Notes

[Chromosomal karyotypes and also C-band evaluation associated with Triatoma rubrofasciata in China].
39; 95% CI 1.04-1.84), a lower education level (aORs ranging from 1.46 to 2.47), and having one or more chronic diseases (aORs ranging from 1.43 to 2.02) to be significantly associated with reporting all three symptoms (all P ˂0.05). While long-term medication and regular exercise were the protective factors.

This study suggests that the cooccurrence of the three symptoms accounts for a certain proportion of the Chinese health check-up population. Integrated interventions that address CP and mental health cooccurrence may be an essential target for heath management in this population to tackle this considerable burden.
This study suggests that the cooccurrence of the three symptoms accounts for a certain proportion of the Chinese health check-up population. Integrated interventions that address CP and mental health cooccurrence may be an essential target for heath management in this population to tackle this considerable burden.
. Hypersexuality is a clinical condition regarding the psychopathology of sexual behavior. In this study, we aimed to investigate the role of trauma, through the post-traumatic stress-disorder (PTSD), depression, shame and guilt on the hypersexual behavior.

. Through an online platform, a convenience sample of 1025 subjects was recruited (females n=731; 71.3%; males 294; 28.7%; age 29.62±10.90). Recruited subjects compiled a psychometric protocol composed by the Hypersexual Behavior Inventory (HBI) to assess hypersexuality, the International Trauma Questionnaire (ITQ) for PTSD, the Patient Health Questionnaire (PHQ-9) to evaluate depression and the State Shame and Guilt Scale (SSGS) for shame and guilt. Then a mediation/moderation model was performed for the data analysis.

. There was a statistically significant direct effect of post-traumatic symptoms (ITQTotal) on hypersexual behavior (HBTotal). Furthermore, indirect effects were also statistically significant, providing support to the hypothesis thatidered as a reactive form of a major affective psychopathology representing a tip of the iceberg hiding the real issues of a suffering personality. Clinicians and researchers should therefore consider hypersexual behavior in the light of a symptomatic manifestation of a major psychopathology involving the affective aspects of personality.
Anhedonia, a key symptom of depression and schizophrenia, has emerged as a potential endophenotype. The aim of this study was to evaluate the psychometric properties of a Chinese version of the Snaith-Hamilton Pleasure Scale(SHAPS), a self-report anhedonia scale, in a non-clinical sample and clinical sample inclusive of major depressive disorder (MDD), schizophrenia, or a personality disorder.

A total of 4,722 undergraduate students and 352 clinical patients participated in this study. Internal consistency was assessed by calculating Cronbach's α and mean inter-item correlation (MIC) values. Test-retest reliability and convergent validity were assessed with Pearson r coefficients. The best fitting of six potential factor-structure models was determined by confirmatory factor analysis (CFA). Measurement invariance across genders and samples was determined by multi-group CFA.

Internal consistency of the Chinese version of the SHAPS was acceptable in non-clinical (Cronbach's α=0.90) and clinical (Cronbach's α=0.91) samples. Four-week interval test-retest reliability was 0.60. Moreover, the Spanish four-factor structure had the best fit indexes in both samples. Scalar invariance was established across genders as well as across non-clinical sample and clinical sample. SHAPS was significantly related with the Temporal Experience of Pleasure Scale (TEPS) and Beck Depression Inventory (BDI).

There was a restricted scope of convergent validity and the size of clinical sample is relatively small, psychometric properties in elderly sample is also required.

The Chinese version of the SHAPS is a reliable, effective, simple and convenient tool for assessing and screening for anhedonia.
The Chinese version of the SHAPS is a reliable, effective, simple and convenient tool for assessing and screening for anhedonia.
Adolescents with bipolar disorder (BD) are often misdiagnosed with major depressive disorder (MDD), which delays the introduction of appropriate treatment resulting in adverse outcomes. This study examined the psychometric properties of the 33-item Hypomania Checklist (HCL-33) and its accuracy to distinguish BD from MDD in adolescents.

A total of 248 participants (171 MDD and 77 BD patients) were recruited from a university-affiliated hospital in China. Depression was measured with the Hamilton Depression Rating Scale. All participants completed the assessment with the HCL-33.

A two-factor structure was found for the HCL-33, which explained 30.2% of the total variance. The internal consistency and split half reliability of the total scale were acceptable. The optimal cut-off value of 18 generated sensitivity of 0.52 and specificity of 0.73 for distinguishing BD from MDD.

