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Open up scientific disciplines, info sharing along with unity: which advantages?
Lockdown restrictions were implemented in Italy from 10 March 2020 to contain the COVID-19 pandemic. Our study aims to evaluate air pollution changes, with focus on nitrogen dioxide (NO2), before and during the lockdown in Rome and in the surroundings. Significant NO2 declines were observed during the COVID-19 pandemic with reductions of - 50%, - 34%, and - 20% at urban traffic, urban background, and rural background stations, respectively. Tropospheric NO2 vertical column density (VCD) from the TROPOspheric Monitoring Instrument (TROPOMI) was used to evaluate the spatial-temporal variations of the NO2 before and during the lockdown for the entire area where the surface stations are located. The evaluation is concerned with the pixels including one or more air quality stations to explore the capability of the unprecedented high spatial resolution to monitor urban and rural sites from space with relation to the surface measurements. Good agreement between surface concentration and TROPOMI VCD was obtained in Rome (R = 0.64 in 2019, R = 0.77 in 2020) and in rural sites (R = 0.71 in 2019). Inversely, a slight correlation (R = 0.20) was observed in rural areas during the lockdown due to very low levels of NO2. Finally, the TROPOMI VCD showed a sharp decline in NO2, larger in urban (- 43%) than in rural sites (- 17%) as retrieved with the concurrent surface measurements averaging all the traffic and urban background (- 44%) and all the rural background stations (- 20%). These results suggest air pollution improvement in Rome gained from implementing lockdown restrictions.Petroleum exploration has continued to impact negatively the Niger Delta region of Nigeria. Oil spills from petroleum exploration contaminate both the aquatic and non- aquatic environments and destroy the ecosystem which makes people in these regions to be prone to diseases such as cancer, cardiovascular diseases, neurodegenerative disease, infertility, and sterility and also poverty. Some oxidative stress markers of the liver and muscle of fish (Clarias gariepinus) from Apata, Araromi, and Mahin rivers (located in the Niger Delta region) were compared with those of fish samples from a clean fish farm (control) in order to assess the level of pollution of the rivers. A significant increase in malondialdehyde level and myeloperoxidase (MPO) activity as well as alterations in antioxidant status (glutathione peroxidase, superoxide dismutase, reduced glutathione, and glutathione S-transferase) was observed in the organs of fish samples from Apata, Araromi, and Mahin rivers compared with the control. A significant increase in the frequency of micronucleated polychromatic erythrocytes (MnPCEs) was also observed in the fish samples from these rivers in comparison with the control. Based on results of our research, we can conclude that these rivers are polluted mainly by oil spillage and other industrial activities; therefore, the consumption of aquatic organisms from these rivers and the use of water from the rivers for domestic activities might be unsafe.The Victoria Symptom Validity Test (VSVT) is a performance validity test (PVT) with over two decades of empirical backing, although methodological limitations within the extant literature restrict its clinical and research generalizability. Chief among these constraints includes limited consensus on the most accurate index within the VSVT and the most appropriate cut-scores within each VSVT validity index. The current systematic review synthesizes existing VSVT validation studies and provides additional cross-validation in an independent sample using a known-groups design. We completed a systematic search of the literature, identifying 17 peer-reviewed studies for synthesis (7 simulation designs, 7 differential prevalence designs, and 3 known-groups designs). The independent cross-validation sample consisted of 200 mixed clinical neuropsychiatric patients referred for outpatient neuropsychological evaluation. Across all indices, Total item accuracy produced the strongest psychometric properties at an optimal cut-score of ≤ 40 (62% sensitivity/88% specificity). However, ROC curve analyses for all VSVT indices yielded statistically significant areas under the curve (AUCs; .73-81), suggestive of moderate classification accuracy. Cut-scores derived using the independent cross-validation sample converged with some previous findings supporting cut-scores of ≤ 22 for Easy item accuracy and ≤ 40 for Total item accuracy, although divergent findings were noted for Difficult item accuracy. Selleck BIX 02189 Overall, VSVT validity indicators have adequate diagnostic accuracy across populations, with the current study providing additional support for its use as a psychometrically sound PVT in clinical settings. However, caution is recommended among patients with certain verified clinical conditions (e.g., dementia) and those with pronounced working memory deficits due to concerns for increased risk of false positives.
Despite the increasing number of people with autism-spectrum disorder (ASD), intellectual disabilities (ID), and developmental disabilities (DDs), individuals with these conditions continue to have high levels of unmet physical and mental health needs. Robust training of health professionals can help bridge this gap. A systematic review was conducted to describe the features and educational outcomes of existing postgraduate medical education curricula to inform the development of future training to address the growing unmet care needs of people with intellectual and developmental disabilities (IDD) such as ASD and ID.

