Notes

Heart stroke Reduction within Atrial Fibrillation.
Participants in a pre-test of the latest cross-culturally adapted version of ProQOL V verified the readability, comprehensibility and suitability of the instruments' items. After completion of the validation of the ProQOL V, it will become available to Greek researchers.
High quality self-report measures are necessary in evidence-based health and social care research and practice. Participants in a pre-test of the latest cross-culturally adapted version of ProQOL V verified the readability, comprehensibility and suitability of the instruments' items. After completion of the validation of the ProQOL V, it will become available to Greek researchers.
COVID-19 pandemic suddenly affected all countries and health care systems from different perspectives including severe disruption of chronic disease services including diabetes. Diabetes is a serious condition and highly present in Bosnia and Herzegovina population, so provision of diabetes care is a important part of good control. Selleck PF-06882961 Countries had different responses to adopt diabetes care under new circumstances as well as Bosnia and Herzegovina.

To investigate and evaluate the impact of the COVID-19 pandemic on the provision of diabetology care in Bosnia and Herzegovina from the perspective of patients and diabetologists.

Online survey for diabetologists and patient organizations have been developed with adopted question for different perspectives. The survey has been conducted online early September 2020. Collected data were analyzed in SPSS software for descriptive statistics.

25 diabetologists and 24 diabetes patient organizations responded. 72% of diabetologists believe that pandemic has partiallyimilar to other countries.
Diabetes and depression are two common and major non-communicable diseases with significant disease burdens worldwide.

The aim of this study is to obtain the association among A1C levels and symptoms of depression in patients with type 2 diabetes in family medicine offices.

This cross-sectional study was carried out between June 2016 and July 2017. We recruited 150 adults with type 2 diabetes from various family medicine offices. The study questionnaire had two parts; the first one for participants and the second one for family medicine physicians. Participants completed the part of the questionnaire with the PHQ-9 scale and questions regarding demographic data. Family medicine physicians completed the part of the questionnaire with questions concerning clinical data. A univariate and multivariate linear regression analysis was conducted to identify significant predictors of depressive symptoms revealed by the PHQ-9 score.

Multiple linear regression showed that the level of A1C was a significant predictor of the PHQ-9 score in all three models. Increases in the A1C level were followed by increases in depressive symptoms. Other significant predictors of a positive PHQ-9 score were smoking, level of education and income.

The level of A1C as an indicator of glycemic control has been shown to have a significant association with the scores of the PHQ-9 questionnaire, which identifies the intensity of symptoms of depression. An increase in the level of A1C is followed by an increase in the intensity of symptoms of depression.
The level of A1C as an indicator of glycemic control has been shown to have a significant association with the scores of the PHQ-9 questionnaire, which identifies the intensity of symptoms of depression. An increase in the level of A1C is followed by an increase in the intensity of symptoms of depression.
Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic rheumatic disease, very complex, with many different forms, progressive course, with pronounced changes in the joints, still unknown etiology and poorly understood pathology. Assessing of structural change can be done with proposed scores which observe changes on wrist and wrist joints, as a Sharp score.

To examine the correlation between Anti-Citrullinated Protein Antibodies (Anti-CCP) values and Sharp score, and to determine the importance of Sharp score in the progression of RA.

The study had prospective character and followed patients in the period from January 1, 2017 to December 31, 2017. The study included 40 patients with RA. At the beginning of the follow-up of patients, X-ray of hands and feet were performed.

Out of total of 40 patients, 34 or 85% had a follow-up examination after one year. Of these, 14 patients (41.2%) were reported to have complications. The subjects were divided into two groups according to Anti-CCP values. Fi = 0.001), indicating that the Sharp score reflects disease progression.

