Notes

Down-regulation involving circITCH helps bring about osteosarcoma growth and effectiveness against doxorubicin via the miR-524/RASSF6 axis.
However, this decrease is not specific for nephropathy and may be due to other accompanying chronic diseases. Key Words Hypertension, Hypertensive nephropathy, Elabela.
The plasma levels of Elabela were lower in the case of hypertension, independent of nephropathy. However, this decrease is not specific for nephropathy and may be due to other accompanying chronic diseases. Key Words Hypertension, Hypertensive nephropathy, Elabela.
To investigate whether HALP score [hemoglobin, albumin, lymphocyte (LY), platelet] can predict weight loss in patients undergoing sleeve gastrectomy.

A cohort study.

Department of General Surgery, Balıkesir University, Turkey from July 2019 to July 2020.

One-year data of 64 patients, who underwent sleeve gastrectomy due to obesity were included for the analysis. The cut-off value of HALP score was calculated to be 41.2971. Those below the cut-off value were classified into Group 1 (low HALP score) and those above it were classified into Group 2 (high HALP score). Preoperative and postoperative body mass index (BMI), hemotologic parameters, platelet/LY ratios (PLR), and neutrophil/LY ratios (NLR), were compared. According to the percentage of excess BMI loss, patients were divided into 3 groups Group A (≤40%), Group B (40%-60%), Group C (≥60%).

The decrease in postoperative BMI was significantly high in Group 2 (p<0.001). There was a significant difference between the groups in terms of percentage change of hemoglobin (p=0.012). The increase in postoperative LY value and decrease in postoperative PLR value were significantly high in Group 1 (p=0.019, p=0.003). Furthermore, patient distribution was significantly different among groups A, B, and C (p <0.001). Comparison of groups showed a significant difference between groups A and B and between groups A and C, but not between groups B and C (p=0.006, p<0.001, and p=0.192, respectively).

In patients with high HALP scores, the rate of weight loss was higher, and most of their laboratory parameters were improved compared to those patients with low HALP scores. Key Words Body mass index, Sleeve gastrectomy, obesity, Weight loss, HAIP score.
In patients with high HALP scores, the rate of weight loss was higher, and most of their laboratory parameters were improved compared to those patients with low HALP scores. Key Words Body mass index, Sleeve gastrectomy, obesity, Weight loss, HAIP score.
To evaluate the value of apparent diffusion coefficient (ADC) for the differentiation of histological subtypes in endometrial cancer, and to assess if ADC values correlate with histopathological parameters.

Descriptive study.

Department of Radiology, Faculty of Medicine, Ondokuz Mayis University between January 2016 and December 2019.

Eighty-three patients (mean age 60.28 ± 9.07) with endometrial cancer underwent diffusion-weighted imaging (DWI) at 3T before surgery. The mean ADC (ADCmean) and minimum ADC (ADCmin) values of the tumours were assessed to predict histological subtype of endometrial cancer, grade of tumour, presence of myometrial invasion, lower uterine segment involvement, cervical involvement, lymphovascular invasion, and lymph node metastasis.

Sixty patients (72.3%) were diagnosed with endometrioid carcinoma, and 23 patients (27.7%) were diagnosed with non-endometrioid carcinoma. The median ADCmean/ADCmin of endometrioid and non-endometrioid tumours were 0.72/0.58 ×10-3 mm2/s and 0.8icantly lower ADC values compared to low-grade ones. Key Words Endometrial cancer, Diffusion-weighted MRI, Apparent diffusion coefficient, Prognostic factors, Histological grade.
To investigate standard modifiable cardiovascular risk factors (SMuRFs) and prognosis of patients with acute coronary syndrome (ACS) aged 50 years or younger.

An observational study.

Eleven general hospitals in Chengdu, Sichuan Province, China, from January 2017 to June 2019.

Patients with ACS were stratified into younger group (≤50 years) and older group (>50 years). The baseline characteristics and prognosis were compared for two groups. Survival analysis was used to assess the long-term prognosis.

Among a total of 1982 ACS patients, 322 (16.2%) were of ≤50 years. Compared with older patients, younger patients were more likely to have at least one SMuRFs (90.0% vs. 84.3%, p=0.013). The younger group had a higher prevalence of smoking (62.8% vs. 34.1%, p <0.001) and hypercholesterolemia (36.2% vs. 23.4%, p <0.001) compared with the older group. Younger male patients were more likely to have at least one SMuRFs than younger female patients (91.6% vs. 74.1%, p = 0.011). After the follow-up of 15 (10, 22) months, the cumulative rates of major adverse cardiovascular and cerebrovascular events (MACCE) of the younger patients were significantly lower than those in the older patients [hazard ratio (HR) 0.2661, 95% confidence interval (CI) 0.1932 - 0.3665, p <0.001].

Younger patients with ACS were more likely to have at least one SMuRFs; and were likely to have a better prognosis than older patients. Key Words Coronary artery disease, Acute coronary syndrome, Middle aged, Risk factors, Prognosis.
Younger patients with ACS were more likely to have at least one SMuRFs; and were likely to have a better prognosis than older patients. Key Words Coronary artery disease, Acute coronary syndrome, Middle aged, Risk factors, Prognosis.Null.
Dental healthcare workers are exposed to various infectious agents that may present an occupational risk. Although vaccinations rank among the most cost-effective health measures, vaccine hesitancy is present among healthcare workers.

