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Visual and Well-designed Connection between 2-Stage As opposed to 3-Stage Paramedian Brow Flap Techniques: The 9-Year Marketplace analysis Study Together with Prospectively Accumulated Files.
Reducing particle size in supported metal catalysts to single-atom level isolates the active metal sites and maximizes the atomic utilization efficiency. However, the large inter-atom distance, particularly in low-loading single-atom catalyst (SAC), is not favorable for a complex reaction where two (or more) reactants have to be activated. A key question is how to control the inter-atom distances to promote dinuclear-type coactivation at the adjacent metal sites. Here, it is reported that reducing the average inter-atom distance of copper SACs supported on carbon nitride (C3 N4 ) to 0.74 ± 0.13 nm allows these catalysts to exhibit a dinuclear-type catalytic mechanism in the nitrile-azide cycloaddition. Operando X-ray absorption fine structure study reveals a dynamic ligand exchange process between nitrile and azide, followed by their coactivation on dinuclear Cu SAC sites to form the tetrazole product. This work highlights that reducing the nearest-neighbor distance of SAC allows the mechanistic pathway to diversify from single-site to multisite catalysis.Historically, studies of childhood and adult resilience have typically focused on adaptation to chronic life adversities, such as poverty and maltreatment, or isolated and potentially traumatic events, such as bereavement and serious illness. Here, we present a complementary view and suggest that stressors experienced in daily life may also forecast individual health and well-being. We argue that daily process approaches that incorporate intensive sampling of individuals in natural settings can provide powerful insights into unfolding adaptational processes. In making this argument, we review studies that link intraindividual dynamics with diverse health-related phenomena. Findings from this research provide support for a multiple-levels-analysis perspective that embraces greater unity in pivotal resilience constructs invoked across childhood and adult literatures. Drawing on insights and principles derived from life-span theory, we conclude by outlining promising directions for future work and considering their broader implications for the field of resilience.Chondroid syringoma is a rare benign adnexal tumor and tends to occur in the head and neck region. Involvement in the axilla is very unusual, and the differential diagnosis of such presentations includes lymphadenopathy and cyst. Fine needle aspiration cytology (FNAC) is a very useful tool for the diagnosis of chondroid syringoma. The characteristic feature of chondroid syringoma in cytology is the presence of distinct biphasic cell populations of epithelial and myoepithelial cells in the chondromyxoid stroma. If the typical biphasic cellular and chondromyxoid stromal elements are not visible in smears, it may be misdiagnosed in cytology. Here, we describe a case of axillary chondroid syringoma that was initially misdiagnosed as a metastatic carcinoma by FNAC. Although chondroid syringoma rarely occurs in the axilla, it should be included among the differential diagnoses of an axillary mass. ACY-738 Cytopathologists need to discern the unique cytological features of chondroid syringoma and avoid misdiagnosis for prompt management of the patient.Homologous centromeres compete for segregation to the secondary oocyte nucleus at female meiosis I. Centromeric repeats also compete with each other to populate centromeres in mitotic cells of the germline and have become adapted to use the recombinational machinery present at centromeres to promote their own propagation. Repeats are not needed at centromeres, rather centromeres appear to be hospitable habitats for the colonization and proliferation of repeats. This is probably an indirect consequence of two distinctive features of centromeric DNA. Centromeres are subject to breakage by the mechanical forces exerted by microtubules and meiotic crossing-over is suppressed. Centromeric proteins acting in trans are under selection to mitigate the costs of centromeric repeats acting in cis. Collateral costs of mitotic competition at centromeres may help to explain the high rates of aneuploidy observed in early human embryos.Capacity decay of an intercalating Li+ -storage material is mainly due to the its particle microcracks from stress-causing volume change. To extend its cycle life, its unit-cell-volume change has to be minimized as much as possible. Here, based on a γ-Li3 VO4 model material, the authors explore selective doping as a general strategy to controllably tailor its maximum unit-cell-volume change, then clarify the relationship between its crystal-structure openness and maximum unit-cell-volume change, and finally demonstrate the superiority of "zero-strain" materials within 25-60 °C (especially at 60 °C). With increasing the large-sized Ge4+ dopant, the unit-cell volume of γ-Li3+ x Gex V1- x O4 becomes larger and its crystal structure becomes looser, resulting in the decrease of its maximum unit-cell-volume change. In contrast, the doping with small-sized Si4+ shows a reverse trend. The tailoring reveals that γ-Li3.09 Ge0.09 V0.91 O4 owns the smallest maximum unit-cell-volume change of 0.016% in the research field of intercalating Li+ -storage materials. Consequently, γ-Li3.09 Ge0.09 V0.91 O4 nanowires exhibit excellent cycling stability at 25/60 °C with 94.8%/111.5% capacity-retention percentages after 1800/1500 cycles at 2 A g-1 . This material further shows large reversible capacities, proper working potentials, and high rate capability at both temperatures, fully demonstrating its great application potential in long-life lithium-ion batteries.Lithium-sulfur