Anti-CCP values are also directly correlated with the Sharp score, which should be routine in both initial and repeated examination of a patient with RA. Sharp's score represents a marker of progression as well as of therapeutic modality of RA.
Anti-CCP values are also directly correlated with the Sharp score, which should be routine in both initial and repeated examination of a patient with RA. Sharp's score represents a marker of progression as well as of therapeutic modality of RA.This article reports on the findings of a 10-month study designed to collaboratively explore the impact of the arrival of Syrian refugee newcomers in 2015-2016 on the way local communities support newcomers. Waterloo Region, a mid-size urban centre in Ontario, Canada, was the focus of study. The study used a mixed-method design involving four methods (document review, key informant interviews, organisational survey focus groups). Findings are presented following a systems change analytical framework that included (1) an emerging vision for local refugee support in the Waterloo Region, (2) the adaptation of local structures, (3) the emergence of collaborative processes and (4) an overall assessment of impact. Three main lessons are discussed. The first lesson demonstrates how local systems change is negotiated within a broader migration landscape (contextualizing local systems change). The second lesson acknowledges that a community's historical migration response can be a springboard for local change (initiating local systems change). The third lesson suggests that expanding and coordinating community engagement in the refugee support system is integral for lasting change (sustaining local systems change). Combined, these lessons provide a comprehensive analysis into how local communities can be adaptive in supporting refugee newcomers.Following the Syrian conflict that began in 2011, Lebanon received more than one million refugees including 44,000 Palestinian refugees from Syria (PRS). PRS children were integrated into existing schools run by the United Nations Relief and Works Agency (UNRWA). Despite efforts by UNRWA to integrate the newly displaced into its services in Lebanon, only 58% of 6-18-year-old PRS children were enrolled in school in 2014. Informed by ecological systems theory, we examined the role of parental characteristics in determining school enrollment among PRS children following displacement into Lebanon. Utilizing data from the 2014 UNRWA Vulnerability Assessment (N = 12,378 6-18-year-old children), we specified crude and adjusted logistic regression models to predict child school non-enrollment including a set of variables on head of family characteristics (gender, age, education, and presence/absence of chronic disease) and post-displacement household characteristics (crowding, wealth, camp residence, region, and type of dwelling). The results show that, adjusting for household characteristics, a child living in a family whose head has secondary education or higher is more likely to be enrolled in school compared to one living in a family headed by someone with less than secondary education. Parental education remains the strongest predictor of child school enrollment despite displacement-related household disadvantage. To break the cycle of intergenerational educational disadvantage, it is critical for UNRWA to proactively design school retention programs for PRS children living in families whose head had limited access to education.
The online version contains supplementary material available at 10.1007/s12134-020-00793-y.
The online version contains supplementary material available at 10.1007/s12134-020-00793-y.Mycotoxin contamination in feedstuffs is a worldwide problem that causes serious health issues both in humans and animals, and it contributes to serious economic losses. Deoxynivalenol (DON) and T-2 toxin (T-2) are major trichothecene mycotoxins and are known to challenge mainly intestinal barrier functions. Polyphenolic rosmarinic acid (RA) appeared to have antioxidant and anti-inflammatory properties in vitro. The aim of this study was to investigate protective effects of RA against DON and T-2 or combined mycotoxin-induced intestinal damage in nontumorigenic porcine cell line, IPEC-J2. It was ascertained that simultaneous treatment of DON and T-2 (DT2 1 μmol/L DON + 5 nmol/L T - 2) for 48 h and 72 h reduced transepithelial electrical resistance of cell monolayer, which was restored by 50 μmol/L RA application. It was also found that DT2 for 48 h and 72 h could induce oxidative stress and elevate interleukin-6 (IL-6) and interleukin-8 (IL-8) levels significantly, which were alleviated by the administration of RA. DT2 administration contributed to the redistribution of claudin-1; however, occludin membranous localization was not altered by combined mycotoxin treatment. In conclusion, beneficial effect of RA was exerted on DT2-deteriorated cell monolayer integrity and on the perturbated redox status of IPEC-J2 cells.Atrial fibrillation (AF) is a highly prevalent cardiac arrhythmia characterized by atrial remodeling. Complement C1q tumor necrosis factor-related protein 3 (CTRP3) is one of the adipokines associated with obesity, diabetes, and coronary heart disease. The association between plasma CTRP3 levels and AF is uncertain. The aim of this study was to investigate whether plasma CTRP3 concentrations were correlated with AF. Our study included 75 AF patients who underwent catheter ablation at our hospital and 47 sinus rhythm patients to determine the difference in plasma CTRP3 concentrations. Blood samples before the ablation were collected, and ELISA was used to measure the concentrations of CTRP3. Plasma CTRP3 concentrations were significantly lower in AF patients compared with control group (366.9 ± 105.2 ng/ml vs. 429.1 ± 100.1 ng/ml, p = 0.002). In subgroup studies, patients with persistent AF had lower plasma CTRP3 concentrations than those with paroxysmal AF (328.3 ± 83.3 ng/ml vs. 380.0 ± 109.2 ng/ml, p = 0.037). The concentrations of plasma CTRP3 in the recurrence group after radiofrequency catheter ablation of AF were lower than those in the nonrecurrence group (337.9 ± 77.3 ng/ml vs. 386.6 ± 108.1 ng/ml, p = 0.045). Multivariate regression analysis revealed the independent correlation between plasma CTRP3 level and AF. Plasma CTRP3 concentrations were correlated with the presence of AF and AF recurrence.
Infections are an important cause of morbidity and mortality for acute lymphoblastic leukemia (ALL). However, the reports regarding risk factors of induction-related infection are roughly unknown/limited in adult T-ALL during induction chemotherapy.

We performed a retrospective cohort study for the prevalence and risk predictors of induction-related infection among consecutive T-ALL patients (
= 97) enrolled in a PDT-ALL-LBL clinical trial. Of 97 patients with T-ALL enrolled in the trial, 46 were early T-cell precursor (ETP) ALL and 51 were non-ETP ALL.

When compared with non-ETP, ETP ALL subtype was characterized with lower neutrophil count (1.35 × 10
/L vs. 8.7 × 10
/L,
< 0.001) and lower myeloid percentage in the bone marrow (13.35% vs. 35.31%,
= 0.007). Additionally, ETP ALL had longer neutropenia before diagnosis (
< 0.001), as well as during induction chemotherapy (
< 0.001). Notably, the ETP cohort experienced higher cumulative incidence of clinically documented infections (CDI; 33.
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