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Dosiomics-based forecast regarding radiation-induced thyroid problems inside nasopharyngeal carcinoma sufferers.
Spinal intradural tumors can be classified as intradural extramedullary or intramedullary tumors. Spinal meningiomas are among the most frequent intradural, extramedullary tumors (IDEMs), representing 12 % of all meningiomas and 25-45 % of all intradural spinal tumors.

To evaluate postoperative outcome, defined by mortality, tumor recurrence and modified Rankin Scale in patients with spinal meningiomas. Furthermore, to identify factors related to these outcome measures and define possible prognosticators.

A large single center retrospective analysis of 166 consecutive spinal meningioma patients during a 29-year period (1989-2018).

Female to male ratio was 5.15 to 1. Of all 166 resected tumors, 159 were WHO grade I and seven were WHO grade II. Histopathologically, the psammomatous type was most common (42.8 %). The thoracic region was the most frequent location (71.1 %), followed by cervical and lumbar locations. A complete resection (Simpson I-III) was achieved in 88.7 %. In 12 cases (7.2 %) recurrency and mortality is relatively low. Longer follow-up periods are recommended, since recurrences can occur after 10-15 years.
The primary treatment of spinal meningiomas remains surgery. Complete resection of spinal meningiomas is achieved in most of the cases, however preserving and improving neurological status has priority over complete tumor resection. Morbidity and mortality is relatively low. Longer follow-up periods are recommended, since recurrences can occur after 10-15 years.We report the low-temperature studies of liquid CH3CN by Raman spectral measurements at ambient pressure with decreasing the temperature from 20 to -196 °C. Detailed internal modes especially the lattice modes analysis revealed that the structural phase transitions of acetonitrile from liquid to solid phase β and solid phase β to solid phase α were occurring at -50 and -60 °C, respectively. Further, the Fermi resonance parameters between the fundamental ν2 and combination (ν3 + ν4) of CH3CN at different temperatures were calculated based on the Bertran's equations. It is found that the Fermi resonance parameters as a function of temperature become discontinued at -50 and -60 °C, which coincides with discontinuities observed in the Raman shifts of CH3CN at -50 and -60 °C. The results suggest that the Fermi resonance parameters could be used as an indicator to assess the structural phase transition for CH3CN under low temperature.The effect of the laser frequency tuning rate on a weak optical absorption line profile ~(10-5-10-7) cm-1 under conditions when the molecules were in a high-quality optical resonator was studied. The authors used a diode laser and an analytical cavity with two pairs of mirrors with reflectivity of 99% and 99.98% in the ~1.4 μm region. Water vapor at reduced pressure (0.03-1) Torr served as an absorbing medium. A high spectral resolution was obtained by directing laser radiation into the cavity with a small offset relative to its axis (off-axis ICOS). The frequency tuning rate was varied within (102-103) cm-1 s-1. With the increase of the rate, a shift and asymmetry of the Doppler absorption profile were observed. When the tuning direction was changed and the rate was kept the same, the effect preserved in time and mirrored symmetrically on the frequency scale. The measurements were consistent with calculations that took into account the finite lifetime of photons in the cavity and the real ratio of the effective optical path to the coherence length of the laser radiation. Limitations on the frequency tuning rate were discussed using quantitative absorption spectroscopy methods for measuring molecule concentrations.A simple hydroxyl-substituted triphenyl-imidazole based receptor (HTPI) which selectively detects Cu2+ ion by colorimetric and fluorimetric methods was developed. HTPI detects the Cu2+ ions with the absorption enhancement and fluorescence quenching by the possible ligand to metal charge transfer (LMCT) and the chelation-enhanced quenching (CHEQ) approaches, respectively. HTPI showed high selectivity and sensitivity for Cu2+ ions detection over other interfering and competing metal ions. Interestingly, HTPI detects Cu2+ ion (LOD) at nanomolar concentrations (19 × 10-9 M (UV-vis) & 27 × 10-9 M (fluorescence), respectively), which is lower than the permissible level of Cu2+ ion reported by World Health Organization (WHO). Furthermore, HTPI was applied to the molecular logic gate function by using chemical inputs, and Cu2+ ion was potentially removed (95%) via Capacitive Deionization technique.
Laparoscopic reoperation of postoperatively diagnosed gallbladder cancer is a technically challenging procedure due to inflammatory adhesion or fibrosis around the hepatoduodenal ligament and gallbladder bed [1,2]. Here we describe a technique for laparoscopic bile duct resection with lymph node dissection in a patient with cystic duct cancer diagnosed after laparoscopic cholecystectomy.

A 73-year-old woman presented with postoperatively diagnosed gallbladder cancer. She underwent laparoscopic cholecystectomy to treat symptomatic gallbladder stones at another hospital, 2 months earlier. Postoperative pathology revealed a 0.9×0.7 cm, T2 lesion of adenosquamous carcinoma located at the cystic duct. The cystic duct margin showed high-grade dysplasia. We planned to perform laparoscopic bile duct resection with lymph node dissection. After adhesiolysis to expose the hepatoduodenal ligament, the lymph nodes were dissected around the retropancreatic area, hepatoduodenal ligament, and common hepatic artery in an en bloc fashion. Combined segmental resection of the bile duct, including the fibrotic scar around the cystic duct stump, was completed with negative resection margins. Retrocolic choledochojejunostomy and side-to-side jejunojejunostomy were then performed intracorporeally.

The operation time was 195 minutes and the estimated intraoperative blood loss was minimal. SU5402 The postoperative pathologic report revealed no residual tumor tissue and negative resection margins. Lymph node metastasis was found in one of eight retrieved lymph nodes. The patient was discharged on postoperative day 4 with no postoperative complications.

Laparoscopic radical surgery involving bile duct resection and lymph node dissection can be safely performed in patients with postoperatively diagnosed gallbladder cancer.
Laparoscopic radical surgery involving bile duct resection and lymph node dissection can be safely performed in patients with postoperatively diagnosed gallbladder cancer.
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