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Isolated Kidney Mucormycosis in Children: An incident Document along with Review of your Books.
In the experimental model of osmotic BBB disruption, the elevation of ICP started earlier but was of very short duration. In WI model the elevation of ICP was present during the whole period of monitoring. CONCLUSION Our results indicate that purely experimental models of brain edema (WI, BBBd) without any parallel pathological process can compromise the basic brain homeostatic activity.BACKGROUND Two-dimensional speckle-tracking echocardiography (2D STE) has been demonstrated to have certain diagnostic utility in heart transplantation (HTX) patients with acute cardiac allograft rejection (ACAR). The aim of the systematic review and meta-analysis was to evaluate the diagnostic value of common strain parameters for ACAR in HTX patients. METHODS After conducting a database search, we selected studies evaluating left ventricular global longitudinal strain (GLS), circumferential strain (CS), radial strain (RS), and free wall right ventricular longitudinal strain (RV FW) in rejection group vs rejection-free group. RESULTS After reviewing 886 publications, seven studies were finally included in the meta-analysis, representing the data of 1173 pairs of endomyocardial biopsy and echocardiographic examination. click here Heart transplantation patients with rejection had significantly lower GLS than rejection-free subjects (weighted mean difference -2.32 (95% CI, -3.41 to -1.23; P less then .001). Heart transplantation patients with rejection had significantly lower CS than rejection-free subjects (weighted mean difference -2.49 (95% CI, -4.05 to -0.91; P = .0019). link2 In addition, HTX patients with rejection also had significantly lower RV FW (weighted mean difference -4.90 (95% CI, -6.15 to -3.65; P less then .001). CONCLUSIONS The meta-analysis and systematic review demonstrate that myocardial strain parameters derived from 2D STE may be useful in detecting ACAR in HTX patients. The present results provide encouraging evidence to consider the routine use of GLS, CS, and RV FW as markers of graft function involvement during ACAR. © 2020 Wiley Periodicals, Inc.The feeding trial was conducted to investigate the effect of Azolla spp. inclusion in feed ingredient of broiler chickens. Two hundred of day-old broiler chicks were raised in Farm 15, Faculty of Agriculture, Universiti Putra Malaysia. The birds were individually wing banded, weighed and allocated into four treatment groups (control 0% of Azolla spp., T1 5% of Azolla spp., T2 10% of Azolla spp. and T3 15% of Azolla spp.). Each group has five replicates and ten birds per pen. All the birds were fed ad libitum during the feeding trial, which lasted 42 days. During the end of the starter and finisher phase, two birds from each replicate were slaughtered. link3 Ileal digesta sample was collected to determine the nutrient digestibility of the Azolla spp. on broiler chickens. Azolla spp. nutritional content was 5.14% dry matter, 24.82% crude protein, 16.64% crude fibre, 2.00% ether extract, 11.59% ash, 34.95% nitrogen-free extract, 42.52% neutral detergent fibre, 31.15% acid detergent fibre, 16.86% acid detergent lignin, 11.37% hemicellulose and 14.29% cellulose. The result from this study showed T3 (15% of Azolla spp.) has significantly highest (p .05) among treatments. For the nutrient digestibility experiment, the findings showed compared with a control group, feeding of 10% or 15% of Azolla spp. led to significant improvement (p less then .05) in nutrient digestibility. The studies conclude the inclusion of Azolla spp. up to 15% in broiler chicken feed ration can improved growth of body performance and showed no adverse effect on the growth performance and nutrient digestibility of the birds. © 2020 Blackwell Verlag GmbH.A 26-year-old man, with human immunodeficiency virus infection, on hemodialysis, was hospitalized due to infective endocarditis. A mechanical prosthetic mitral valve was implanted. During postoperative period, he maintained signs suggestive of infection. The transthoracic echocardiograms (TTE) revealed a pericardial effusion. One week later was visible a circumscribed collection compatible with a pericardial abscess. He was refused for cardiac surgery; however, inflammatory parameters elevation persisted. The TTE showed a periprosthetic mitral leak, and cardiac surgery was performed. The pericardial drainage revealed a hematoma. This case highlights the difficulty on echocardiographic differential diagnosis between a pericardial hematoma and pericardial abscess in clinical practice. © 2020 Wiley Periodicals, Inc.BACKGROUND Increased plasma concentration of N-terminal-prohormone B-type natriuretic peptide (NT-proBNP) can be detected in cats with cardiac disease. Potential effects of feline characteristics on NT-proBNP concentration may influence clinical usefulness. OBJECTIVES To evaluate potential effects of feline characteristics on NT-proBNP plasma concentration and to compare NT-proBNP plasma concentrations in healthy cats with results in hypertrophic cardiomyopathy (HCM) cats with or without left atrial enlargement (LAE) using an ELISA and a point-of-care test (POCT), and assess if POCT results reflect ELISA results. ANIMALS One hundred healthy cats of 3 breeds and 39 HCM cats were included. METHODS Diseases other than HCM were excluded by physical examination, blood pressure measurement, echocardiography, hematology, and serum biochemistry. RESULTS Higher NT-proBNP concentrations were found in males than in females in healthy (P = .005) and in HCM cats (P = .0021), but breed had no effect on NT-proBNP concentrations. Using ≥100 pmol/L as a cutoff for abnormal samples, ELISA and POCT had similar sensitivity (SE; 72 and 74%) and specificity (SP; 97 and 98%) for detecting cats with HCM, cats with HCM and LAE (SE, both 100%; SP, 97 versus 98%), and cats with HCM without LAE (SE, both 69%; SP, 97 versus 98%), respectively, when compared to healthy cats. CONCLUSIONS AND CLINICAL IMPORTANCE Breed had no effect on plasma NT-proBNP concentrations, but higher concentrations were found in male than in female cats. The ELISA and POCT had similar SE and SP for detecting HCM. Both tests could identify all HCM cats with LAE but not all HCM cats without LAE. © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.This report describes the case of a 13-day-old African American female with persistent hypoxia found to have an isolated right superior vena cava (RSVC) draining into the left atrium (LA) confirmed with contrast echocardiography. © 2020 Wiley Periodicals, Inc.According to national hospice data in Hungary, approximately 1,600 healthcare employees and volunteers work in hospice care (country population of 9.9 million). The aim of the study was to identify and examine influential relationships among several variables that may affect well-being among female hospice workers. Structural equation modeling analysis was conducted utilising survey responses of 179 female hospice workers, including 79 nurses. Path analysis revealed that work over-commitment (being employed in more than one job) contributed to decreased psychological well-being through increased perceived stress, sleep difficulties and vital exhaustion. A greater sense of coherence was associated with lower levels of subjective stress, depressive symptoms and vital exhaustion and negatively correlated with over-commitment. Overall, even though the physical and mental burden of the workers is increasing because of increased use of hospice, according to these results, most still engaged in hospice work. Deeper analysis of the sense of coherence may point to development of effective interventions that can help maintain well-being of hospice workers and reduce attrition. © 2020 John Wiley & Sons Ltd.BACKGROUND The Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical myxomatous mitral valve disease (EPIC) study monitored dogs with myxomatous mitral valve disease (MMVD) as they developed congestive heart failure (CHF). OBJECTIVES To describe the changes in clinical and radiographic variables occurring as dogs with MMVD and cardiomegaly develop CHF, compared to similar dogs that do not develop CHF. ANIMALS One hundred and thirty-five, and 73 dogs that did or did not develop CHF, respectively. MATERIALS AND METHODS The following variables were evaluated in 2 groups of dogs (dogs that did or did not develop CHF) Heart rate (HR), clinic respiratory rate (RR), home-measured resting respiratory rate (RRR), rectal temperature (RT), body weight (BW), and vertebral heart sum (VHS). Absolute value and rate of change of each variable were calculated for each day a dog was in study. Daily means were calculated and plotted against time. The onset of CHF or last visit before leaving the study were set as reference time points. RESULTS The most extreme values and rate of change occurred in variables immediately before onset of CHF. Vertebral heart sum increased earliest. Heart rate, RR, and RRR also increased. Rectal temperature and BW decreased. Increases in RR and RRR were most extreme and occurred immediately before CHF. CONCLUSIONS AND CLINICAL IMPORTANCE Dogs with MMVD and cardiomegaly experience increases in HR, RR, RRR, and VHS, and decreases in BW and RT as they develop CHF. The variables with highest absolute change and rate of change were RR and RRR. These findings reinforce the value of RR and RRR as indicators of impending or incipient CHF. © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.As diverse racial and ethnic minority populations continue to grow in the United States, the racial and ethnic diversity of the genetics workforce has remained virtually unchanged over the past 50 years. This is especially true in the genetic counseling profession where 90% of genetic counselors in the most recent Professional Status Survey reported as White. In order to improve access to genetic services and education for minority families, it is important to increase the availability of minority genetic healthcare providers. The Health Resources and Services Administration funded Western States Regional Genetics Network has created a Minority Genetic Professionals Network (MGPN) to recruit and mentor high school and undergraduate students to enter genetic professions such as genetic counseling. The MGPN has also expanded to provide support, education, and mentor matching for current practicing genetic counselors and genetic counseling students. This Network is an initial step towards developing a more diverse genetics workforce to meet the needs of diverse families in the United States. © 2020 National Society of Genetic Counselors.OBJECTIVE Pulmonary hypertension (PH) and ischemic digital lesions (DL) are two scleroderma vascular outcomes that in cross-sectional studies are associated with abnormalities in biomarkers of angiogenesis. The clinical usefulness of these biomarkers is unknown in part due to lack of data on longitudinal measurement. METHODS We conducted a prospective cohort study of 300 patients with systemic sclerosis (SSc) who were followed for at least a five-year period, who at enrollment lacked evidence of PH and/or active DL. Levels of hepatocyte growth factor (HGF), soluble Flt-1, soluble endoglin, endostatin, and platelet-derived growth factor (PlGF) were obtained at multiple time points and assessed for their ability to predict the development of PH/DL. RESULTS 46 patients (15%) developed PH and 69 (23%) developed a DL. In time-to-event analyses, three biomarkers measured at cohort entry were found to significantly associate with the development of PH HGF (HR 1.99, 95%CI 1.24-3.17, p=0.004), sFlt1 (HR 3.04, 95%CI 1.
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