Notes

"Ninja Technique" for Percutaneous Finishing of Partial-Thickness, Articular-Sided Rotator Cuff Holes.
There were no statistical differences in the prevalence of NCCLs with or without erosive etiological factors except for the 60-69years group.

NCCL distribution increased with age, and erosive risk factors caused by change in dietary habits might affect the incidence of NCCLs for elders.

UMIN000041982.
UMIN000041982.
To analyze the stress distribution and subsequent fracture resistance of human maxillary premolars with mesial-occlusal-distal (MOD) defects restored with different minimally invasive restorations.

Seventy non-carious human maxillary premolars were selected and divided into seven groups (n = 10). Ten teeth without further preparation served as control. The remaining teeth were endodontically treated and received three restorative patterns inlays without cusp coverage (I), onlays with palatal coverage (O), overlays with both buccal and palatal coverage (Ov). Lithium disilicate glass ceramics (EM) and machinable composite resin (LU) were used for restoration. Specimens were tested under cycling loading with tongue direction of 45° for 1.2 × 10
cycles at a 50-N load and 2.0-Hz frequency. The survival time and two fracture mode classifications were assessed. Three-dimensional models of each group were designed. The magnitude and pattern of stresses were analyzed under the same condition of the in vitro test using finite element stress analysis.

Although the overlay model pattern produced more favorable stress distribution, three restorative patterns restored with the same material had no difference in survival curves (P > 0.05). Only the survival curve of the EM-Ov group had no statistical difference with that of the control group (P > 0.05). EM groups presented mainly interface adhesive failure, while LU groups were mainly material cohesive failure.

For the endodontically treated maxillary premolars with MOD defect, the lithium disilicate glass ceramic overlay pattern can reach the best restorative effect.

Comparing with restorative pattern, restorative material had a greater influence on the minimally invasive restoration of posterior teeth.
Comparing with restorative pattern, restorative material had a greater influence on the minimally invasive restoration of posterior teeth.
Growing consideration in quality of life (QoL) has changed the therapeutic strategy in patients suffering from diverticular disease. Patients' well-being plays a crucial role in the decision-making process. However, there is a paucity of studies investigating patients' or surgery-related factors influencing the postoperative gastrointestinal function. The aim of this study was to investigate in a predictive model patients or surgical variables that allow better estimation of the postoperative gastrointestinal QoL.

This observational study retrospectively analyzed patients undergoing elective laparoscopic sigmoidectomy for diverticulitis between 2004 and 2017. The one-time postoperative QoL was assessed with the gastrointestinal quality of life index (GIQLI) in 2019. A linear regression model with stepwise selection has been applied to all patients and surgery-related variables.

Two hundred seventy-two patients with a mean age of 62.30 ± 9.74 years showed a mean GIQLI of 116.39±18.25 at a mean follow-up time of 90.4±33.65 months. Women (n=168) reported a lower GIQLI compared to male (n=104; 112.85±18.79 vs 122.11±15.81, p<0.001). Patients with pre-operative cardiovascular disease (n=17) had a worse GIQLI (106.65 ±22.58 vs 117.08±17.66, p=0.010). Finally, patients operated less than 5 years ago (n=63) showed a worse GIQLI compared to patients operated more than 5 years ago (n=209; 111.98±19.65 vs 117.71±17.63, p=0.014).

Female gender and the presence of pre-operative cardiovascular disease are predictive for a decreased postoperative gastrointestinal QoL. Furthermore, patients' estimation of gastrointestinal functioning seems to improve up to 5 years after surgery.
Female gender and the presence of pre-operative cardiovascular disease are predictive for a decreased postoperative gastrointestinal QoL. Furthermore, patients' estimation of gastrointestinal functioning seems to improve up to 5 years after surgery.
The prognostic significance of the surgical margin status remains controversial for patients who undergo hepatectomy for colorectal liver metastases. This study evaluated the influence of R1 resection on recurrence patterns and prognosis in these patients.

Between January 2001 and December 2016, 232 consecutive Japanese patients underwent initial hepatic resection for colorectal liver metastases. Their medical records were reviewed to evaluate recurrence and survival outcomes.

Relative to patients with R0 resection, patients with R1 resection had significantly poorer recurrence-free survival (RFS) and overall survival (OS). However, after propensity score matching, there were no significant differences in RFS and OS associated with the margin status. Nevertheless, R1 resection was associated with a significantly higher incidence of intrahepatic recurrence and early recurrence, while R0 resection was associated with a significantly higher re-resection rate for hepatic recurrence. Only eight of 55 patients with R1 resection developed recurrence at the R1 resection margin, whereas 36 patients developed recurrence at other sites/organs.

