Notes

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The study aimed to highlight the relationship between forensic science and endodontics by illustrating CBCT records can be used as legal evidence for forensic analysis and evaluate the effect of elevated temperature on the endodontically treated teeth.

The present study was conducted on 40 extracted permanent mandibular premolars, which were divided into two groups based on predetermined incineration temperature Group I - 400°C & Group II - 800°C subjected for 15 minutes holding time in a digital burnout furnace. The root canal treatment was performed for both the groups and a Pre-incineration CBCT scan was taken for both the groups as an ante-mortem data. Following heating analysis, root canal treated teeth were examined using a stereomicroscope at 20x resolution to evaluate the morphological changes. The post-incineration CBCT scan was taken as the post-mortem record for each group. Both ante-mortem records and post-mortem records were compared for the forensic analysis.

The endodontically treated teeth display a series of macroscopic and stereo-microscopic changes for each temperature scale. The CBCT records identify the thermal stress-induced 3D alterations in the gutta-percha filled teeth.

Knowledge of changes in human dentition and traces of the endodontically treated teeth can help forensic experts for the identification of the fire victims.
Knowledge of changes in human dentition and traces of the endodontically treated teeth can help forensic experts for the identification of the fire victims.
The aim of this study was to compare the accuracy of three electronic apex locators (EALs) (Propex Pixi, Mini Root ZX, Raypex 5) in determining working length (WL) under different environments (existence of blood-pulp/sodium hypochlorite in root canal space) using micro-computed tomography (micro-CT) measurements.

Twenty-five single-rooted human teeth that were scheduled for extraction were selected for the study. Measurements were performed with the Propex Pixi, Mini Root ZX, Raypex 5 in vivo conditions in the presence of NaOCl irrigant solution or blood-pulp tissue. After that the teeth were extracted and scanned using micro-CT. The measurements of WL obtained with the different EALs in different environments were statistically compared. Significance was set at P<0.05.

There were no significant differences among the WL measurements performed with EALs or micro CT groups under different clinical enviroments. All EALs tested gave reliable results in respect to apical constriction.

The accuracy of the tested EALs is not affected by pulp tissues and blood or NaOCl.
The accuracy of the tested EALs is not affected by pulp tissues and blood or NaOCl.
Despite the controversial results regarding the amount of arsenic (As) in mineral trioxide aggregate (MTA) and MTA-like cements, it is prudent to assess the effect of this heavy metal on pulpal cells and search for methods to attenuate its toxicity. This study investigated the toxic effect of As on pulpal-like cells and evaluated the influence of reduced glutathione (GSH) on As-induced toxicity.

The cytotoxicity of 50 µm As, 50 µm As+50 µM GSH, 50µm As+500 µM GSH or 50 µm As+5000 µM GSH on rat pulpal cells (RPC-C2A) was evaluated at 24 hours and 72 hours. Cell culture in fresh medium without experimental solution served as the control. Cell viability was measured by means of 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide (MTT) assay and the optical density was measured with microplate reader. The morphology of the cultured cells was observed under phase contrast microscope. Cytotoxicity data were analyzed by two-way ANOVA and Tukey post hoc tests (P<0.05).

There were statistically signi effect against As-induced toxicity. Future research is warranted on the clinical use of GSH with MTA and MTA-like cements to minimize initial inflammation resulting from As release during the setting of the aforementioned cements thus enhancing the success of procedures where these cements are placed in direct contact with vital pulp tissues.
The present study aimed to assess preoperative levels of patient anxiety and pain before root canal treatment, and to explore variables that may affect these levels.

Ninety-five patients presenting for an endodontic visit were recruited for the study. A questionnaire was administered. Visual analog scales were used to record levels of pain and anxiety. Data was tabulated, and analysis was performed using the Pearson Chi-Squire test with continuity correction, and the level of significance was set at 0.05 (P=0.05).

Anxiety was detected more frequently in females (60%) than in males (33%) (P=0.016). Sixty-two percent of patients who were waiting for a new treatment were anxious, compared to 39% of those who were returning to continue treatment (P=0.049). Sixty-nine percent of patients in pain reported being anxious (P=0.015). Patients aged 18-30 years reported more pain than those older than 30 years (P=0.023). Semagacestat solubility dmso Forty-three percent of new patients reported being in pain, whereas only 20% of patients returning for a treatment reported pain (P=0.027).

Anxiety associated with root canal treatment is prevalent, and it was reported primarily by young females who were presenting for a new treatment. Pain and anxiety are highly inter-related, and they are usually reduced after the first endodontic session.
Anxiety associated with root canal treatment is prevalent, and it was reported primarily by young females who were presenting for a new treatment. Pain and anxiety are highly inter-related, and they are usually reduced after the first endodontic session.
To evaluate cyclic fatigue and torsional resistance of Reciproc Blue R25 (VDW, Munich, Germany), WaveOne Gold Primary (Dentsply Maillefer, Ballaigues, Switzerland), ProDesign R (Easy Equipamentos Odontológicos, Belo Horizonte, Brazil), and X1 Blue File (MK Life, Porto Alegre, Brazil) nickel titanium (NiTi) martensite reciprocating instruments.

