Notes

Gene signatures as well as prospective therapeutic objectives associated with Midsection Eastern respiratory malady coronavirus (MERS-CoV)-infected human lungs adenocarcinoma epithelial cells.
Tanshinol relieves ulcerative colitis by promoting the actual term of VLDLR.
Diminished hyaluronan cross-linking brings about breast cancer malignancy inside a CAF-dependent manner.


Presence of a companion during prenatal care and delivery was associated with better quality of care.
Presence of a companion during prenatal care and delivery was associated with better quality of care.
To analyze temporal trend and spatial distribution of syphilis in pregnancy and congenital syphilis in Goiás State, Brazil, between 2007 and 2017.

This was an ecological time series and spatial distribution study with data obtained from the Notifiable Health Conditions Information System. Prais-Winsten Regression was used to analyze indicator trends by health macro-region. Descriptive spatial analysis was performed to verify case distribution in three different years in the period.

Between 2007 and 2017, 7,679 cases of syphilis in pregnancy and 1,554 congenital syphilis cases were reported. A rising trend was found in the rates of syphilis in pregnancy (annual percent change [APC] = 18.0 - 95% confidence interval [95%CI] 15.3;20.8) as well as in congenital syphilis rates (APC=16.8 - 95%CI 20.1;33.8); and a 326% increase in the number of municipalities with a congenital syphilis incidence rate >0.5/1,000 live births.

Growth in syphilis in pregnancy and congenital syphilis detection rates was identified, as was growth in the number of municipalities reporting cases.
Growth in syphilis in pregnancy and congenital syphilis detection rates was identified, as was growth in the number of municipalities reporting cases.
to evaluate the lingual frenulum and breastfeeding in infants from a maternal-perinatal referral center, as well as to monitor infants with ankyloglossia up to six months of age.

a cohort study conducted at the Instituto Nacional Materno Perinatal - Maternidad de Lima in Lima, Peru. The consecutive intentional sample consisted of 304 newborns and their respective mothers, evaluated during December 2017 and January 2018, which were the baseline of the study. A clinical evaluation of the lingual frenulum adapted and the Clinical Evaluation of Breastfeeding Efficacy (CEBE) scale, was performed.

of the 304 newborns, 15 (4.9%) were considered with altered frenulum, and only 4 (26.7%) presented a low score in CEBE. The mean of the CEBE score was 9.3. Selleckchem Tanespimycin Selleckchem Tanespimycin (DP=1.35, Min=3, Max=10). Of the follow-up infants, only 2 (13.3%) persisted with breastfeeding difficulties for which frenotomy was indicated.

This study demonstrates the low prevalence of ankyloglossia in infants, as it does not indicate a trend of difficulty or negative interference in breastfeeding.
This study demonstrates the low prevalence of ankyloglossia in infants, as it does not indicate a trend of difficulty or negative interference in breastfeeding.
The speech therapy practice in mental health is questioned by the challenge of producing shared care strategies to, above all, expand the conditions and the communicational repertoire, the discursive and social circulation of people with mental suffering. link= Selleckchem Tanespimycin Objective of this study was to identify the perception of clinical listening in professionals of Child and Adolescent Psychosocial Care Center (CAPSij), specifying the role of speech therapy in the care and listening of patientes.

This is a participatory and dialogical research. A discussion group was used to collect data.

were grouped in the following categories listening conception; listening and working process; listening effects; speech therapy and clinical listening. These professionals think of clinical listening as a central device for mental health care. The clinical listening favors reflection on the bio psychic dynamics of healthcare. It was observed contributions of speech therapy in intra and interinstitutional scopes, in the clinical-therapeutic work of the health professionals, patients and relatives. The speech therapist's skills and knowledge about organic aspects of child development in the opinion of professionals enhance clinical listening.

It was concluded that without teamwork, care in CAPSij would not happen in a qualified way under the public health policies Psychosocial Care Network (PSCN) and Unified Health System (SUS) frameworks. The clinical listening is a condition of possibility of the care offered by the professionals.
It was concluded that without teamwork, care in CAPSij would not happen in a qualified way under the public health policies Psychosocial Care Network (PSCN) and Unified Health System (SUS) frameworks. The clinical listening is a condition of possibility of the care offered by the professionals.
the objective of this paper is to verify the effect of speech therapy intervention program in patients with non-fluent aphasia due to stroke in language tasks related to verbal fluency in semantic and phonological categories.

Patients with aphasia due to stroke were selected to take part in this study. Two groups were formed diagnosed patients with Broca/transcortical motor aphasia (GA), and a control group (healthy individuals). GA took a fluency verbal task (FAS, other complementary categories phonological /p/ /l/ and semantic "fruits" and "names"). These patients were all engaged in a language intervention program developed by the authors of this study. GA received speech therapy sessions (ten sessions lasting for an hour once a week), following a specific language program. After the sessions, the patients were re-evaluated.

