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Proof of West Earth Computer virus Blood circulation within Lebanon.
50 mg g-1, Rpred 2 = 0.84), and that for passion fruit flavor PSDs (RMSEC = 0.24 mg g-1, Rcal 2 = 0.95; RMSECV = 0.56 mg g-1, RCV 2 = 0.76; RMSEP de 0.57 mg g-1, Rpred 2 = 0.72) indicated that NIRS-PLS methodology produced reasonable results. The limits of detection and quantification obtained showed that the method is useful to detect and quantify AA in the studied samples. A new set of grape drinks was used for external prediction and the RMSEP was 0.62 mg g-1, Rpred 2 was 0.72. Based on the results, NIRS-multivariate analysis proved to be useful for quality control of AA in commercialized grape and passion fruit in PSDs and a faster, objective and environmentally friendly method alternative to standard methods. © Association of Food Scientists & Technologists (India) 2019.In the current study, we have comprehensively analyzed different kinds of pure honey which was produced in various areas in China according to δ13C-EA -IRMS (AOAC method 998.12) and δ13C-LC-IRMS (proposed by the Intertek laboratory in Europe) methods. As for the δ13C-EA -IRMS method, the study was confirmed that the C4 sugar of all authentic honey samples was qualified. Further inter-laboratory comparison experiments using the δ13C-LC-IRMS method found that all authentic honey samples had Δδ13C (‰) values within the naturally occurring range of ± 1‰ for Δδ13C (‰) fru-glu. However, about 70% samples had Δδ13C (‰) values outside the range of ± 2.1‰ for Δδ13C (‰) max., indicating that a large proportion of pure honey in China can't pass the δ13C-LC-IRMS test, although these honeys were extracted from unadulterated sources. Based on the present findings, we consider that the δ13C-LC-IRMS method is not appropriate to reliably detect adulterated honeys with C3 sugars in China. © Association of Food Scientists & Technologists (India) 2019.Grapes are one of the most highly consumed fruits across the world. In ancient Europe the leaves and the sap of grape plants has been used in traditional treatment for ages. Besides being a wellspring for vitamins and fibre, the skin and seeds of grapes are highly rich in Polyphenols specifically proanthocyanidins, which can be used as a functional ingredient to address various health issues by boosting the natural bio-processes of the body. Since, grape seeds are by product of wine making companies therefore can be easily procured. The present review article briefly describes the various pharmacological activities of grape seed extract and different experimental studies were done which supports the beneficial health qualities of the extract. Through different and various studies, it was proved that the proanthocyanidin rich grape seed extract provides benefits against many diseases i.e. inflammation, cardiovascular disease, hypertension, diabetes, cancer, peptic ulcer, microbial infections, etc. Therefore, beside from using it as a nutraceutical or cosmeceutical, as a result they may have a potential to substitute or complement in currently used drugs in the treatment of diseases by developing it into other successful pharmaceutical formulations for better future prospective. © Association of Food Scientists & Technologists (India) 2019.Phoenix dactylifera (date palm) is a member of the genus Phoenix belonging to family Arecaceae. It is widely cultivated for its edible fruits and kernels. Dates have been used for both dietary purposes as well as for their phytomedicinal impacts against the variety of diseases. Date fruits are rich in alkaloids, protein, carbohydrate, fatty acid (linoleic, lauric, palmitic, and stearic acid), carotenoids, vitamins, polyphenolic compounds, flavonoids, and tannins along with different types of nutrients like potassium, calcium, magnesium, and phosphorus. Due to the presence of the variety of phytochemicals, they have greater impact on human health. They have strong antioxidant potential. It has been proposed now as a potential source of several unique medical and industrial products. In literature, much information is available on botanical descriptions, agriculture technology, and utilization in therapeutic intervention, but a little description is accessible on phytochemical relevance, formulation strategies, nutritional impact, and bioprocess technology. Therefore, the present review provides comprehensive information on the phytochemical relevance, pharmacology/bioactivity, pharmaceutical impact, their scope in bioprocess technology and nutraceutical values of date palm. According to all collected information, every portion of the plant has some beneficial properties that can serve as a source of medicine and nutraceutical. © Association of Food Scientists & Technologists (India) 2019.A 52-year-old female presented with an asymptomatic cyst-like lesion on her right labia majora present for several years. Excision revealed a 3-mm cystic lesion containing complex networks of thin fronds of clear apocrine cells and basaloid cells, features characteristic of hidradenoma papilliferum (HP). In contrast to the medical literature, the lesion was connected to the overlying epithelium by a straight duct, a feature characteristic of apocrine glands. Searching of six different dermatopathology study sets revealed 11 cases diagnosed as HP. Histological review of the eight available cases for review revealed none that were diagnosed correctly. Six were syringocystadenoma papilliferum and two were trichoepithelioma. HP is a fascinating lesion that needs further