Notes

Ageing Post-Seismic Deformation Noticed about the Mandarin chinese Peninsula Following a The new year Tohoku-Oki Earth quake.
Overall, this study demonstrated the significance of spatial structure of street network around the homes in the potential for encouraging AST, and more importantly, the need to consider objective and perceived environmental attributes when strategizing means to increase this mode choice and reduce ill-health among children.Pollutant gases, such as CO, NO2, O3, and SO2 affect human health, and low-cost sensors are an important complement to regulatory-grade instruments in pollutant monitoring. Previous studies focused on one or several species, while comprehensive assessments of multiple sensors remain limited. We conducted a 12-month field evaluation of four Alphasense sensors in Beijing and used single linear regression (SLR), multiple linear regression (MLR), random forest regressor (RFR), and neural network (long short-term memory (LSTM)) methods to calibrate and validate the measurements with nearby reference measurements from national monitoring stations. For performances, CO > O3 > NO2 > SO2 for the coefficient of determination (R2) and root mean square error (RMSE). check details The MLR did not increase the R2 after considering the temperature and relative humidity influences compared with the SLR (with R2 remaining at approximately 0.6 for O3 and 0.4 for NO2). However, the RFR and LSTM models significantly increased the O3, NO2, and SO2 performances, with the R2 increasing from 0.3-0.5 to >0.7 for O3 and NO2, and the RMSE decreasing from 20.4 to 13.2 ppb for NO2. For the SLR, there were relatively larger biases, while the LSTMs maintained a close mean relative bias of approximately zero (e.g., less then 5% for O3 and NO2), indicating that these sensors combined with the LSTMs are suitable for hot spot detection. We highlight that the performance of LSTM is better than that of random forest and linear methods. This study assessed four electrochemical air quality sensors and different calibration models, and the methodology and results can benefit assessments of other low-cost sensors.Application of glass- or carbon-fiber-reinforced polymer (GFRP/CFRP) bars makes the direct use of seawater and sea sand concrete (SWSSC) in construction feasible, which is of high interest in order to conserve the limited resources of fresh water and river sand. The present paper performed the life cycle assessment (LCA) of constructing three kinds of beams (GFRP/CFRP bar-reinforced SWSSC beams, and steel bar-reinforced common concrete (SRC) beam) in marine environments to show the environmental benefits of using FRP bar-reinforced SWSSC beams in marine environments. According to ISO 14040 and ISO 14044, stages including production, transportation, construction, use and end-of-life are within the LCA's boundary. The ReCiPe method and eight main environmental impact categories were used to characterize the environmental impacts of those beams. LCA results indicate that one cubic meter SWSSC possesses much lower environmental impacts in terms of all eight categories compared with common concrete with the same volume when used in marine environments, with reduction rates from 26.3% to 48.6%. When the two transportation distances were set as 50 and 20 km and without considering the difference in service life, compared to SRC beam, GFRP-SWSSC beam performs better in six categories and CFRP-SWSSC beam performs better in four categories. When considering increased transportation distance and the higher durability performance, the advantageous categories for GFRP-SWSSC and CFRP-SWSSC beams increase to seven and six, respectively. The environmental impacts of all the three beams are mainly affected by the production stages.
Cardiac manifestation of COVID-19 has been reported during the COVID pandemic. The role of cardiac arrhythmias in COVID-19 is insufficiently understood. This study assesses the incidence of cardiac arrhythmias and their prognostic implications in hospitalized COVID-19-patients.

A total of 166 patients from eight centers who were hospitalized for COVID-19 from 03/2020-06/2020 were included. Medical records were systematically analyzed for baseline characteristics, biomarkers, cardiac arrhythmias and clinical outcome parameters related to the index hospitalization. Predisposing risk factors for arrhythmias were identified. Furthermore, the influence of arrhythmia on the course of disease and related outcomes was assessed using univariate and multiple regression analyses.

