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85 to infer the signal-to-noise ratio of recordings with varying quality levels. The method is validated on a large dataset of lung auscultation recorded in various clinical settings with controlled varying degrees of noise interference. The proposed metric is also validated against opinions of expert physicians in a blind listening test to further corroborate the efficacy of this method for quality assessment.Respiratory condition has received a great amount of attention nowadays since respiratory diseases recently become the globally leading causes of death. Traditionally, stethoscope is applied in early diagnosis but it requires clinician with extensive training experience to provide accurate diagnosis. Accordingly, a subjective and fast diagnosing solution of respiratory diseases is highly demanded. Adventitious respiratory sounds (ARSs), such as crackle, are mainly concerned during diagnosis since they are indication of various respiratory diseases. Therefore, the characteristics of crackle are informative and valuable regarding to develop a computerised approach for pathology-based diagnosis. In this work, we propose a framework combining random forest classifier and Empirical Mode Decomposition (EMD) method focusing on a multi-classification task of identifying subjects in 6 respiratory conditions (healthy, bronchiectasis, bronchiolitis, COPD, pneumonia and URTI). Specifically, 14 combinations of respiratory sound segments were compared and we found segmentation plays an important role in classifying different respiratory conditions. The classifier with best performance (accuracy = 0.88, precision = 0.91, recall = 0.87, specificity = 0.91, F1-score = 0.81) was trained with features extracted from the combination of early inspiratory phase and entire inspiratory phase. To our best knowledge, we are the first to address the challenging multi-classification problem.Tracheal sounds represent information about the upper airway and respiratory airflow, however, they can be contaminated by the snoring sounds. The sound of snoring has spectral content in a wide range that overlaps with that of breathing sounds during sleep. For assessing respiratory airflow using tracheal breathing sound, it is essential to remove the effect of snoring. In this paper, an automatic and unsupervised wavelet-based snoring removal algorithm is presented. Simultaneously with full-night polysomnography, the tracheal sound signals of 9 subjects with different levels of airway obstruction were recorded by a microphone placed over the trachea during sleep. The segments of tracheal sounds that were contaminated by snoring were manually identified through listening to the recordings. The selected segments were automatically categorized based on including discrete or continuous snoring pattern. Segments with discrete snoring were analyzed by an iterative wave-based filtering optimized to separate large spectral components related to snoring from smaller ones corresponded to breathing. Those with continuous snoring were first segmented into shorter segments. Then, each short segments were similarly analyzed along with a segment of normal breathing extracted from the recordings during wakefulness. The algorithm was evaluated by visual inspection of the denoised sound energy and comparison of the spectral densities before and after removing snores, where the overall rate of detectability of snoring was less than 2%.Clinical Relevance- The algorithm provides a way of separating snoring pattern from the tracheal breathing sounds. Therefore, each of them can be analyzed separately to assess respiratory airflow and the pathophysiology of the upper airway during sleep.We propose a robust and efficient lung sound classification system using a snapshot ensemble of convolutional neural networks (CNNs). A robust CNN architecture is used to extract high-level features from log mel spectrograms. The CNN architecture is trained on a cosine cycle learning rate schedule. Capturing the best model of each training cycle allows to obtain multiple models settled on various local optima from cycle to cycle at the cost of training a single mode. Therefore, the snapshot ensemble boosts performance of the proposed system while keeping the drawback of expensive training of ensembles moderate. To deal with the class-imbalance of the dataset, temporal stretching and vocal tract length perturbation (VTLP) for data augmentation and the focal loss objective are used. https://www.selleckchem.com/products/10-dab-10-deacetylbaccatin.html Empirically, our system outperforms state-of-the-art systems for the prediction task of four classes (normal, crackles, wheezes, and both crackles and wheezes) and two classes (normal and abnormal (i.e. crackles, wheezes, and both crackles and wheezes)) and achieves 78.4% and 83.7% ICBHI specific micro-averaged accuracy, respectively. The average accuracy is repeated on ten random splittings of 80% training and 20% testing data using the ICBHI 2017 dataset of respiratory cycles.This paper focuses on the use of an attention-based encoder-decoder model for the task of breathing sound segmentation and detection. This study aims to accurately segment the inspiration and expiration of patients with pulmonary diseases using the proposed model. Spectrograms of the lung sound signals and labels for every time segment were used to train the model. The model would first encode the spectrogram and then detect inspiratory or expiratory sounds using the encoded image on an attention-based decoder. Physicians would be able to make a more precise diagnosis based on the more interpretable outputs with the assistance of the attention mechanism.The respiratory sounds used for training and testing were recorded from 22 participants using digital stethoscopes or anti-noising microphone sets. Experimental results showed a high 92.006% accuracy when applied 0.5 second time segments and ResNet101 as encoder. Consistent performance of the proposed method can be observed from ten-fold cross-validation experiments.In addition to the global parameter- and time-series-based approaches, physiological analyses should constitute a local temporal one, particularly when analyzing data within protocol segments. Hence, we introduce the R package implementing the estimation of temporal orders with a causal vector (CV). It may use linear modeling or time series distance. The algorithm was tested on cardiorespiratory data comprising tidal volume and tachogram curves, obtained from elite athletes (supine and standing, in static conditions) and a control group (different rates and depths of breathing, while supine). We checked the relation between CV and body position or breathing style. The rate of breathing had a greater impact on the CV than does the depth. The tachogram curve preceded the tidal volume relatively more when breathing was slower.
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