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Synuclein Family Reduce Tissue layer Injury by simply Counteracting α-Synuclein Gathering or amassing.
Whilst, median of TSH in replete area was 1.27 (0.09-8.21) ng/dL and non replete area was 1.3 (0.01-8.67) ng/dL. Correlation between fT4 and TSH showed significat relationship in non-replete area, r=-0.39 (0.05). In addition, scatter plot showed the relationship between fT4 and TSH levels pattern in the replete area more widespread. Pregnant womens who live in areas that had affected severe iodine deficiency intake may have abnormal thyroid function but it still euthyroid maintain by adequate iodine intake.Elderly is defined as an age group that is susceptible to various diseases. The aging process in the elderly is associated with an increase in oxidative stress activity which can lead to various health problems which are a major cause of high mortality and morbidity. selleck products This study aimed to analyze the effect of supplementation of catfish (Clarias gariepinus) oil enriched with omega-3 soft capsule on oxidative stress and cognitive function of elderly people. The design of this study was a single blind randomized control trial. A total of 29 elderly subjects were chosen following these inclusion criteria aged >60 y; had dyslipidemia; and signed the informed consent. Subject were divided into three groups i.e. SO (soybean oil), CFO (commercial fish oil), and CO with omega-3 (catfish oil enriched with omega-3). The intervention was 1,000 mg oil/d administered for 90 d. The results showed that different supplementation groups had significant effects on oxidative stress and cognitive function (p less then 0.05). Supplementation of catfish oil enriched with omega-3 was able to significantly decreased malondialdehyde (MDA) level (p less then 0.05) and significantly increased mini mental state examination (MMSE) score (p less then 0.05). Overall, CO with omega-3 supplementation for 90 d was able to improve oxidative stress and cognitive function of the elderly better than other groups.Iodine deficiency affects people of all age groups and yields detrimental health effects known as Iodine Deficiency Disorders (IDD). Universal Salt Iodization (USI) where above 90% household use iodized salt became the main program to optimized population iodine status. This study aimed to analyze iodine in salt, iodine status and thyroid functions from three different IDD endemic regions.
This was a cross-sectional study, with women of reproductive age (15 to 45 y old) as subjects, conducted in plain area (Yogyakarta) city (n=250), mountainous area (Bukit Tinggi city) (n=249), and combination of mountaneous and plain area (Purworejo regency) (n=249). Urinary iodine (UIE), prevalence of hyperthyroidism, and hypothyroidism (diagnostic based on combination of TSH and fT4 level), also the presence or absence and level of iodine in salt were assessed.

Iodized salt coverage have reached >90% household in all three region, while titration found 75.6% with adequate level of iodine in salt (>30 ppm), with wichieved USI target. But the risk of iodine deficiency still found in mountaneous area. Household iodized salt coverage discrepancy between rapid test and titration strengthen the need of more accurate but efficient test of iodine level in salt.Anemia and iron deficiency can cause detrimental effects on brain development, and continued iron deficiency anemia is known to interfere with development which results in a permanent delay in mental and Motor development. This study investigated the impact of anemia on physical development skills of under two years children in aceh besar district. A cross-sectional study design was applied to 102 under-two years children selected using cluster random sampling technique using village as cluster. A structured questionnaire to determine general characteristics such as maternal age, maternal education, maternal occupational, family income, number of family members and toddlers. Anemia status was assessed by Hemocue 201+ tool, and physical motor development such as gross and fine motor development skills were determined using Denver II instrument. Almost two- thirds of children were anemia, as assessed by blood hemoglobin levels of less then 11 g/dL, while 34.3% of them were experienced delay in either fine development or gross development skills. The prevalence of children with fine and gross motor development delay was higher in children with suffering from anemia (27.1% and 17.1%) than non-anemia, respectively (3.2% and 9.4%). There was significant association anemia status on fine motor development (r=0.291; p=0.003), while not significant to gross motor development (r=0.092; p=0.357). The prevalence of anemia in children 12-24 mo old was very high, and has an impact on motor development delays, so anemia prevention programs and motor stimulation intervention for under two years children are needed.Several minerals are needed for thyroid hormone to work properly, such as iodine and iron. Iron is one of important essential trace elements that serves as co-factor for thyroid peroxidase (TPO). Those with iron deficiency have lower ferritin serum level than those who are normal. In particular, pregnant women with chronic energy deficiency (CED) have higher anemia risk than the otherwise. The study aimed to measure ferritin level, CED and hypothyroidism among pregnant women living in iodine deficiency disorders (IDD) endemic areas. A total of 37 pregnant women aged 18-45 y-oldwith pregnancy of 2 to 8 mo living in ID Dendemic of Dayakan and Watu Bonang Villages of Ponorogo District were include dinthestudy. Two different measurements were taken namely, anthropometric measurement of mid-upper arm circumference (MUAC) or upper circumference (UAC) which is more correct term to use, and blood markers of iodine and iron status were assessed using thyroid stimulating hormone (TSH), free thyroxine (fT4), and bloodferritin. Among pregnant women, 27% had hypothyroidism and 54.05% had iron depletion, with 30% had both conditions. The hypothyroidism was higher in pregnant women had CED than those non-CED, 50% vs. 18.5%. No significant correlation (p≥0.05) between hypothyroidism and both ferritin and CED, but adjusted odds ratio (AOR) was found at 7.7 (95% CI 1.2-52.9), indicated more than four times higher risk of hypothyroidism in pregnant women with CED than the otherwise. Hypothyroidism in pregnant women living in Ponorogo was not caused by iron deficiency, but allegedly by lack of other nutritional intake. Conclusion Integrated and sustainable efforts to improve nutritional status is needed since pre-conception and throughout pregnancy.It is well-established that school feeding program (SFP) has been provided significant nutritional and health beneficial effects to student namely. SFP or school meal services program without nutritionist have lack of food delivery system, nutrient quality and health promotion. Thus, the aim of this study was to analyze the influence of nutritionist-based food service delivery system on food and nutrient quality of school lunch program in primary school.
This study used cross-sectional design in two primary school in Indonesia that use different models of SFP (on-site (public-owned-public-managed) kitchen, off-site (ready-to-eat foods will be taken to school, preparation, cooking and sprinkling processes are carried out outside the school (catering)). Comparison analysis was done by using t-test independent.

