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WC cut-offs were higher for South Asian women than men. IDF-based WC cut-offs corresponded to a higher prevalence of the MetS across sex and ethnic groups, compared with Kuwait-specific cut-offs. Any of the assessed anthropometric indices can be used in screening of diabetes and ≥3 CVD risk factors in Kuwaiti Arab and Asian populations. ROC values were similar. The WC threshold for screening the MetS in Kuwaiti Arabs and South Asians is higher for women.Tuberous sclerosis complex is a rare multisystem genetic disorder characterised by the growth of numerous tumour-like malformations in many parts of the body including skin, kidneys, brain, lung, eyes, liver, and heart. Mutations in the TSC1 or TSC2 genes have been reported to cause disruption in the TSC1-TSC2 intracellular protein complex, causing over-activation of the mammalian target of rapamycin protein complex. In this study, we present a 3-month-old male infant diagnosed with tuberous sclerosis, bilateral neurosensorial hearing loss, Wolff-Parkinson-White syndrome on electrocardiography, multiple cardiac rhabdomyomas with severe stenosis in the left ventricular outflow tract, who responded well to the Everolimus therapy.The northern section of the Caspian Sea and lower reaches of the Zhaiyk (Ural) River is an important fishery for Kazakhstan. In the present study, a total of 1597 individuals of ten fish species were analysed. The fish were caught over three years, from 2018 to 2020. For each species studied - Abramis brama, Alosa saposchnikowii, Atherina boyeri caspia, Carassius gibelio, Chelon auratus, Cyprinus carpio, Leuciscus aspius, Rutilus caspius, Sander marinus and Sander volgensis - between 100 and 200 individuals were examined. A series of generalized linear models (GLMs) were used to examine the association between individual parasite intensity of infection and the Fulton index, age, year the fish was captured, where the fish was captured (northern Caspian or Zhaiyk River) and sex. For each GLM, the best-fitting probability distribution was used -either Poisson, zero-inflated Poisson, negative binomial or zero-inflated negative binomial. For some fish/parasite species, an increased Fulton index was associated withnt with either the fish being exposed to parasite infection or not; and, if exposed, infection was a random process. Other parasites had a negative binomial distribution, consistent with the entire fish population being exposed, but the infection process was clumped or there were variations in the susceptibility of infection between fish. Finally, some of the parasites had a zero-inflated negative binomial distribution, which can be interpreted as part of the fish population not being exposed and the remainder of the population being exposed to a clumped or aggregated infection process and/or a variation in individual susceptibility to infection.
The purpose of this study was to investigate how old persons perceived their life to be, how they viewed the ageing process and their need of health care and societal support.

The purpose of WHO's Healthy Ageing strategy and development of age-friendly environments is to support physiological and psychosocial changes in old persons by facilitating basic needs. Interventions to operationalize these needs in older people living at home are often developed from a professional perspective and to a small extent involves the perceptions, experience and expectations of the older persons.

This qualitative study has an explorative design using focus group discussions to collect data. In all, 34 persons between 69 and 93 years of age participated in seven group discussions. The interviews were analyzed using inductive manifest content analysis.

The main results suggest that most old persons enjoyed life and wished it to continue for as long as possible. see more Important was to sustain networks and to feel useful. Unexpected changes were described as threats and the need to use health care services was associated with illness and being dependent. The result is presented in three categories with sub-categories 'Embracing life', 'Dealing with challenges' and 'Considering the future'.
The main results suggest that most old persons enjoyed life and wished it to continue for as long as possible. Important was to sustain networks and to feel useful. Unexpected changes were described as threats and the need to use health care services was associated with illness and being dependent. The result is presented in three categories with sub-categories 'Embracing life', 'Dealing with challenges' and 'Considering the future'.
Based on a cohort from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), we aimed to evaluate the relationship between sleep duration and the incidence of cognitive impairment among older Chinese adults.

We conducted a prospective analysis based on 3692 participants from the CLHLS at baseline (in 2011), and as a 3-year follow-up (till 2014), 531 participants (14.4%) had cognitive impairment, which was defined as a Mini-Mental State Examination score <24. Sleep duration was classified into three groups short (≤5 hours/day), normal (>5 but <10 hours), and long (≥10 hours/day). A logistic regression model was used to examine the association between baseline sleep duration and cognitive impairment after adjusting for sociodemographic data, living habits, and health conditions.

Five hundred sixty-two participants (15.2%) were in the short-duration group, and 608 participants (16.5%) were in the long-duration group. After adjusting for multiple potential confounders, compared with normal sleep duration, long sleep duration was associated with the incidence of cognitive impairment (OR = 1.309, 95% CI 1.019-1.683), especially among men (OR = 1.527, 95% CI 1.041-2.240) and those having a primary and above education level (OR = 1.559, 95% CI 1.029-2.361). No significant association was observed between short sleep duration and cognitive impairment (OR = 0.860, 95% CI 0.646-1.145).

Excessive sleep may increase the risk of cognitive impairment in older individuals. It may be a suggestive sign of early neurodegeneration and may be a useful clinical tool to identify those at a higher risk of progressing to cognitive impairment.
Excessive sleep may increase the risk of cognitive impairment in older individuals. It may be a suggestive sign of early neurodegeneration and may be a useful clinical tool to identify those at a higher risk of progressing to cognitive impairment.
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