The HCL-33 seems to be a useful screening instrument to distinguish BD from depressed adolescents. However, considering certain less than robust psychometric properties, the HCL-33 needs to be modified and further refined for adolescent patients.
The HCL-33 seems to be a useful screening instrument to distinguish BD from depressed adolescents. However, considering certain less than robust psychometric properties, the HCL-33 needs to be modified and further refined for adolescent patients.Comorbid personality disorders are common in patients with major depressive disorder (MDD). Individuals with comorbid borderline personality disorder (BPD) may be less responsive to electroconvulsive therapy (ECT), but it remains unclear whether BPD affects responsiveness to transcranial magnetic stimulation (TMS). We sought to investigate the association between BPD and response to TMS. We conducted a retrospective analysis of individuals receiving TMS (n=356) at McLean Hospital. We also included individuals receiving ECT (n=1434) as a control. All individuals completed the McLean Screening Instrument for BPD (MSI-BPD) at baseline. Response to treatment was measured by the Quick Inventory of Depression Symptomatology Self-Report (QIDS-SR). We performed general linear models (GLMs) to assess the effect of BPD on treatment response to TMS and ECT. At baseline, the ECT group had a higher average QIDS-SR score (21.4 vs. 20.3, p less then 0.05). For both treatment groups, the number of treatments had a significant effect on depression severity. For the TMS group, there was no significant Group x Time interaction on QIDS-SR score (p=0.18). However, for individuals receiving ECT, there was a significant Group x Time interaction on QIDS-SR score (p=0.02), suggesting that BPD significantly impaired response. These results suggest that borderline personality traits did not affect treatment response to TMS for MDD. BPD traits modestly predicted response to ECT, which is consistent with the literature. These results require replication in a clinical trial.
Almost half of the patients with a bipolar disorder (BD) have anxiety disorder(s) (AD) during their lifetime, but feasible measures for all AD are few. Furthermore, cognitive impairments can compromise reliability of existing scales, since many are needed for full coverage. Thus, we investigated how reliably patients responded to anxiety scales and any symptom overlap to propose future improvements to anxiety assessments.

We collected 152 observations in patients with BD with theClinically Useful Anxiety Outcome Scale, Social Phobia Inventory, Panic Disorder Severity Measurement, and Trauma Screening Questionnaire (in total, 57 items). The scales were analyzed as a set in a Rasch model.

During our analyses, we found indication that BD outpatients had difficulty differentiating response options to 70% (40/57) of items which were rescored or deleted. Only one case was misfitting (-2.65±.41). In total, 22 items were locally dependent and one indicated misfit. The final model included 25-items and fit the Rasch model (χ
=35.92, DF=50, p=.93). The model was unidimensional, without losing appropriate associations with depression (r=0.62), suicidality (r=0.37), and hypomania (r= -0.01).

Bolstering the size of less frequent subgroups should be accomplished in future work.

A unidimensional rather than categorical approach to severity of anxiety might be both useful and feasible in this population. selleck chemicals Further development of screens is necessary to enable systematic screening and measurement of anxiety in BD.
A unidimensional rather than categorical approach to severity of anxiety might be both useful and feasible in this population. Further development of screens is necessary to enable systematic screening and measurement of anxiety in BD.
Default mode network (DMN) has been widely reported to be altered in bipolar disorder during major depressive episode (BDD). Recent studies supported the idea that DMN is not an unitary system, but composed of smaller and distinct functional subsystems. The current study aimed to investigate the abnormal functional connectivity (FC) patterns of DMN subsystems in BDD.

Seed-based FC method was applied to extract 11 DMN components in resting-state functional magnetic resonance imaging data acquired from 40 patients with BDD and 63 demographically matched healthy controls.

Patients showed reduced FC between precuneus and all three DMN subsystems. Additionally, in the midline core, patients revealed increased FC between posterior cingutate cortex (PCC) seed and lateral orbitofrontal cortex. In the dorsomedial prefrontal cortex and medial temporal lobe subsystems, patients demonstrated increased FC with sensorimotor, visual, and salience network regions. Furthermore, the abnormal FC between the PCC seed and precuneus was correlated with high pessimism.

Our sample size is relatively small, limiting the power to detect subtle group differences and significant correlations between brain connectivity and clinical variables. In addition, most of our patients have been treated with medications.

Our findings revealed the abnormal FC patterns of DMN subdivision circuits and highlighted these abnormalities were associated the pathological mechanisms in BDD.
Our findings revealed the abnormal FC patterns of DMN subdivision circuits and highlighted these abnormalities were associated the pathological mechanisms in BDD.
Life Goals Programme (LGP) was developed as a psychological intervention for bipolar disorder, with its structured 6-session psychoeducation phase (Phase 1) targeting understanding of the disorder, medication adherence, early warning signs, and coping with symptoms and triggers. The present study tested the efficacy of Phase 1 of the LGP on symptom recovery and moment-by-moment mood stability, as well as medication adherence and quality of life.

Adults with bipolar disorder were randomly allocated to the LGP condition (six weekly group sessions) or the waitlist condition (six weeks of standard care, followed by the same LGP intervention). Participants were assessed before and after treatment, and at 6-month follow up. Waitlist participants were additionally assessed at baseline. Assessment included a clinical interview (SCID, MADRS, YMRS, and HAM-A), self-reported questionnaires, and 6-day experience sampling assessment on a mobile device.

64 out-patients with bipolar disorder (44 Bipolar I and 20 Bipolar II subtypes) participated in this study.
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