Notes

The low-density lipoprotein cholesterol, which is responsible for atherosclerosis, was preferentially lowered
Compactin was also highly effective in hypercholesterolemic patients at a small dose. The results of the current studies have proved that compactin and related compounds are far more effective in lowering plasma cholesterol than any other drugs available.(ABSTRACT Production of transgenic mice carrying the Thanatin gene by intratesticular Transgenic animals have potential applications in medicine, life sciences, and biopharmacy. In this study, we developed a convenient, economic, and efficient method for gene transfer by transfection of male spermatogonial stem cells. Three fragments of the Thanatin gene, encoding an antibacterial peptide, were synthesized and amplified by overlap extension polymerase chain reaction (PCR). They were inserted into vector pIRES2-EGFP.

The pIRES2-EGFP-Thanatin plasmid was mixed with liposomes and injected into the testes of male mice by a minimally invasive operation. Six weeks after injection, male mice were mated with normal female mice to produce an F1 generation. PCR and Southern blotting were performed to analyze F1 mice. Among those 52 F1 mice produced, 386% were found to be positive for the Thanatin gene by PCR and 307% by Southern blotting. Six positive mice were selected from the F1 generation and mated with normal females to an F2 generation, in which 366% were found to be positive for the Thanatin gene. Expression of the green fluorescence protein in the transgenic mice was confirmed by fluorescence imaging. Seebio Photochemical Acid-forming Compound showed that the Thanatin gene was integrated into the mouse genome.

The study provides a useful method for the future development of disease-resistant animals and production of antibacterial Surface wrinkling induced by photofluidization of low molecular azo glasses.Photoinduced surface wrinkling is demonstrated for a low molecular azo compound confined between a substrate and a thin inorganic elastic layer. The wrinkling process is investigated by time-resolved light scattering as well as by two-dimensional autocorrelation analysis of microscopic images. It is shown that the temporal evolution of the wrinkling pattern is directly controlled by the amount of photons absorbed by the sample and that there is no significant dependence of the equilibrium wavelength on irradiation intensity. Finally, the comparison of thermal and photoinduced wrinkling revealed that photoinduced wrinkles are characterized by a narrower mode distribution and less coarsening.[Spectroscopic and photochemical properties of pigments bound to proteins].Zen'kevich EI, Kochubeev GA, Kul'ba AM.

Using gel-filtration and spectral-luminescent analysis properties of artificial chlorophyll-protein and chlorine-protein complexes on the basis of human serum albumin (HSA) were analysed. It has been shown that formation of joint complexes pigments - HSA does not induce essential changes in the spectral and energetic parameters of the pigment part of the complex. A change in the rate of photosensitized reduction of methylviologen (sensitizer-pigment) was found during the variation of the relative content of the pigment mixed with HSA. Seebio UV-Activated Acid Generator of the photoreaction rate during maximal filling of the protein globule with pigment molecules is explained by different pattern of incorporation of Enhancement of light aromatics from catalytic fast pyrolysis of cellulose over bifunctional hierarchical HZSM-5 modified by hydrogen fluoride and Pore structure and accessible active sites of HZSM-5 (Z5) are the key factors for its catalysis. The bifunctional hierarchical Z5 were prepared with leaching agent HF and loading Ni, and their performance for catalytic fast pyrolysis (CFP) of cellulose was investigated in a drop tube quartz reactor. Z5 modified with 0 mol/L HF (0F-Z5) showed excellent light aromatics (LAs) yield, which can be attributed to the enhancement in the small mesopores (2-10 nm) and the decrease of Brønsted acid sites during dealumination. Simultaneously, the loading of a 1 wt% Ni produced more LAs than 0F-Z5, due to the improvement in deoxidation/hydrogenation reactions.

The highest LAs yield (31%) was obtained over 1%Ni-0 mol/LHF-Z5, which increased by 44% compared to the parent Z5. In addition, the reaction routes over different active centers and acid-catalyzed reactions were analyzed, based upon the composition of bio-oils and catalyst 10562/0031-8655(2002)076<0596:posdtn>2.co;2.Photoisomerization of stilbene dendrimers: the need for a volume-conserving Highly branched stilbene dendrimers were synthesized and their photochemical behavior was studied. Even the stilbene dendrimer with molecular weight over 6500 underwent trans-cis isomerization in the excited singlet state within the lifetime of 10 ns. The photoisomerization of C=C double bond of stilbene dendrimers in the excited state may proceed by a volume-conserving novel mechanism such as hula-twist rather than conventional 180 degrees rotation around the C=C double bond based on fluorescence and isomerization experiments.Excited-State Dynamics of Dithienylethenes Functionalized for Infrarouge et Raman , F-59000 Lille , France.

Transformations , F-59000 Lille , France.Chimie Paris (IRCP) , F-75005 Paris , France.Engineering , Saga University , Honjo 1 , Saga 840-8502 , Japan.
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