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Multiple linear regressions revealed higher dispositional mindfulness to interact with aspects of positive schizotypy associated with heightened creative experience of power/pleasure (b = 0.06, p = .03), clarity/preparation (b = 0.03, p = .004), and differing levels of anxiety associated with creative engagement (b = -0.06, p = .003; b = 0.03, p = .047). Higher dispositional mindfulness was also associated with lower suspiciousness (rs = -0.33, p less then .001). The study highlights the importance of considering the role of suspiciousness/paranoia when investigating the relationship between positive schizotypy and creativity. The findings provide support for the application of mindfulness-based interventions for mitigating psychosis-risk associated with suspiciousness, whilst supporting the otherwise favourable association of positive schizotypy with creativity.Self-stigma in mental illness is linked to negative clinical and functional outcomes, but little is known about its correlates specifically in psychotic disorders. Here we investigated the role of clinical symptoms, cognition, and vocational status as correlates of self-stigma in 98 individuals with psychotic disorders (36 Black American, 32 White Hispanic, 11 White Non-Hispanic, 11 Asian American). A principal component analysis of the Internalized Stigma of Mental Illness scale yielded three components Experiential Stigma, Stereotype Endorsement, and Stigma Resistance. Higher Experiential Stigma was associated with greater severity of affective symptoms and lower vocational status. Higher Stigma Resistance was associated with higher social and non-social cognition, and higher vocational status. Stereotype Endorsement did not significantly correlate with any predictor variable. Linear regression models showed that 13% of the variance in Experiential Stigma was explained by affective symptoms and vocational status, and 20% of the variance in Stigma Resistance was explained by non-social cognition and vocational status. These findings provide new information about the correlates of self-stigma in an ethnically and racially diverse psychotic disorder sample. Such information may lead to a better understanding of self-stigma mechanisms in this population.
Beyond the effects of the coronavirus pandemic on the public's health, the length of lockdown and its possible psychological impacts on populations is heavily debated. However, the consequences of lockdown on psychotic symptoms have been poorly investigated.

An online survey was run from April 13 to May 11, 2020; a total of 728 French subjects from the general population were included in the study. We assessed the perceived impact of the COVID-19 outbreak, length of isolation, diagnosis/symptoms/hospitalisation related to the COVID-19 (oneself and family). Paranoid ideations and hallucination-like experiences were assessed via the Paranoia Scale and the Cardiff Anomalous Perceptions Scale, respectively. Self-reported measures of negative affect, loneliness, sleep difficulties, jumping to conclusion bias, repetitive thoughts, among others, were also included.

Final regression model for paranoia indicated that socio-demographic variables (age, sex and education), loneliness, cognitive bias, anxiety, experdevelopment of psychotic symptoms in the context of a pandemic and lockdown measures.Scorpions are among the most popular research objects within Arachnida and there is an impressive body of knowledge about their biology, distribution, morphology, etc. Although the poison sting has gained a lot of attention due to its potential lethal effects to humans, hitherto, there has been no comparative morphological study on the metasoma, the body part that delivers the poisonous injection. The metasoma always consists of five body segments terminated by a poison sting, but it presents significant morphological variations, both between sexes and between species. Its form ranges from long and thin to short and rather reduced to thick and dominant. In this study, we investigated species representing major scorpion clades and most of the known morphological disparity. Using high-resolution micro-computer-tomography and 3D-reconstruction, we present the first 3D visualizations of metasomal exo-skeletal elements in combination with their musculature. Despite of morphological varying metasomal forms, in all investigated species, a repeating pattern of muscles was found four pairs of muscles in metasomal segment one to four and two pairs of muscles in metasomal segment five. However, the metasomal muscles are characterized by an antero-posterior change in their shapes and sizes and interspecific variation was also found in the extrinsic metasomal musculature, i.e. buy L-Glutamic acid monosodium the muscles that link metasoma to mesosoma.Contact tracing via smartphone applications is expected to be of major importance for maintaining control of the COVID-19 pandemic. However, viable deployment demands a minimal quarantine burden on the general public. That is, consideration must be given to unnecessary quarantining imposed by a contact tracing policy. Previous studies have modeled the role of contact tracing, but have not addressed how to balance these two competing needs. We propose a modeling framework that captures contact heterogeneity. This allows contact prioritization contacts are only notified if they were acutely exposed to individuals who eventually tested positive. The framework thus allows us to address the delicate balance of preventing disease spread while minimizing the social and economic burdens of quarantine. This optimal contact tracing strategy is studied as a function of limitations in testing resources, partial technology adoption, and other intervention methods such as social distancing and lockdown measures. The framework is globally applicable, as the distribution describing contact heterogeneity is directly adaptable to any digital tracing implementation.Anterior cruciate ligament (ACL) rupture alters knee kinematics and contributes to premature development of osteoarthritis. However, there is limited data regarding the in vivo biomechanical response of tibiofemoral cartilage to activities of daily living (ADLs) in ACL-deficient knees. In this study, eight otherwise healthy participants with chronic unilateral ACL deficiency completed a stress test to assess the effect of 20 min of level treadmill walking at a speed of 2.5 mph on tibiofemoral cartilage in their ACL-deficient and contralateral ACL-intact knees. Three-dimensional surface models developed from pre- and post-activity magnetic resonance (MR) images of the injured and uninjured knees were used to determine compressive strain across multiple regions of tibiofemoral cartilage (medial and lateral tibial plateaus, medial and lateral femoral condyles, medial aspect of femoral condyle adjacent to intercondylar notch of the femur). In the ACL-deficient knees, we observed significantly increased cartilage strain in the region of the medial femoral condyle adjacent to the intercondylar notch (6% in deficient vs.
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