GA had statistical significant improvement in the verbal fluency task after the speech therapy program (p-value < 0,001).

The speech language therapy program we proposed was efficient enough to show improvement in the results for GA in the verbal fluency task.
The speech language therapy program we proposed was efficient enough to show improvement in the results for GA in the verbal fluency task.
To propose a normalization model of a posturography platform in adults without changes in body balance, through descriptive analysis by age group and sex.

Cross-sectional observational study. Adults, with no changes in body balance and no vestibular complaints were submitted to 6 sensory conditions on the Horus® posturography platform. link2 The following variables were analyzed stability limit area and confidence ellipse area, trajectory length and average velocity for each condition tested. link3 The variables were analyzed by age group and sex. The equilibrium score, the sensory integration test and the equilibrium index were calculated on the conditions.

Sixty-one subjects (38.3%) and 23 (37.7%) were male, 40 (65.57%) between the ages of 20 and 40 and 21 (34.43). %) between 41 and 59 years. The area of the stability limit and pressure center variables for 6 sensory conditions tested - confidence ellipse area, trajectory length, total mean velocity and confidence ellipse ratio by the area of the stability limit were described. There was a statistically significant difference in the comparison between the area of the stability limit between sexes and between age groups, being a higher value in males and in younger patients. Regarding the analysis of the variables by each condition, there was no difference of results between the sexes and age groups.

Subjects of different sexes and age groups should be considered separately only in the analysis of the stability limit.
Subjects of different sexes and age groups should be considered separately only in the analysis of the stability limit.
to identify, in international scientific production, the main psychosocial factors in nursing work, found through the Copenhagen Psychosocial Questionnaire (COPSOQ) application.

a systematic review study of psychosocial factors at work among nursing professionals, who used COPSOQ in the assessment of work environments.

fifteen articles were identified, which highlighted as main psychosocial dimensions of nursing work demands, work organization, social relationships and leadership, work-home interface, workplace health and well-being and offensive behaviors.

the high demands for cognitive, emotional work and work pace were identified in the nursing routine. link2 Management support had a positive impact. Physical and psychological violence and shift work interfere in family life, aggravating the fatigue of these professionals. Interventions for reducing work stress presuppose the identification of psychosocial factors involved in nursing work.
the high demands for cognitive, emotional work and work pace were identified in the nursing routine. Management support had a positive impact. link3 Physical and psychological violence and shift work interfere in family life, aggravating the fatigue of these professionals. Interventions for reducing work stress presuppose the identification of psychosocial factors involved in nursing work.
to investigate the factors that are present in the work environment of the nursing team and that contribute to emergence of psychic burden in Psychosocial Care Centers III.

this is a descriptive and qualitative study carried out in three services located in Paraíba State. Data were obtained from an interview with a semi-structured script, and textual content was treated using the software Interface de R pour Analyzes Multidimensionnelles de Textes et de Questionneires.

the factors that trigger psychic burden arise primarily from pace of work, precarious physical structure, work with users in mental distress, lack of management support, insufficient multidisciplinary team and lack of clinical supervision.

the difficulties faced by nursing professionals in the work environment cause suffering at work and hinder the effectiveness and, consequently, the quality of nursing care.
the difficulties faced by nursing professionals in the work environment cause suffering at work and hinder the effectiveness and, consequently, the quality of nursing care.
to verify Burnout Syndrome prevalence among nursing technicians of an adult Intensive Care Unit and associate prevalence with sociodemographic and clinical data.

a cross-sectional study carried out in an adult Intensive Care Unit of a large public hospital in southern Brazil, between March and April/2018. Prevalence was assessed using the Maslach Burnout Inventory.

122 nursing technicians participated (aged 39±2.5 years), 76% being women. Burnout Syndrome prevalence was 19.7% and 62.9%. There was a significant association between Burnout Syndrome and depression (p=0.004), as well as Burnout Syndrome and comorbidities (p=0.033), when less conservative criteria were adopted.

the findings are relevant to professionals in this area and may contribute to adopting strategies to combat Burnout Syndrome.
the findings are relevant to professionals in this area and may contribute to adopting strategies to combat Burnout Syndrome.
to estimate prevalence and factors associated with Burnout Syndrome in intensive care nurses in a city in the state of Bahia.

a cross-sectional, population-based study carried out with 65 intensive care nurses through a self-administered questionnaire, from July to November 2016, containing sociodemographic data, lifestyle, work characteristics. To define burnout syndrome, the Maslach Burnout Inventory was used.

Burnout Syndrome prevalence was 53.6%, an association was observed with age, tobacco consumption, alcohol use, weekly night shift hours, employment relationship, having an intensive care specialist title, number of patients on duty, monthly income and considering active or high-strain job.

the results of this study can contribute to expanding the discussion on stressful working conditions in Intensive Care Units.
the results of this study can contribute to expanding the discussion on stressful working conditions in Intensive Care Units.
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