In each group, ten instruments were tested for cyclic fatigue resistance using a stainless-steel artificial canal (curvature angle of 80° and radius of 3 mm) and ten instruments for torsional failure according to ISO 3630-1 standard. The surface of the fractured instruments was examined under scanning electron microscopy (SEM) at ×250 magnification. The results were compared statistically with one-way ANOVA and post hoc Tukey tests and the alpha-type error was set at 5%.

X1 blue file and ProDesign Rinstruments showed highest time to fracture than Reciproc Blue and Wave One Gold (P<0.05). However, no differences were found between X1 Blue File and ProDesign R (Ps to fracture. SEM analysis of all instruments demonstrated typical failures features in both cyclic fatigue and torsional failure tests.Intrusion is the most severe luxation injury type, which results in both soft and hard tissue damage. In severe intrusions, the crown must be re-positioned in the arch to avoid periapical pathology and marginal bone loss. There is minimal information about the effect of treatment delay on pulpal and periodontal healing in intrusion trauma. The present paper reports on two cases of severe intrusive luxation applied late at different times treated with surgical extrusion. The first patient, an 11-year-old female, referred to Tokat GOP pediatric dentistry clinic three days after the intrusion tooth 21. The second patient, a 13-year-old male, referred to our clinic fifteen days after a traffic accident. The intruded teeth were positioned surgically and splinted. Surgical extrusion should be preferred as soon as possible to initiate root canal treatment in teeth, the crown of which is fully embedded in the alveolar bone.Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been associated with multiple entities and several types of cancers. They can be assumed as markers of inflammatory imbalance. The objective of this study is to evaluate the NLR and PLR in Peyronie's disease (PD) and to establish a comparison of its values in the acute and chronic stages. We recruited patients with PD from March 2018 to March 2019. The patients enrolled underwent medical and sexual history as well as a physical examination. The values of blood count of each patient were collected both in the acute and chronic stages. Wilcoxon test was used to compare the acute and chronic stage ratios. Kruskal-Wallis test was carried out to evaluate the impact of treatments on the ratios. To identify cutoff values, we used sensibility and specificity tables and receiver operating characteristic (ROC) curves. A total of 120 patients were enrolled. Their mean age was 55.85 (range 18-77) years and the mean penile curvature was 48.43° (range 10°-100°). In the acute stage, the mean NLR was 2.35 and the mean PLR was 111.22. These ratios, in the chronic stage, were 1.57 and 100.00, respectively. Statistically significant differences between acute and stable stages for both indices were found (NLR P less then 0.0001; PLR P= 0.0202). The optimal cutoff for classification in acute or stable stage was 2 for NLR and 102 for PLR. According to our results, with an ordinary blood count, we could have important indications regarding the disease stage of the patient, and consequently on the most appropriate type of therapy to choose.ERCP and EUS are complementary techniques in the management of biliary and pancreatic diseases. Combination of these two techniques can reach different levels of complexity with increasing rates of adverse events. In this article we propose a categorization of the relationship between EUS and ERCP based on whether EUS indicates, complements, facilitates or replaces ERCP. It has implications for the complexity of the technique, the training of the endoscopist and the necessary hospital resources. This classification can also be useful in planning endoscopist training and patient management.COVID-19 pandemic had a global impact on residency training and surgical training had seen the worst hit. In the current era, the minimal invasive surgery has become inherent component of any surgical speciality training and the COVID-19 crisis has affected the various components of this training including acquisition of knowledge, clinical judgement and technical competency. This impact, coupled with uncertainty in future training and job opportunities have jeopardized the current surgical trainees.Laparoscopic deroofing of liver cysts is widely accepted as the treatment of symptomatic huge liver cysts. As bile leakage is a common complication of this procedure, indocyanine green (ICG) imaging has played an active role in detecting intrahepatic biliary tract. However, infusion ICG imaging needs time rag after injection due to moving from bloodstream to bile, and also, additional injection is needed when the fluorescent imaging is not clear. To cover this weakness of ICG imaging, we first applied ICG imaging via 5-Fr endoscopic nasal biliary drainage (ENBD) during laparoscopic deroofing of liver cysts. This technique promptly gives us ICG imaging after ICG injection from ENBD; in addition, direct ICG imaging sometimes reveals minor leakage from sealing line and staple lines; therefore, we believe that direct ICG imaging via ENBD helps us to prevent post-operative bile leakage.
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