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Recognition involving Thirty eight Heterogeneous Drug Prospects for Treatment of COVID-19 with a Rational Transcriptomics-Based Drug Repurposing Strategy.
HEMS EFAST has the potential to triage certain trauma patients directly to the operating room or newly emerging hybrid suites, bypassing the emergency room and saving crucial time.
Prehospital guidelines state that monitoring should match in-hospital standards, but consensus on the use of arterial blood gases (ABGs) and arterial lines remains unclear. The aim was to perform a systematic literature review and survey of UK helicopter emergency medical services (HEMS) use and perceptions of ABGs and arterial lines.

A systematic literature review was conducted for arterial lines and ABGs and prehospital care. Additionally, two questionnaires were distributed to all UK HEMS (questionnaire 1 current clinical practice and questionnaire 2 clinicians' opinions).

From 1,028 results, 13 studies (10 ABGs and 3 arterial lines) were included, demonstrating it is feasible to obtain ABGs and place arterial lines in the prehospital setting. There were concerns about practical difficulties for ABGs and the time taken for arterial lines. Survey responses were obtained from all UK HEMS (N=22). Six services carry equipment for performing ABGs and nine services for arterial lines. Clinicians expressed concerns relating to the time taken to perform both procedures, but most believed it would allow better monitoring and more targeted treatment.

The evidence of benefit for both procedures remains poor. Overall, there may be clinical benefits, but these are likely to be patient specific and require further investigation.
The evidence of benefit for both procedures remains poor. Overall, there may be clinical benefits, but these are likely to be patient specific and require further investigation.
Tranexamic acid (TXA) has demonstrated a reduction in all-cause mortality in trauma patients with hemorrhage. Administering TXA in the prehospital setting presents unique challenges because the identification of bleeding is based on clinical suspicion without advanced imaging or diagnostic tools. The objective of this study was to examine whether prehospital suspicion of bleeding is validated by in-hospital computed tomographic imaging and examination and to determine if patients received TXA in the absence of hemorrhage. The study was conducted at a level 1 trauma center supported by air medical transport services.

This is a retrospective cohort study examining 88 trauma patients receiving prehospital TXA to treat suspected hemorrhage. Adult trauma patients who received TXA during the study period and were transported to our level 1 trauma center were included. A panel of trauma surgeons reviewed CT imaging and examination findings to retrospectively identify significant hemorrhage.

Forty-three percent of patients who received TXA during air medical transport did not have confirmed hemorrhage upon arrival.

TXA was given to a significant number of patients who did not have confirmed hemorrhage upon arrival. We recommend that institutions using TXA perform this internal validation to ensure they are accurately identifying hemorrhage in the prehospital setting.
TXA was given to a significant number of patients who did not have confirmed hemorrhage upon arrival. We recommend that institutions using TXA perform this internal validation to ensure they are accurately identifying hemorrhage in the prehospital setting.
The aim of this study was to investigate, describe, and analyze the Norte Novo regional air medical service provided by the Brazilian Emergency Medical Rescue Service.

This was a retrospective and descriptive study with a quantitative approach of the incidents registered from November 2016 to December 2019. For general patient classification, descriptive statistics of the following variables were performed sex, age/age group, type of diagnosis, city where the incident took place, city of destination, length of patient care, ventilatory support, use of sedation, and use of vasoactive drugs. All analyses were performed using the XLSTAT program (Version 19.4; Addinsoft, New York, NY), considering a significance level of 5%.

There were 1,677 responses divided into clinical (60.8%), traumatic (37.8%), organ transport (1.2%), and interhospital transference (0.2%). The most frequent diagnoses were acute myocardial infarction and stroke (clinical care) and polytrauma (trauma care). The average waiting time until the helicopter arrived at the scene was 25 minutes.

This study shows the importance and relevance of this air medical service for the area it covers. Further research is needed to address the profile of this service in our country, which will allow us to elucidate scenarios and develop strategies to assist the population and, thus, design training and simulation exercises for emergency service teams based on local realities.
This study shows the importance and relevance of this air medical service for the area it covers. Further research is needed to address the profile of this service in our country, which will allow us to elucidate scenarios and develop strategies to assist the population and, thus, design training and simulation exercises for emergency service teams based on local realities.Registered nurses are core members of critical care ground transport teams because of their education, experience, and scope of practice. Advances in medicine, technology, and equipment, combined with regionalization of specialized care and, most recently, the coronavirus disease 2019 pandemic, necessitate that transport nurses possess specialized knowledge, skills, and abilities. National specialty certification in ground transport nursing via the Certified Transport Registered Nurse (CTRN) offers registered nurses a process to validate their expertise. The most recent transport nursing role delineation study, which was conducted by the Board of Certification for Emergency Nursingin 2019, provided the foundation for the revised CTRN examination content outline, which is now separate from the Certified Flight Registered Nurse (CFRN) content outline. In this article, we provide a brief history of the specialty of ground transport nursing; details on the CTRN examination blueprint; and a composite patient case report to illustrate the ground-specific role, expertise, and contributions of the CTRN in delivering the highest level of patient care during ground transport.
Non-communicable diseases (NCDs) are responsible for 74% of global deaths and contributed to significant disabilities, worsening health-related quality of life (HRQoL). In NCDs, poor medication adherence, social support, patient-physician relationship, and health literacy decrease HRQoL. Unfortunately, there is a shortage of literature examining the predictors of HRQoL among patients with different types of NCDs.