batteries (LSBs) with extremely-high theoretical energy density (2600 Wh kg-1 ) are deemed to be the most likely energy storage system to be commercialized. However, the polysulfides shuttling and lithium (Li) metal anode failure in LSBs limit its further commercialization. Herein, a versatile asymmetric separator and a Li-rich lithium-magnesium (Li-Mg) alloy anode are applied in LSBs. The asymmetric separator is consisted of lithiated-sulfonated porous organic polymer (SPOP-Li) and Li6.75 La3 Zr1.75 Nb0.25 O12 (LLZNO) layers toward the cathode and anode, respectively. SPOP-Li serves as a polysulfides barrier and Li-ion conductor, while the LLZNO functions as an "ion redistributor". Combining with a stable Li-Mg alloy anode, the symmetric cell achieves 5300 h of Li stripping/plating and the modified LSBs exhibit a long lifespan with an ultralow fading rate of 0.03% per cycle for over 1000 cycles at 5 C. Impressively, even under a high-sulfur-loading (6.1 mg cm-2 ), an area capacity of 4.34 mAh cm-2 after 100 cycles can still be maintained, demonstrating high potential for practical application.The binding of plasma proteins to nanomedicines is widely considered detrimental to their delivery to tumors. Here, the design of OxPt/SN38 nanoparticle containing a hydrophilic oxaliplatin (OxPt) prodrug in a coordination polymer core and a hydrophobic cholesterol-conjugated SN38 prodrug on the lipid shell for active tumor targeting is reported. OxPt/SN38 hitchhikes on low-density lipoprotein (LDL) particles, concentrates in tumors via LDL receptor-mediated endocytosis, and selectively releases SN38 and OxPt in acidic, esterase-rich, and reducing tumor microenvironments, leading to 6.0- and 4.9-times higher accumulations in tumors over free drugs. By simultaneously crosslinking DNA and inhibiting topoisomerase I, OxPt/SN38 achieved 92-98% tumor growth inhibition in five colorectal cancer tumor models and prolonged mouse survival by 58-80 days compared to free drug controls in three human colorectal cancer tumor models without causing serious side effects. The study has uncovered a novel nanomedicine strategy to co-deliver combination chemotherapies to tumors via active targeting of the LDL receptor.Face recognition has become ubiquitous for authentication or security purposes. Meanwhile, there are increasing concerns about the privacy of face images, which are sensitive biometric data and should be protected. Software-based cryptosystems are widely adopted to encrypt face images, but the security level is limited by insufficient digital secret key length or computing power. Hardware-based optical cryptosystems can generate enormously longer secret keys and enable encryption at light speed, but most reported optical methods, such as double random phase encryption, are less compatible with other systems due to system complexity. In this study, a plain yet highly efficient speckle-based optical cryptosystem is proposed and implemented. A scattering ground glass is exploited to generate physical secret keys of 17.2 gigabit length and encrypt face images via seemingly random optical speckles at light speed. Face images can then be decrypted from random speckles by a well-trained decryption neural network, such that face recognition can be realized with up to 98% accuracy. Furthermore, attack analyses are carried out to show the cryptosystem's security. Due to its high security, fast speed, and low cost, the speckle-based optical cryptosystem is suitable for practical applications and can inspire other high-security cryptosystems.The objective of this study was to examine type of services U.S. veterans seek when they experience homelessness, characteristics associated with service use, and reasons for not using services. Data from a 2021 nationally representative survey of 1004 low-income U.S. veterans were analyzed with descriptive and multivariable analyses. One-quarter of low-income U.S. veterans with experiences of homelessness reported using homeless services while they were homeless and about 27% reported using U.S. Department of Veterans Affairs (VA) healthcare or benefits while homeless. Black and Hispanic veterans were more likely to use both homeless services and VA services while homeless than veterans of other race/ethnic groups. The most common barriers to services were veterans felt they did not need help, they did not have information about services, there was stigma and shame, and transportation barriers were encountered. These findings suggest veterans use various VA and community-based homeless and healthcare services, but they do experience barriers that may be improved with better public information and care coordination to improve service uptake among homeless veterans.Noninvasive optical imaging through dynamic scattering media has numerous important biomedical applications but still remains a challenging task. While standard diffuse imaging methods measure optical absorption or fluorescent emission, it is also well-established that the temporal correlation of scattered coherent light diffuses through tissue much like optical intensity. Few works to date, however, have aimed to experimentally measure and process such temporal correlation data to demonstrate deep-tissue video reconstruction of decorrelation dynamics. In this work, a single-photon avalanche diode array camera is utilized to simultaneously monitor the temporal dynamics of speckle fluctuations at the single-photon level from 12 different phantom tissue surface locations delivered via a customized fiber bundle array. Then a deep neural network is applied to convert the acquired single-photon measurements into video of scattering dynamics beneath rapidly decorrelating tissue phantoms. The ability to reconstruct images of transient (0.
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