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The actual direct fees involving coronary CT angiography when compared with contrast-enhanced thoracic CT: Time-driven activity-based pricing.
The aim Revealing of clinical-pathogenetic peculiarities in manifestations of uncontrolled As+MS.

Materials and methods Sixty-five cases, divided into 2 groups Group I - severe As (n=20), Group 2 - severe As+MS (n=45). The general clinical examination included fasting blood glucose, insulin level, HOMA-IR index, body mass index (BMI), spirometry, levels of ММР-9, МСР-1, IL-8 and IL-12.

Results In Group I, 20 patients (100%) had obstructive respiratory dysfunction. Group II had 13 cases (28.88%) with the restrictive, 15 (33.33%) with the obstructive and 17 (37.77%) with the mixed types. BMI revealed Group I had the normal mass (BMI averaged 24.62 [22.76; 25.71]; Group II had 21 overweighed cases (46.66%) and 24 (53.33%) with grade 1 obesity, averaging 29.70 [28.35; 31.23]. Correlation analysis in Group II showed significant correlations between age and WHR (r=0.52, p<0.001) (increase of abdominal fat depots during life), FEV1 and BMI (r=-0.63, р<0.001) (obesity affects pulmonary function). IL-8 and IL-12 levels in Group II were increased, respectively, by 27.86 and 13.18 times versus Group I. A relationship was found between MCP-1 and MMP-9 (r=0.77, р<0.05), Group II revealed direct correlation between MCP-1 and total FEV1 (r=0.53, р<0.05).

Conclusions Overweight and obesity in As+MS deteriorate respiratory function versus the same indices in isolated As. Relationships between proinflammatory cytokines and MMP-9 and MCP-1 prove pathogenetic peculiarities of systemic inflammation and metabolic homeostasis. As and MS can cause their coexistence, facilitating development of mutual aggravation.
Conclusions Overweight and obesity in As+MS deteriorate respiratory function versus the same indices in isolated As. Relationships between proinflammatory cytokines and MMP-9 and MCP-1 prove pathogenetic peculiarities of systemic inflammation and metabolic homeostasis. As and MS can cause their coexistence, facilitating development of mutual aggravation.
The aim The purpose of the research was to increase the efficiency of treatment at patients with dentition defects and functional disorders of the temporomandibular joint.

Materials and methods We examined 140 patients aged from 25 to 65 years with functional disorders of the temporomandibular joint, analysed there diagnostic models in the articulator and 3D scanner, used radiographic methods of examination and condylography.

Results The results of the conducted studies showed that in the 1st group, the biomechanical parameters of temporomandibular joint movements before treatment were significantly lower 6,4 ± 0,2 mm and 6,8 ± 0,2 mm for right and left temporomandibular joint during protrusion movements; 7,8 ± 0,1 mm and 7,9 ± 0,2 mm during vertical movements; 6,7 ± 0,1 mm and 6,5 ± 0,2 mm during transversal movements. After 12 month of complex and prosthetic treatment with a help of non-removable dentures the magnitude of movements remains at the achieved level at all excursions. PCO371 As a result, proposed by us comprehensive treatment of functional disorders of the temporomandibular joint is carried out in stages. The proposed design of an individual tire makes it possible to gradually increase the bite height and perfectly forms the occlusal ratio. After 6 and 12 months of the proposed treatment, we have found that the indicators of vertical and protrusion movements of articular heads at patients of 2nd group were significantly better than before treatment.

Conclusions The proposed design of an individual tire makes it possible to gradually increase the bite height and perfectly forms the occlusal ratio.
Conclusions The proposed design of an individual tire makes it possible to gradually increase the bite height and perfectly forms the occlusal ratio.
The aim Make complex study of bone density in patients with primary osteoarthritis and exocrine pancreatic insufficiency and patients with primary osteoarthritis without exocrine pancreatic insufficiency.

Materials and methods There were examined 140 patients with primary osteoarthritis without exocrine pancreatic insufficiency and combination osteoarthritis and exocrine pancreatic insufficiency. Diagnosis of osteoarthritis was based on diagnostic X-Ray criteria - according to J.H. Kellgren and J.S. Lawrence. The level of exocrine pancreatic insufficiency was based on result of Elisa test. State of mineral bone density was examined by using dual-photon densitometry.

Results It was established that there was a progressive, statistical, significant increase of mineral density of bone tissue in the 1-st group patients with osteoarthritis. Patients in the 2-nd group, with osteoarthritis in the comorbidity with exocrine pancreatic insufficiency, the densitogram rates were statistically significantly lower than in patients in the 1-st group.

Conclusions The changes of bone tissue can be explained by the formation of trophological insufficiency as a result of exocrine pancreatic insufficiency. One of the symptoms of trophic failure is bone and mineral changes, in particular, the decrease of bone density.
Conclusions The changes of bone tissue can be explained by the formation of trophological insufficiency as a result of exocrine pancreatic insufficiency. One of the symptoms of trophic failure is bone and mineral changes, in particular, the decrease of bone density.
The aim Was a comprehensive study of the changes in features like structural and functional parameters of brain tissue, cytokine profile and β-adrenoceptor in the acute period of ischemic stroke (IS) to optimise diagnosis and treatment. The study was conducted at the Department of Neurosurgery and Neurology at the Medical Institute of Sumy State University.

Materials and methods Measurements of complex dielectric constant (CDC) were performed by EHF dielectrometry. Determination of plasma levels of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) was performed by solid-phase enzyme-linked immunosorbent assay. The work was based on the materials of a comprehensive examination of 350 patients with the first in the life of IS on the 1st, 10th and 21st day of the disease.

Results Cerebral hypoxia leads to a significant increase in the CDC of erythrocyte membranes (about 15 %), which may lead to a rise in the volume fraction of water in cell suspensions due to damage of their membrane-receptor complex (MRC).
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