Arrhythmias were detected in 20.5% of patients. Atrial fibrillation was the most common arrhythmia. Age and cardiovascular disease were predictors for new-onset arrhythmia. Arrhythmia was associated with a pronounced increase in cardiac bion. Whereas in-hospital mortality is affected by underlying cardiovascular conditions, arrhythmia during hospitalization for COVID-19 is independently associated with prolonged hospitalization and mechanical ventilation. Thus, incident arrhythmia may indicate a patient subgroup at risk for a severe course of disease.When a brittle thin rod, such as a dry spaghetti stick, is bent beyond its flexural limit, it often breaks into more than two pieces, typically three or more. This phenomenon and puzzle has aroused widespread interest and discussion since its first proposal by Feynman. Previous work has partly explained the inevitability of the secondary fracture, but without any adjustable time parameter. In order to further understand this problem, especially the secondary fracture, in this paper we propose and study the dynamics of a half-infinite model to mimic the physics that a spaghetti stick is half-infinite under uniform bending. When the breaking process starts, a gradual release of initial moment of a linearly declining time at the free end, instead of a sudden release, is adopted, resulting in the introduction of a characteristic time parameter to the model and agrees better with the real situation. A specific analytical solution in terms of the excited bending moment using Euler-Bernoulli beam theory is derived, and that the gradual release of initial moment induces a burst of flexural waves, and these flexural waves locally increase the moment in the stick and progressively get to the maximum value, and then lead to the secondary fracture are concluded. The excited moment increases with time and distance, and has an asymptotic extremum value of 1.43 times initial moment. The gradual release in our model requires and gives certain distance and time when the excited bending moment reaches its extremum value, which provides a possibility to predict the detailed fracture parameters such as fragmentation length and time and thus to further understand the secondary fracture during spaghetti bent break.Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay is a long-established assay used to detect cell death-associated DNA fragmentation (3'-OH DNA termini) by endonucleases. Because these enzymes are particularly active in the kidney, TUNEL is widely used to identify and quantify DNA fragmentation and cell death in cultured kidney cells and animal and human kidneys resulting from toxic or hypoxic injury. The early characterization of TUNEL as an apoptotic assay has led to numerous misinterpretations of the mechanisms of kidney cell injury. Nevertheless, TUNEL is becoming increasingly popular for kidney injury assessment because it can be used universally in cultured and tissue cells and for all mechanisms of cell death. Furthermore, it is sensitive, accurate, quantitative, easily linked to particular cells or tissue compartments, and can be combined with immunohistochemistry to allow reliable identification of cell types or likely mechanisms of cell death. Traditionally, TUNEL analysis has been limited to the presence or absence of a TUNEL signal. However, additional information on the mechanism of cell death can be obtained from the analysis of TUNEL patterns.Conventional methods employed today for the synthesis of amides often lack of economic and environmental sustainability. Triazine-derived quaternary ammonium salts, e.g., 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM(Cl)), emerged as promising dehydro-condensation agents for amide synthesis, although suffering of limited stability and high costs. In the present work, a simple protocol for the synthesis of amides mediated by 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and a tert-amine has been described and data are compared to DMTMM(Cl) and other CDMT-derived quaternary ammonium salts (DMT-Ams(X), X Cl- or ClO4-). Different tert-amines (Ams) were tested for the synthesis of various DMT-Ams(Cl), but only DMTMM(Cl) could be isolated and employed for dehydro-condensation reactions, while all CDMT/tert-amine systems tested were efficient as dehydro-condensation agents. Interestingly, in best reaction conditions, CDMT and 1,4-dimethylpiperazine gave N-phenethyl benzamide in 93% yield in 15 min, with up to half the amount of tert-amine consumption. The efficiency of CDMT/tert-amine was further compared to more stable triazine quaternary ammonium salts having a perchlorate counter anion (DMT-Ams(ClO4)). Overall CDMT/tert-amine systems appear to be a viable and more economical alternative to most dehydro-condensation agents employed today.This paper focuses on the investigation of the diagnostic system for health monitoring and defects, detecting in composite structures using a piezoelectric sensor. A major overview of structural defects in composite materials that have an influence on product performance as well as material strength is presented. Particularly, the proposed diagnostic (health monitoring) system enables to monitor the composite material plate defects during the exploitation in real-time. The investigated health monitoring system can indicate the material structure defects when the periodic test input signal is provided to excite the plate. Especially, the diagnostic system is useful when the defect placement is hard to be identified. In this work, several various numerical and experimental studies were carried out. Particularly, during the first study, the piezoelectric transducer was used to produce mechanical excitation to the composite plate when the impact response is measured with another piezoelectric sensor. The second study focuses on the defect identification algorithms of the raw hologram data consisting of the recorded oscillation modes of the affected composite plate. The main paper results obtained in both studies enable us to determine whether the composite material is characterized by mechanical defects occurring during the response to the periodic excitation. In case of damage, the observed response amplitude was decreased by 70%. Finally, using the time-domain experimental results, the frequency response functions (FRFs) are applied to damage detection assessment and to obtain extra damage information.Aim to report clinical outcome in patients with acinic cell carcinoma of the salivary glands treated with intensity-modulated radiotherapy (IMRT) and carbon ion radiotherapy (CIRT) boost. Materials and Methods all patients with acinic cell carcinoma of the salivary glands treated at the Heidelberg Ion-Beam Therapy Center were considered for this retrospective analysis. All patients received a CIRT boost with 18-24 Gy radiobiologic effectiveness (RBE)-weighted dose in 3 Gy RBE-weighted dose per fraction followed by IMRT, with 50-54 Gy in 2 Gy per fraction. Disease outcome was evaluated for local (LR), nodal (NR), distant recurrence (DR), and disease-free (DFS) and overall survival (OS). Morbidity was scored based on Common Terminology Criteria for Adverse Events (CTCAE) version 5. Descriptive statistics and the Kaplan-Meier method were used for analysis. Results fifteen patients were available for analysis. Median follow-up after radiotherapy was 43 months. Six patients were treated for primary disease and nine for recurrent disease.
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