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Mesothelioma and Asbestos
Asbestos is a natural mineral that is made up of long, thin fibres. Workers who are regularly exposed to asbestos may develop lung diseases like mesothelioma.
The symptoms of these diseases might not be evident for a long time after exposure to asbestos. Different asbestos types may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma, a form of cancer, that affects the outer lung lining (pleura). It is the most frequent mesothelioma type and accounts for 70% to 79% of diagnosed cases. The condition can cause chest pain, shortness of breathe and a feeling heaviness.
This type of cancer is usually caused by exposure to asbestos, which is a grouping of minerals that are composed of microscopic fibers. When inhaled, these fibers cling to the lungs and cause irritation that causes scarring and DNA mutations. The pleura covers the lungs and chest cavity and therefore, these irritations could affect both the lungs and the heart of a person. Mesothelioma symptoms typically don't show until 30 to 50 years after exposure.
The most commonly reported symptoms of pleural mesothelioma are chest pain and breath shortness. Some patients may also suffer from chest tightness or coughing. They may also experience difficulty breathing. People who suffer from this cancer usually have previous exposure to asbestos in the workplace. Manufacturing, construction, and shipbuilding are the most common occupations which put people at risk chance of developing pleural mesothelioma. People who served in the military are at a greater risk due to the frequent use of asbestos in Navy vessels and Army bunkers.
The TNM (tumors lymph nodes and metastases staging system) is the most common staging system for the pleural cancer. The stage a patient is in at diagnosis will help their doctor determine the most effective treatment plan for them. For instance, patients suffering from mesothelioma that is pleural in stage three or four have a worse prognosis than patients with lower stages. Stage four mesothelioma is often spread to the liver, diaphragm or even a person's heart. This can make the cancer more difficult to treat, and increase the chance of complications for the patient.
Peritoneal Mesothelioma
Unlike pleural mesothelioma, which develops in the lung lining, peritoneal mesothelioma is found in the peritoneum - an elongated membrane that covers the abdominal cavity as well as organs such as the intestines and liver. Like pleural mesothelioma, peritoneal mesothelioma is caused by asbestos exposure. Only 300-500 cases are diagnosed annually, which is less than pleural asbestosis.
As with pleural asbestosis, symptoms can take several years to show. Patients typically suffer from abdominal pain and may also have a lump in their abdomen. This kind of mesothelioma can cause nausea, weight loss, and fever. A lot of these symptoms can be misinterpreted as gastrointestinal issues and can lead to a misdiagnosis.
Doctors can identify mesothelioma by examining the patient's medical history and conducting a physical exam. They may also employ imaging tests like Xrays, CT scans and PET/CT scans to help find mesothelioma. These tests can reveal tumors and other signs of cancer which aren't visible on X-rays.
The results of these tests allow doctors to diagnose mesothelioma and determine the stage. They also offer treatment options. Staging is determined based on the type of cells and whether or whether the cancer has spread to other regions of the body.
The most important mesothelioma-related risk factor is exposure to asbestos. People who have worked in professions that involve asbestos, like plumbing, electrical work, manufacturing or construction, are at a higher risk of developing the disease. However, even if people do not work in these areas, they can still be exposed to asbestos through family members or through other sources. Anyone who suspects that they may be at risk should talk to an expert. A mesothelioma specialist can assist those who have had a experience with asbestos to understand more about their risk.
Risk Factors
Asbestos exposure is the primary risk factor for mesothelioma which accounts for as much as 80 percent of all cases. Exposure to asbestos may occur through work, military service or through living with a person who works with asbestos or was previously exposed to doing such. Asbestos particles can be inhaled by people who are exposed to asbestos. They can cause irritation to the linings of the abdomen and trigger cancerous cells to develop in the mesothelium. Mesothelioma can take anywhere between 15 and 60 years to develop after exposure to asbestos.
Other risk factors include genetics, smoking and aging. People in their 40s and 50s are more likely to get mesothelioma than people younger or older. It takes mesothelioma 20-60 years to show signs of cancer after the first exposure. It is important to remember, too, that mesothelioma may occur in those who have been exposed to asbestos without having directly worked with it. This is known as secondary or indirect asbestos exposure. It can be as hazardous as direct asbestos exposure.
asbestos lawyer of mesothelioma because it damages the mesothelium. It can also make it more vulnerable. Additionally, mesothelioma can be worsened by certain diseases like pneumonia and asbestosis. Men are more likely to develop mesothelioma compared to women. This is because men are more likely to work with asbestos and experience a more exposure than women. Also, men are more likely to live with someone who worked with asbestos and carry stray asbestos fibers home on their clothing. Women tend to have less contact with asbestos and rarely carry asbestos home on their clothing.
Diagnosis
It is difficult to diagnose mesothelioma because its symptoms are frequently similar to other illnesses. Due to this, patients are often misdiagnosed.
NYU Langone doctors will perform an examination of the body and document the patient's medical background, including asbestos exposure. Doctors will also recommend a CT scan or chest X-ray to look for lumps, abnormalities and evidence of asbestos exposure. These include plaques in the pleura, thickened pleura and calcium deposits.
Other diagnostic tests include a magnetic resonance scan, or MRI test, which makes use of radio waves and magnets to create a series detailed images of the inside of the body. A surgical biopsy is another method doctors use to diagnose mesothelioma. A surgical biopsy is when doctors remove a small amount of tissue from the pleura or peritoneum for further analysis. A pathologist will then look at the tissue using a magnifying lens to determine whether it contains cancerous cells.
Mesothelioma is classified based on the type of mesothelial cell involved, whether the cells are malignant or benign and also the location of the tumor, its type, and the stage of the tumor. Certain mesothelioma types have a higher risk of spreading or metastasizing therefore it is essential to determine the type of mesothelioma so doctors can treat it prior to it becoming out-of-control.
Doctors can also run tests in the laboratory on a tumor to find specific proteins, genes and other factors which can help them identify the characteristics of the cancer and determine a treatment. These results are referred to as staging.
Treatment
A mesothelioma diagnose can be frightening. However, it is important to remember that the disease is treatable, particularly in its early stages. Many patients with mesothelioma survive for years with the disease without it spreading to other areas of their body.
Exposure to asbestos may cause mesothelioma through a variety of ways. Asbestos fibers, too small to see or feel with the naked eye, can become airborne and irritate the lung's lining (pleura). Over time irritation leads to formation of scar tissue which leads to changes in the structure of cells that eventually develop into tumors.
The pleura is a protective covering that surrounds the abdomen, heart, and lungs. Mesothelium consists of cells that react to exposure to asbestos, causing it to inflame and create scar tissue. These changes eventually result in malignant mesothelioma tumors.
Breathing problems, chest discomfort, or the accumulation of fluid on the lungs are all indications of pleural mesothelioma. In rare instances cancer may spread to the tissues surrounding the reproductive organs as well as the heart.
If imaging scans reveal a possible mass in the lungs or stomach, a doctor will order biopsies. During the procedure, doctors will remove small amounts of the fluid or tumor for lab analysis. The results can confirm the diagnosis of mesothelioma, and also determine the best treatment option.
There are many types of mesothelioma treatments, including surgery, chemotherapy and immunotherapy. Most doctors utilize combinations of these treatments. Patients may also benefit from taking part in a clinical trial of new mesothelioma treatments. To learn more about the trials, patients should speak with mesothelioma experts who have expertise in treating the condition.
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