However, practical implementation cannot be carried out unless one has the real robotic system availability. To overcome this drawback, this article presents the development of an interactive virtual reality (VR)-based framework that allows one to simulate the execution of rehabilitation tasks and robotic assistance through a robotic standing wheelchair. The virtual environment developed considers the kinematic and dynamic model of the standing human-wheelchair system with a displaced center of mass, since it can be displaced for different reasons, e.g., bad posture, limb amputations, obesity, etc. The standing wheelchair autonomous control scheme has been implemented through the Full Simulation (FS) and Hardware in the Loop (HIL) techniques. Finally, the performance of the virtual control schemes has been shown by means of several experiments based on robotic assistance and rehabilitation for people with motor disabilities.Ecological environments research helps to assess the impacts on forests and managing forests. The usage of novel software and hardware technologies enforces the solution of tasks related to this problem. In addition, the lack of connectivity for large data throughput raises the demand for edge-computing-based solutions towards this goal. Therefore, in this work, we evaluate the opportunity of using a Wearable edge AI concept in a forest environment. For this matter, we propose a new approach to the hardware/software co-design process. We also address the possibility of creating wearable edge AI, where the wireless personal and body area networks are platforms for building applications using edge AI. Finally, we evaluate a case study to test the possibility of performing an edge AI task in a wearable-based environment. Thus, in this work, we evaluate the system to achieve the desired task, the hardware resource and performance, and the network latency associated with each part of the process. Through this work, we validated both the design pattern review and case study. In the case study, the developed algorithms could classify diseased leaves with a circa 90% accuracy with the proposed technique in the field. This results can be reviewed in the laboratory with more modern models that reached up to 96% global accuracy. The system could also perform the desired tasks with a quality factor of 0.95, considering the usage of three devices. Finally, it detected a disease epicenter with an offset of circa 0.5 m in a 6 m × 6 m × 12 m space. These results enforce the usage of the proposed methods in the targeted environment and the proposed changes in the co-design pattern.Convolution operations have a significant influence on the overall performance of a convolutional neural network, especially in edge-computing hardware design. In this paper, we propose a low-power signed convolver hardware architecture that is well suited for low-power edge computing. The basic idea of the proposed convolver design is to combine all multipliers' final additions and their corresponding adder tree to form a partial product matrix (PPM) and then to use the reduction tree algorithm to reduce this PPM. As a result, compared with the state-of-the-art approach, our convolver design not only saves a lot of carry propagation adders but also saves one clock cycle per convolution operation. Moreover, the proposed convolver design can be adapted for different dataflows (including input stationary dataflow, weight stationary dataflow, and output stationary dataflow). According to dataflows, two types of convolve-accumulate units are proposed to perform the accumulation of convolution results. The results show that, compared with the state-of-the-art approach, the proposed convolver design can save 15.6% power consumption. Furthermore, compared with the state-of-the-art approach, on average, the proposed convolve-accumulate units can reduce 15.7% power consumption.This paper describes issues of leakage localization in liquid transmission pipelines. It focuses on the standard leak localization procedure, which is based on the calculation of pressure gradients using pressure measurements captured along a pipeline. The procedure was verified in terms of an accuracy and uncertainty assessment of the resultant coordinate of a leak spot. An important aim of the verification was to assess the effectiveness of the procedure in the case of localization of low intensity leakages with a level of 0.25-2.00% of the nominal flow rate. An uncertainty assessment was carried out according to the GUM convention. The assessment was based on the metrological characteristics of measuring devices and measurement data obtained from the laboratory model of the pipeline.The growth of the automated welding sector and emerging technological requirements of Industry 4.0 have driven demand and research into intelligent sensor-enabled robotic systems. The higher production rates of automated welding have increased the need for fast, robotically deployed Non-Destructive Evaluation (NDE), replacing current time-consuming manually deployed inspection. This paper presents the development and deployment of a novel multi-robot system for automated welding and in-process NDE. Full external positional control is achieved in real time allowing for on-the-fly motion correction, based on multi-sensory input. The inspection capabilities of the system are demonstrated at three different stages of the manufacturing process after all welding passes are complete; between individual welding passes; and during live-arc welding deposition. The specific advantages and challenges of each approach are outlined, and the defect detection capability is demonstrated through inspection of artificially induced defects. The developed system offers an early defect detection opportunity compared to current inspection methods, drastically reducing the delay between defect formation and discovery. This approach would enable in-process weld repair, leading to higher production efficiency, reduced