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Younger people's ideas regarding being able to view a residential district pharmacy for the chlamydia assessment kit: a qualitative research situated in Northern Far east Great britain.
Digital twin has the potential to be an important concept for achieving smart manufacturing. However, there remains a lot of confusion about the concept and how it can be implemented in real manufacturing systems, especially among small-to-medium-sized enterprises. This paper synthesizes the different perspectives that have been reported on the digital twin to identify the key characteristics that must be understood when developing a digital twin for a specific use case. Example applications are provided and the need for a standardized framework, such as the one under development as ISO 23247 (Digital Twin Manufacturing Framework), is motivated. This framework can enable context-dependent implementations and promote composability and reusability of digital twin components.Subjective well-being is comprised of two components affective experience and life satisfaction. Older adulthood is marked by changes and challenges that have the potential to diminish well-being. As the proportion of older adults in the population rises, it is becoming increasingly important to identify factors that may be protective against these potentially detrimental events. buy Molibresib Mindfulness and acceptance constructs have been shown to be associated with affective experience across the lifespan. However, little work has examined which facets of mindfulness drive these associations. The current study aimed to explore the associations between acceptance and mindfulness processes and positive and negative affect in older adults. Eighty-five healthy older adults completed self-report measures of mindfulness, experiential avoidance, and positive and negative affect. Results from linear regression analyses indicated that the act with awareness and nonreactivity facets of mindfulness were particularly important in their contribution to positive affect. Additionally, higher levels of experiential avoidance accounted for significant variance in negative affect. These findings help to elucidate how mindfulness and acceptance processes play a role in affective experience in older adults. Future studies should explore these facets in clinical populations to help create more targeted clinical goals.Behavioral health issues such as smoking and overweight are risk factors for a variety of adverse health outcomes, including mortality. Over the past decade, a growing number of randomized controlled trials have examined the efficacy of acceptance- and mindfulness-based interventions for smoking cessation and weight loss. The purpose of the current meta-analytic reviews was to quantitatively synthesize the existing literature comparing these interventions to controls for a) smoking cessation and b) weight loss outcomes. Searches identified 17 smoking cessation studies and 31 weight loss studies eligible for inclusion. Meta-analytic results indicated a non-significant effect favoring acceptance- and mindfulness-based interventions over controls for smoking cessation (OR = 1.13) and a small, significant effect favoring these interventions over controls for weight loss outcomes (Hedge's g = 0.30). Statistical heterogeneity and risk of bias were assessed. Subgroup and meta-regression analyses were conducted to examine moderating variables (e.g., sample and intervention characteristics). The findings indicated that acceptance- and mindfulness-based interventions were at least as efficacious as active control conditions. Given the significant health risks associated with smoking and overweight, these findings have important clinical and public health implications. Limitations (e.g., relative infancy of the literature; lack of diversity in sample demographics) and future directions (e.g., further exploration of mediators and moderators of change) are discussed.The National Coastal Property Model (NCPM) simulates flood damages resulting from sea level rise and storm surge along the contiguous U.S. coastline. The model also projects local-level investments in a set of adaptation measures under the assumption that these measures will be adopted when benefits exceed the costs over a 30-year period. However, it has been observed that individuals and communities often underinvest in adaptive measures relative to standard cost-benefit assumptions due to financial, psychological, sociopolitical, and technological factors. This study applies an updated version of the NCPM to incorporate improved cost-benefit tests and to approximate observed sub-optimal flood risk reduction behavior. The updated NCPM is tested for two multi-county sites Virginia Beach, VA and Tampa, FL. Sub-optimal adaptation approaches slow the implementation of adaptation measures throughout the 100-year simulation and they increase the amount of flood damages, especially early in the simulation. The net effect is an increase in total present value cost of $1.1 to $1.3 billion (2015 USD), representing about a 10% increase compared to optimal adaptation approaches. Future calibrations against historical data and incorporation of non-economic factors driving adaptation decisions could prove useful in better understanding the impacts of continued sub-optimal behavior.Cognitive control is central to the phenomenon of intrusive thinking in obsessive-compulsive and related disorders. The current study tested how attempts at cognitive control are impacted by self- vs. other-generated distractor thoughts. Participants (N=1913) were randomly assigned to suppress or monitor an intrusive thought and also randomly assigned to a) self-generate a distractor, b) receive a distractor, or c) receive no distractor guidance. Participants reported subsequent thought recurrences, perceived success and effort keeping the thought out of mind, and positive and negative affect during a one-minute thinking period and a one-minute monitoring period. During the first thinking period only, self-generated distractors resulted in greater perceived control (p.10). These findings suggest that the source of distractors may inform when attempts to control intrusive thinking will be helpful versus harmful.Bonding geometry engineering of metal-oxygen octahedra is a facile way of tailoring various functional properties of transition metal oxides. Several approaches, including epitaxial strain, thickness, and stoichiometry control, have been proposed to efficiently tune the rotation and tilt of the octahedra, but these approaches are inevitably accompanied by unnecessary structural modifications such as changes in thin-film lattice parameters. In this study, a method to selectively engineer the octahedral bonding geometries is proposed, while maintaining other parameters that might implicitly influence the functional properties. A concept of octahedral tilt propagation engineering is developed using atomically designed SrRuO3/SrTiO3 (SRO/STO) superlattices. In particular, the propagation of RuO6 octahedral tilt within the SRO layers having identical thicknesses is systematically controlled by varying the thickness of adjacent STO layers. This leads to a substantial modification in the electromagnetic properties of the SRO layer, significantly enhancing the magnetic moment of Ru.
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