A structured anonymous questionnaire was completed by 1111 dental healthcare workers - dentists, dental hygienists, prophylaxis assistants, dental assistants, dental technicians, and dental students. Demographic data and immunisation status, either by vaccination or by immunity after disease, were collected. Additionally, employers and employees were asked about their current workplace vaccination policy, including questions about information provided on the risk of hepatitis B (HBV) infection, whether HBV vaccination was compulsory and who paid for compulsory vaccinations.

The overall response rate was 55.7%. Approximately half of the participants were dentists; only 17 technicians completed the questionnaire. The most common immunisation was for HBV (94.7% of participantated against HBV, but they were particularly hesitant about the seasonal influenza vaccination. As a considerable number of participants was unaware of their immunisation status, more comprehensive information on infectious diseases, vaccination and prevention is essential.
The Swiss dental healthcare workers participating in this study had a medium level of awareness towards vaccinations. Almost all participants were vaccinated against HBV, but they were particularly hesitant about the seasonal influenza vaccination. As a considerable number of participants was unaware of their immunisation status, more comprehensive information on infectious diseases, vaccination and prevention is essential.The historical artifacts displayed in the Museum of Western study on Chinese Medicine at Yunnan University of Chinese Medicine came from a variety of Chinese medical schools in America and European countries. They are in the memorial galleries for some well-known figures, such as George Soulié de Morant (Su Lie), Jacques-André Lavier (La Wei Ai), Felix Mann (Man Fu Li) and Manfred Porkert (Man Xi Bo), representing the development and status of respective Chinese medical schools in America and European countries. The displayed artifacts are nearly 3,000 photos, manuscripts, documents and more than 500 hours of audiovisual materials, including instruments for acupuncture and moxibustion, books, passports, letters and even supplies for their life. The displayed artifacts demonstrate the process and the access of people in the western societies to know, learn and take use of Chinese medicine.San Xiao Lun is a posthumous manuscript by Liu Wansu. It discussed the etiology, pathogenesis and therapeutic principles of diabetes with special prescriptions for it. Most references in this book came from the works of Liu Wansu himself and some of them came from the works of other sources, such as The Internal Cannon of Medicine. It can be seen that it was a book with Liu Wansu's rethinking and summerising about diabetes after he completed his other works. DAPK3 inhibitor HS148 San Xiao Lun was first published in Ru Men Shi Qin in the Jin Dynasty. It was also cited by Yi Fang Lei Ju in Korea in 1445. It was fully recorded and published in Ru Men Shi Qin in the Wanli Period in the Ming Dynasty and therefore, became the basic version of the current one. After that, it envolved into Si Ku Quan Shu. In the end of the Qing Dynasty, this book was published independently with the comments by Zhou Xuehai, being one of the books in the Zhous' Series Medical Books(Zhou Shi Yi Xue Cong Shu).The Medical Theory (Yi Shuo) and The Mengqiu of Famous Medical Doctors in the Past Dynasties (Li Dai Ming Yi Meng Qiu) are two medical books that originated in the Song Dynasty. The two books quoted from The List of Medical Doctors (Ming Yi Lu) many times while the author and the issue time of The List of Medical Doctors (Ming Yi Lu) has not been clearly known up to know. It was found that there were 25 quotations in The Medical Theory (Yi Shuo) and 31 quotations in The Mengqiu of Famous Medical Doctors in the Past Dynasties (Li Dai Ming Yi Meng Qiu) from The List of Medical Doctors (Ming Yi Lu). The contents quoted in the two books are also found in The Mysterious Medical List (Shen Mi Ming Yi Lu) written by Dang Yongnian in the Song Dynasty. In this sense, it can be inferred that The List of Medical Doctors (Ming Yi Lu) mentioned above should be The Mysterious Medical List (Shen Mi Ming Yi Lu).Smallpox was believed afferent before the Sui Dynasty. Some relatively accurate descriptions about smallpox were found in the Sui and Tang Dynasties. Smallpox was recognized as a severe infectious disease caused by pathogenic heat by the observation of its symptoms and appearance. It was believed that smallpox was caused by the heat accumulation in the Zang-Fu organs in the early period of the North Song Dynasty. After that, it was believed caused by the fetus ingesting the filthy liquid from the mother as the prototype of the fetal poison theory. This means that ancient Chinese physicians were able to distinguish the differences among chickenpox, measles and smallpox at that time. The exogenous theory of fetal poison became the mainstream in the Ming and Qing dynasties. Smallpox, therefore, was confirmed not to be re-infected after once infection, and was specifically described with the symptoms and the precise prognosis. It can be seen that the understanding of smallpox by ancient Chinese physicians developed with time, and these understandings opened a way for the invention of the human pox vaccination.At the beginning of the New China, the first National Health Administration Conference and the first National Health Conference established the health administration policies of the New China, but ignored the training of Chinese medicine successors. After 1954, the policy towards Chinese medicine changed gradually. In 1956, the Ministry of Health issued the Instructions on Carrying out the Work of Apprentices with Chinese Medicine, and developed the National Plan for Apprentices with Chinese Medicine from 1956 to 1962 (Draft). Although their initial implementation did not go smoothly, it was still one of the important policy measures to train and cultivate new practitioners of traditional Chinese medicine (TCM) and ensure TCM successors in the New China.
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