study and requires better diagnostic criteria. Copyright © 2020 Indian Journal of Dermatology.Gastric cancer is the fourth most commonly diagnosed cancer and the second most common cause of cancer-related death worldwide. Cutaneous metastases of signet-ring cell gastric carcinoma are uncommon. Here, we report a metastatic gastric adenocarcinoma, which manifested itself as an asymptomatic scar-like lesion on the epigastric area and histopathological features of the cutaneous lesion showing signet-ring cell. Copyright © 2020 Indian Journal of Dermatology.Lymphoma over the nasal dorsum has never been reported. Herein, we report the case of a 74-year-old man who presented with a rapid swelling on the nasal dorsum. A physical examination revealed a firm, immobile, non-tender mass. Computed tomography revealed a space-occupying lesion in the subdermal layer of the nasal dorsum that was most likely a fibroma. An excisional biopsy was performed. Surprisingly, histopathological and immunohistochemical analyses identified a diffuse large B-cell lymphoma. The patient underwent seven cycles of chemotherapy comprising of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone. He responded well to the regimen. No evidence of persistent or recurrent disease had been detected during the 9 months after his last chemotherapy session. Although never reported previously, lymphoma can mimic common midline nasal soft-tissue tumors and should be considered in the differential diagnosis. Copyright © 2020 Indian Journal of Dermatology.Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing. Copyright © 2020 Indian Journal of Dermatology.Childhood granulomatous periorificial dermatitis (CGPD) is a self-limiting skin condition characterized by papular eruptions around the mouth, nose and eyes of preadolescent children. We report two cases of intractable CGPD in which patients receiving growth hormone (GH) therapy showed persistent symptoms despite multiple treatment modalities. This association may suggest the role of GH in the pathogenesis of CGPD. Copyright © 2020 Indian Journal of Dermatology.Sebaceous nevus (SN), is a skin hamartoma, combining a variety of epidermal, follicular, sebaceous, and apocrine abnormalities. Although usually present at birth, it may become apparent later in life appearing as a yellowish-brown, verrucous plaque with alopecia. SN is implicated with secondary tumors arising on the hairless plaque during the adulthood. Lichen planopilaris is a common, primary lymphocytic scarring alopecia of unknown etiology, characterized by lichenoid/interface perifollicular lymphocytic infiltrate occurring at the level of the infundibulum and the isthmus. Here, we present a case of a 48-year-old Caucasian male with lichen planopilaris lesions developing at the periphery of a preexisting SN. Our case raises the question, whether the development of lichen planopilaris was coincidental, or is it indicative of an etiologic association between the lichen planopilaris and SN. Copyright © 2020 Indian Journal of Dermatology.We report a case of a 50-year-old female who presented with multiple thick-walled vesicles involving the labia majora and minora which started developing at the age of 10 year. The vesicles extruded milky white fluid when punctured. Biochemical analysis of the fluid was consistent with chyle. Lymphoscintigraphy showed reflux of the radioactive tracer into the genitalia, thus confirming the diagnosis of primary chylous lymphangiectasia. The patient was not willing to undergo definitive surgical treatment. We report the case considering the rarity and to depict the usage of biochemical analysis of the vesicular content and lymphoscintigraphy to detect this entity. Copyright © 2020 Indian Journal of Dermatology.Becker's nevus, also known as pigmented hairy epidermal nevus, is characteristically described as a unilateral, hairy, light to dark brown macule with sharply outlined but irregular border. The etiopathogenesis of Becker's nevus is still not clearly understood. Perifollicular pigmentation has been described earlier by some authors. But, Becker's nevus presenting exclusively with follicular lesions has not been described. We are reporting a series of patients of Becker's nevus with follicular lesions. The diagnosis in all the patients was made after clinicopathological correlation. Follicular epithelium may hold a significant role in the etiopathogenesis of Becker's nevus. Copyright © 2020 Indian Journal of Dermatology.Background Mycosis fungoides (MF) is the most common primary cutaneous lymphoma. It affects usually the covered areas of the body in elderly males in 6th and 7th decades of life. CDK inhibitor Atypical dermal lymphoid infiltrate is seen along with epidermotropism. Nuclei of neoplastic cells are convoluted. The neoplastic cells demonstrate positivity for CD3 (Pan T) immunohistochemical stain. Majority show increased CD4 to CD8 ratio. The present study was done to study the clinicopathological features, which might be of help in reaching a correct diagnosis in these cases. Materials and Methods A retrospective descriptive study was conducted on 60 reported cases of MF. The retrieved slides were reviewed for clinical and histopathological features and immunohistochemical profile. Results The ages ranged from 20-84 years, mean age was 47 years. Majority (75%) of patients were male. Trunk and extremities were the sites most commonly affected. There was significant inverse correlation between epidermal thickness and tumor stage (P = 0.
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