rework rates and lower production costs.It is important to find objective biomarkers for evaluating gait in Parkinson's Disease (PD), especially related to the foot and lower leg segments. Foot-switch signals, analyzed through Statistical Gait Analysis (SGA), allow the foot-floor contact sequence to be characterized during a walking session lasting five-minutes, which includes turnings. Gait parameters were compared between 20 PD patients and 20 age-matched controls. PDs showed similar straight-line speed, cadence, and double-support compared to controls, as well as typical gait-phase durations, except for a small decrease in the flat-foot contact duration (-4% of the gait cycle, p = 0.04). However, they showed a significant increase in atypical gait cycles (+42%, p = 0.006), during both walking straight and turning. A forefoot strike, instead of a "normal" heel strike, characterized the large majority of PD's atypical cycles, whose total percentage was 25.4% on the most-affected and 15.5% on the least-affected side. Moreover, we found a strong correlation between the atypical cycles and the motor clinical score UPDRS-III (r = 0.91, p = 0.002), in the subset of PD patients showing an abnormal number of atypical cycles, while we found a moderate correlation (r = 0.60, p = 0.005), considering the whole PD population. Atypical cycles have proved to be a valid biomarker to quantify subtle gait dysfunctions in PD patients.Induction machines (IMs) are one of the main sources of mechanical power in many industrial processes, especially squirrel cage IMs (SCIMs), due to their robustness and reliability. Their sudden stoppage due to undetected faults may cause costly production breakdowns. One of the most frequent types of faults are cage faults (bar and end ring segment breakages), especially in motors that directly drive high-inertia loads (such as fans), in motors with frequent starts and stops, and in case of poorly manufactured cage windings. A continuous monitoring of IMs is needed to reduce this risk, integrated in plant-wide condition based maintenance (CBM) systems. Diverse diagnostic techniques have been proposed in the technical literature, either data-based, detecting fault-characteristic perturbations in the data collected from the IM, and model-based, observing the differences between the data collected from the actual IM and from its digital twin model. In both cases, fast and accurate IM models are needed to develop and optimize the fault diagnosis techniques. On the one hand, the finite elements approach can provide highly accurate models, but its computational cost and processing requirements are very high to be used in on-line fault diagnostic systems. On the other hand, analytical models can be much faster, but they can be very complex in case of highly asymmetrical machines, such as IMs with multiple cage faults. In this work, a new method is proposed for the analytical modelling of IMs with asymmetrical cage windings using a tensor based approach, which greatly reduces this complexity by applying routine tensor algebra to obtain the parameters of the faulty IM model from the healthy one. This winding tensor approach is explained theoretically and validated with the diagnosis of a commercial IM with multiple cage faults.Interferometric inverse synthetic aperture radar (InISAR) has received significant attention in three-dimensional (3D) imaging due to its applications in target classification and recognition. The traditional two-dimensional (2D) ISAR image can be interpreted as a filtered projection of a 3D target's reflectivity function onto an image plane. Such a plane usually depends on unknown radar-target geometry and dynamics, which results in difficulty interpreting an ISAR image. Using the L-shape InISAR imaging system, this paper proposes a novel 3D target reconstruction algorithm based on Dechirp processing and 2D interferometric ISAR imaging, which can jointly estimate the effective rotation vector and the height of scattering center. In order to consider only the areas of the target with meaningful interferometric phase and mitigate the effects of noise and sidelobes, a special cross-channel coherence-based detector (C3D) is introduced. Compared to the multichannel CLEAN technique, advantages of the C3D include the following (1) the computational cost is lower without complex iteration and (2) the proposed method, which can avoid propagating errors, is more suitable for a target with multi-scattering points. Moreover, misregistration and its influence on target reconstruction are quantitatively discussed. Theoretical analysis and numerical simulations confirm the suitability of the algorithm for 3D imaging of multi-scattering point targets with high efficiency and demonstrate the reliability and effectiveness of the proposed method in the presence of noise.Ligament balancing during total knee arthroplasty (TKA) often relies on subjective surgeon experience. Although instrumented tibial trays facilitate an objective assessment of intraoperative joint balance through quantification of intra-articular joint loads, postoperative clinical assessment of joint balance relies on passive stress tests quantifying varus-valgus joint laxity. This study aimed at correlating the intraoperative and postoperative metrics used to assess joint balance while also comparing joint loads obtained during passive assessment and active functional motions. learn more Four experienced surgical fellows were assigned a fresh-frozen lower limb each to plan and perform posterior-stabilised TKA. An instrumented tibial insert measured intraoperative intra-articular loads. Specimens were then subjected to passive flexion-extension, open-chain extension, active squatting, and varus-valgus laxity tests on a validated knee simulator. Intra-articular loads were recorded using the instrumented insert and tibiofemoral kinematics using an optical motion capture system.
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