Notes

A new mobile mindfulness intervention regarding crisis section employees to boost stress as well as well-being: Any qualitative research.
To analyse the role of multiparametric magnetic resonance imaging (mpMRI) ultrasound (US)-guided fusion biopsy (FB) in patients with low-risk prostate cancer (PCa) under active surveillance (AS).

Our retrospective study included 47 patients under AS who consecutively underwent both FB and standard biopsy (SB), from May 2015 until November 2017. We defined FB as a transrectal US-guided biopsy based on mpMRI. The primary endpoint was to assess the rate of concordance between FB and SB in terms of diagnostic yield, as well as the rate of Gleason Score upgrading/downgrading between the two techniques. Cohen's kappa coefficient (κ) was applied to test the concordance between FB and SB.

The median (interquartile range [IQR]) follow-up was 20 (13-37) months. The median (IQR) number of cores taken was 13 (12-14) at SB and 4 (4-6) at FB. Overall, FB missed 12/47 (26%) PCa diagnoses compared to SB. There was concordance between SB and FB in 64% of the patients. The




κ



showedMRI multiparametric MRI; (cs)PCa (clinically significant) prostate cancer; PI-RADS Prostate Imaging-Reporting and Data System; PRIAS Prostate Cancer Research International Active Surveillance; ROI region of interest; SB standard biopsy.
To perform a time-to-complication analysis for radical prostatectomy (RP) and computing risk factors for these complications, as RP is established as a first-line treatment for localised prostate cancer with excellent oncological outcomes but is not without its complications.

We used the National Surgical Quality Improvement Program (NSQIP) database to analyse data of patients who underwent RP, between 2008 and 2015, with the primary endpoint of time-to-complications. Categorical variables were analysed using descriptive statistics and continuous variables were recorded as medians and interquartile ranges (IQRs) such as timing of complications. Multivariable regression analyses were used to analyse time-to-complication and its effect on other outcomes. A
<0.05 was defined as statistically significant.

The overall 30-day complication rate was 7.54% and was equally distributed before and after discharge. Bleeding/transfusion (3.37%), urinary tract infection (1.58%), deep venous thrombosis (DVT; 0.74; LOS length of stay; NSQIP National Surgical Quality Improvement Program; OR odds ratio; RP radical prostatectomy.
ACS American College of Surgeons; BMI body mass index; DM diabetes mellitus; DVT deep venous thrombosis; Hct haematocrit; IQR interquartile range; LOS length of stay; NSQIP National Surgical Quality Improvement Program; OR odds ratio; RP radical prostatectomy.
To assess the prevalence of clinical orchitis in patients with coronavirus disease 2019 (COVID-19).

This was a retrospective clinical observational study using data of male patients who were admitted to hospital with COVID-19 confirmed by reverse transcriptase polymerase chain reaction testing between 1 March and 4 May 2020. Patients were categorised according to age groups and disease severity. find more Sociodemographic information and general clinical symptoms of COVID-19 and orchitis were collected.

We identified a total of 253 male patients, with a mean (range) age 43 (1-78) years. Patients were followed-up until their recovery or for 21days. We did not observe any symptoms or signs of orchitis in any patient during follow-up across all age groups and different disease status.

Although we did not identify any patients with COVID-19 with symptoms or signs of orchitis, such an association cannot be excluded, and further studies are needed to validate our hypothesis and exclude any association at a molecular level.

ACE2 Angiotensin-converting enzyme 2; COVID-19 coronavirus disease 2019; CRP C-reactive protein; ESR erythrocyte sedimentation rate; HIV human immunodeficiency virus; IRB, Institutional Review Board; ISH,
hybridisation; RT-PCR reverse transcriptase-PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus-2; TMPRSS2 transmembrane protease, serine 2; WBC white blood cell.
ACE2 Angiotensin-converting enzyme 2; COVID-19 coronavirus disease 2019; CRP C-reactive protein; ESR erythrocyte sedimentation rate; HIV human immunodeficiency virus; IRB, Institutional Review Board; ISH, in situ hybridisation; RT-PCR reverse transcriptase-PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus-2; TMPRSS2 transmembrane protease, serine 2; WBC white blood cell.
To assess feasibility of robot-assisted laparoscopic radical nephrectomy (RALRN) and inferior vena cava thrombectomy (IVCT) in treating renal tumours with level I-III IVC thrombi and to assess their outcomes.

We conducted a retrospective analysis of RALRN-IVCTs, involving four centres across India, from September 2015 to June 2019. We analysed patients who underwent RALRN-IVCT for level I-III thrombi according to the Mayo classification. The total operative duration with console time, length of hospital stay, preoperative and postoperative creatinine, IVC clamp time and intraoperative blood loss were recorded.

Of the 13 patients that underwent RALRN-IVCT, five had a level I thrombus, seven had level II, and one had a level III thrombus. In all, 11 of the patients had right-sided tumours and the remaining two had left-sided tumours. The mean (SD) age of the patients was 56.5 (12.3) years, the mean (SD) operative time was 329.5 (97.22) min, the mean (SD) console time was 222.5 (70) min, the mean (SD) bloocal nephrectomy.
(a) To assess the inter-observer variability amongst surgeons performing percutaneous nephrolithotomy (PCNL) and radiologists for the Guy's Stone Score (GSS) and S.T.O.N.E. (stone size [S], tract length [T], obstruction [O], number of involved calyces [N], and essence or stone density [E]) nephrolithometry score; (b) To determine which scoring system of the two is better for predicting the stone-free rate (SFR) after PCNL.

Patients undergoing PCNL between February 2016 and September 2016 were prospectively enrolled. Preoperative computed tomography was done in all patients. The GSS and S.T.O.N.E. nephrolithometry score were independently calculated by eight surgeons and four radiologists. The patients were operated on by one of the surgeons (all were consultants). The Fleiss' κ coefficient was used to assess agreement independently between the surgeons and radiologists. Receiver operating characteristic (ROC) curves were constructed for predicting the SFR using the average of the scores of the surgeons and radiologists separately.
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