Among patients with similar characteristics, R1 resection does not affect long-term outcomes. This suggests that R1 resection itself is not a cause of a poor prognosis, but rather a potent indicator of aggressive tumor biology.
Among patients with similar characteristics, R1 resection does not affect long-term outcomes. This suggests that R1 resection itself is not a cause of a poor prognosis, but rather a potent indicator of aggressive tumor biology.Plant growth-promoting bacteria (PGPB) are bacteria that have mechanisms that facilitate plant growth in stress conditions such as drought. The objective of this study was to characterize bacterial strains isolated from bromeliads roots in ironstone outcrops (Urucum Residual Plateau, Mato Grosso do Sul, Brazil) for plant growth-promoting under drought conditions. Firstly, we screened isolates with the presence of 1-aminocyclopropane-1-carboxylate (ACC) deaminase activity. ACBI1 price Then, all isolates were tested for tolerance to drought, exopolysaccharides (EPS) production, indole-3-acetic acid (IAA)-producing abilities, phosphate and zinc solubilization, production of catalase and hydrolytic enzymes (amylase, cellulase, and protease). Germination assay and a pot experiment with maize plants submitted to well-watered and drought conditions were performed with the strains most promising (VBN11 and VBE23). Briefly, Bacillus cereus VBE23 showed in vitro higher ACC deaminase activity (3.83 and 2.52 µmol α-KB mg-1 h-1 in non-drought and drought conditions, respectively), tolerance to drought, EPS production and other mechanisms of plant growth promotion solubilization of phosphate and zinc, ammonia production, catalase activity and production of hydrolytic enzymes (amylase, cellulase, and protease). Inoculation of strain VBE23 in maize seeds submitted to drought conditions showed higher germination concerning uninoculated seeds and inoculated with VBN11. Also, the results indicated that the isolate VBE23 provided higher values of fresh and dry biomass compared to the control of uninoculated treatment and inoculated with VBN11 under drought conditions. This is the first report on the PGPB from ironstone outcrops of Urucum Residual Plateau, Mato Grosso do Sul, Brazil. Thus, this bacterial isolate could be used as a strategy for the facilitation of plant growth in drought environments.A Gram-positive, catalase-negative, coccus-shaped, chain-forming organism isolated from the oropharynx of a healthy child in Shenyang, China, was subjected to phenotypic and molecular taxonomic analyses. 16S rRNA sequence analysis indicated that this bacterium represents a new member of the genus Streptococcus and is closely related to Streptococcus oralis subsp. dentisani DSM 27088. According to DNA-DNA hybridization analysis, strain D19T was less than 70% similar to other strains with close genetic relationships. Fatty acid analysis, physiological, and biochemical tests showed that strain D19T was different from the published Streptococcus species. The genome of strain D19T is 2,023,003 bp long with a GC content of 39.9 mol%. It contains 1889 protein-coding genes and 50 RNA genes. These results show that Streptococcus shenyangsis sp. nov. strain D19T is a new species.
There has been a paucity of literature evaluating the role of mediolateral femoral component position (FCP) in medial unicompartmental arthroplasty (UKA). Hence, the aim of this study is to evaluate whether the mediolateral FCP in UKA will affect the 10-year clinical outcomes and quality of life of patients who underwent medial UKA.

Data of 262 patients who underwent medial UKA were analyzed. All patients were assessed at 6 months, 2 years and 10 years using the Knee Society Function Score, Knee Society Knee Score, Oxford Knee Score, Short-Form 36 Physical/Mental Component Scores and postoperative satisfaction. The mediolateral FCP on postoperative radiographs was measured by independent assessors using the Picture Archiving and Communication Systems. 144 patients were distributed into group C (center), 98 into group M (medial) and 20 into group L (lateral) according to FCP, and one-way ANOVA was used to compare the functional outcomes of the three groups.

No statistical differences were found between the three groups in terms of 10-year clinical outcomes, quality of life, satisfaction rates and revision rates.

Differences in mediolateral FCP did not result in significant difference in 10-year postoperative clinical outcomes for patients who underwent fixed-bearing medial UKAs.

Retrospective study, Level III.
Retrospective study, Level III.
Exercise oscillatory ventilation (EOV) is a form of periodic breathing that is associated with a poor prognosis in heart failure patients, but little is known about EOV in other populations. We sought to provide insights into the phenomenon of EOV after it was observed in young healthy subjects, including athletes, after the administration of dual autonomic blockade (DAB).

From 29 participants who completed cardiopulmonary exercise testing (CPET) with and without DAB (0.04mg/kg atropine and 0.2mg/kg metoprolol), 5 subjects developed EOV (age = 29 ± 5years; 3/5 were athletes) according to American Heart Association criteria. For each case, we identified 2 non-EOV healthy controls (age = 34.2 ± 8.3; 7/10 were athletes) that were subsequently age- and sex-matched.

No participants had EOV during exercise without DAB. The 5 participants (4 male, 1 female) who demonstrated EOV with DAB had lower mean tidal volume (1.7 ± 0.5 L/min vs. 1.8 ± 0.5 L/min; p = 0.04) compared to participants in the non-EOV group and a decrease in peak tidal volume (2.9 ± 0.6 L/min to 2.2 ± 0.7 L/min; p = 0.004) with DAB. There were few other differences in CPET measures between EOV and non-EOV participants, although the PETCO2 tended to be higher in the EOV group (p = 0.07).

EOV can be elucidated in young healthy subjects, including athletes, during cardiopulmonary exercise testing, suggesting that it may not be an ominous sign in all populations.
EOV can be elucidated in young healthy subjects, including athletes, during cardiopulmonary exercise testing, suggesting that it may not be an ominous sign in all populations.
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