We found that food service on-site model with nutritionist (Al Muslim) in school meal service, menu quality and hygiene sanitation better than Al Hidayah primary school (catering without nutritionist). The adequacy of nutrients particularly protein, calcium and iron in Al Hidayah students was significantly different than Al Muslim student (p-value<0.05).

Primary school need to collaborate with nutritionist to plan the menu and food service system to achieve optimal nutritional status.
Primary school need to collaborate with nutritionist to plan the menu and food service system to achieve optimal nutritional status.Poor nutritional status or stunting still becomes a public health problem in Indonesia, with prevalence of 37.2% in 2013. Some research results show that stunted children have lower cognitive development than normal children. This study aims to assess whether there is an effect of giving multiple-nutrient biscuits and psychosocial parenting education on height and development of children under the age of three (toddlers). This study used quasi experimental design. The treatment was given for 2 mo to 28 stunted children who were divided into 3 groups, namely (1) multiple-nutrient biscuits (2) psychosocial parenting education (3) multiple-nutrient biscuits and psychosocial parenting education. Multiple-nutrients biscuit was given 12 pieces a day for 2 mo. Meanwhile, psychosocial parenting education was given direcly by psychologist in the form of lectures, brainstorming and role play. In order to identify the effect of treatment on children's height and development, the data obtained was analyzed using paired t-test, while the analysis of differences between treatment groups was carried out using analysis of variance (ANOVA). The results showed that giving psychosocial parenting education significantly increased height, children's nutritional status based on height by age index, and improved cognitive development among toddlers. Giving multiple-nutrient biscuits and psychosocial parenting education significantly increased height and cognitive development among toddlers. In order to overcome children's growth and development problem, nutrition interventions need to be carried out along with the provision of education about maternal parenting to children.Despite the present of national policy support, the prevalence of early breastfeeding initiation in Indonesia are still low. Research has shown that health care workers are the most reliable source for breastfeeding advice, but sadly they were often lacking in capacity. The aim of the study to assess the involvement of civil society organization (CSO) and its associated factors in facilitating the implementation of Ten Steps for Successful Breastfeeding (TSSB) based on health care workers' perspectives in Malang and Sidoarjo districts, East Java Province, Indonesia. We used qualitative approach to in-depth interview 117 participants and conducted 14 FGDs in Sidoarjo and Malang East Java. the PARiHS framework was used to identify the role of CSO in facilitating the BFHI implementation from the health workers perspective to offer insight on the facilitation process and development of future recommendations. The study found that the health care workers' have good knowledge on the benefits of breastfeeding with significant portion of the knowledge that they hold are coming from trainings provided by the CSO. There was cultural context barriers within the community, where grandmothers are considered as an important influence factor esspecially for working mothers. The implementation of training by the CSO was considered appropriate due to its ability to address some pressing structural obstacles and provide not only training to improve evidence but also help in addressing other contextual barriers. The CSO has offered opportunities not only for dissemination of evidence-based intervention but also to close gaps on resources provision to attend courses.
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