Four major databases were searched for peer-reviewed, English-language research focusing on post-graduate training in IDD education. Educational curricula and outcomes were summarized including Best Evidence in Medical Education (BEME) Quality of Evidence and Kirkpatrick training evaluation model.

Sixteen studies were identified with a majority published after 2000 (69%). Pediatric departments were involved in 69%, Psychiatry 19%, Medicine-Pediatrics 19%, and Family Medicine 6.3%. Analysis of Kirkpatrick outcomes showed 31% were level 1 (satisfaction or comfort); 38% level 2 (change in objective knowledge or skills); 13% level 3 (change in behavior); and none at level 4. BEME analysis showed 19% of studies were grade 1 (no clear conclusions), 31% grade 2 (ambiguous results), and half (50%) grade 3 (conclusions can probably be based on findings), with none scoring four or higher.

There is a paucity of objectively evaluated research in the area. Studies reviewed show clear promise for specialized, interdisciplinary, competency-based education which may be foundational for future curriculum development.
There is a paucity of objectively evaluated research in the area. Studies reviewed show clear promise for specialized, interdisciplinary, competency-based education which may be foundational for future curriculum development.Air pollution is a worrisome risk factor for global morbidity and mortality and plays a special role in many respiratory conditions. It contributes to around 8 million deaths/year, with outdoor exposure being responsible for more than 4.2 million deaths throughout the world, while more than 3.8 million die from situations related to indoor pollution. Pollutant agents induce several respiratory symptoms. In addition, there is a clear interference in numerous asthma outcomes, such as incidence, prevalence, hospital admission, visits to emergency departments, mortality, and asthma attacks, among others. The particulate matter group of pollutants includes coarse particles/PM10, fine particles/PM2.5, and ultrafine particles/PM0.1. The gaseous components include ground-level ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide. The timing, load, and route of allergen exposure are other items affecting allergic disease phenotypes. The complex interaction between pollutant exposures and human host factors has an implication in the development and rise of asthma as a public health problem. However, there are hiatuses in the understanding of the pathways in this disease. The routes through which pollutants induce asthma are multiple, and include the epigenetic changes that occur in the respiratory tract microbiome, oxidative stress, and immune dysregulation. In addition, the expansion of the modern Westernized lifestyle, which is characterized by intense urbanization and more time spent indoors, resulted in greater exposure to polluted air. Another point to consider is the different role of the environment according to age groups. Children growing up in economically disadvantaged neighborhoods suffer more important negative health impacts. This narrative review highlights the principal polluting agents, their sources of emission, epidemiological findings, and mechanistic evidence that links environmental exposures to asthma.In our view, the discipline, often referred to as human-animal interaction (HAI), lacks a well-defined conceptual framework. It is too narrow both with respect to the animal species investigated and the nature of human-animal interactions studied. So instead, we introduce the term human-companion animal partnership (HCAP) that is not only a better descriptor for most research efforts within HAI but also helps to direct research efforts on an ethological basis. In our approach, 'companion' is a function and not a feature of some species. This means that many species had and could have a potential to form mixed social groups with humans if they evolve some capacity of social competence. This view may initiate new comparative research involving a range of species to find out how complex social engagement could be maintained in such hetero-specific social groups based on evolutionary heritage, recent selection and individual experience (socialisation). Our approach emphasises the role of human caring behaviour and social competence in the emergence of a partnership with several species, and thus could also help in setting expectations for welfare and aid in designing artificial companions for specific purposes.I argue that an enactivist framework has more explanatory power than traditional philosophical theories of cognition when it comes to understanding the mechanisms underlying human-animal relationships. In both intraspecies and interspecies exchanges, what we often find are novel forms of cognition emerging from such transactions, but these "co-cognitive" processes cannot be understood apart from the interaction itself. I focus on a specific form of human-animal interaction-play, as it occurs between humans and domestic dogs-and argue that the best theory suited to the task of explaining how these two species create unique thought processes is a "sympoietic enactivism." Rather than the more common "autopoietic" arguments defended by many enactivists, I argue that what is more accurately occurring during bouts of human-dog play is sympoietic, or "collectively producing." Drawing on several different disciplines that converge on similar conclusions about creativity and collaboration, I show that human-dog play is a quintessential case of cognition that cannot be readily understood by appealing to the inner workings of either individual among the dyad. Thinking, on this view, is a form of play, and in playful interaction what gets created are wholly intersubjective modes of thought.
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