This study aimed to examine the predictors of Health-Related Quality of Life (HRQoL), including health literacy, social support, patient-physician relationship, and medication adherence, among patients with NCDs.

This national cross-sectional study used a correlational design and included 800 Omani participants with six NCDs. Self-reported questionnaires were used to measure HRQoL, health literacy, patient-physician relationship, social support, and medication adherence. Multiple linear regression analysis was used to examine predictors of HRQoL.

Participants' mean age was 56years (SD=15.60).luencing physical functioning, social functioning, role functioning, and mental health dimensions of HRQoL among patients with NCDs.
This study constructed and tested a structural equation model on clinical nurses' emotional labor, job satisfaction, and job performance based on Grandey's emotion regulation model.

We performed a correlational study to predict the relationship between the following variables emotional labor (surface and deep acting), job satisfaction, job performance, self-efficacy, emotional intelligence, display rules, job autonomy, social support, and job stress.

Our hypothetical model was based on Grandey's emotional regulation model and on a literature review of emotional labor, job satisfaction, and job performance. Structured questionnaires were distributed to participants who worked in seven general hospitals with no less than 300 beds in a province, South Korea. We analyzed 424 questionnaires and used AMOS 23 to explore the relationships between the constructs.

Our model fit the data well (χ
=96.420, GFI=0.966, CFI=0.956, RMSEA=0.084). Display rules, self-efficacy, job autonomy, and job stress accounted forl can help hospital management to adjust their customer service guidelines to improve nurses' job satisfaction and performance.
This study filled the need for an integrated structural equation model of emotional labor. With this model, we found that emotional labor operates differently in nursing practice than in other service fields. As such, this model can help hospital management to adjust their customer service guidelines to improve nurses' job satisfaction and performance.Researchers and clinical nurses need to collaborate to develop the clinical setting. Negotiating access to do research in the clinical setting can be challenging. The task of gaining access is often omitted and scarcely described in the literature. The aim of this article is to describe a process to gain access based on the authors' individual and collective experience through reflective conversations. The process consists of four key components researcher, review board, gatekeepers and participants. Each component is linked and a crucial step to gain access to the clinical setting and ultimately to the participants. The gaining access process may prepare novice researchers for the specific considerations, time and effort required to initiate research in the clinical setting.
Patients are restricted to bed and required to lie flat after coronary angiography (CAG) due to potential risk of vascular complications. This often causes back pain.

We aimed to investigate the effect of the head of bed (HOB) elevation on back pain and vascular complications after elective CAG.

Three hundred and seven consecutive patients who underwent elective CAG were randomized into three groups. One control (HOB 0 degree-flat position) and two experimental (HOB 15 and 30 degrees) groups were compared. Back pain level was assessed using a visual analog scale.

Mean age was 58.1±10.7, and 59.9% (n=184) of the patients were males. Pain level at the 3rd hour and at the 6th hour was significantly higher in the control group than in the experimental groups. In the post-hoc analysis, pain level was significantly higher in HOB 15 degrees compared to that in HOB 30 degrees. In the multivariate analysis, HOB elevation to 30 degree was the only independent predictor of the pain level at the 3rd hour and the 6th hour. Only one patient in the HOB 0 degree group had a minor bleeding at the access site CONCLUSIONS Elevation of the HOB to 30 degrees was associated with decreased back pain level without increased risk of vascular complications.
Mean age was 58.1±10.7, and 59.9% (n=184) of the patients were males. Pain level at the 3rd hour and at the 6th hour was significantly higher in the control group than in the experimental groups. In the post-hoc analysis, pain level was significantly higher in HOB 15 degrees compared to that in HOB 30 degrees. In the multivariate analysis, HOB elevation to 30 degree was the only independent predictor of the pain level at the 3rd hour and the 6th hour. Only one patient in the HOB 0 degree group had a minor bleeding at the access site CONCLUSIONS Elevation of the HOB to 30 degrees was associated with decreased back pain level without increased risk of vascular complications.
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