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Social factors involving pertussis along with flu vaccine uptake in pregnancy: a nationwide cohort study inside Britain utilizing electronic digital wellness information.
The aim of this study was to solve one of the current limitations for the characterization of the brain network in the Alzheimer's disease (AD) continuum. Nowadays, frequency-dependent approaches have reached contradictory results depending on the frequency band under study, tangling the possible clinical interpretations.

To overcome this issue, we proposed a new method to build multiplex networks based on canonical correlation analysis (CCA). Our method determines two basis vectors using the source and electrodelevel frequency-specific network parameters for a reference group, and then project the results for the rest of the groups into these hyperplanes to make them comparable. It was applied to (i) synthetic signals generated with a Kuramoto-based model; and (ii) a resting-state EEG database formed by recordings from 51 cognitively healthy controls, 51 mild cognitive impairment subjects, 51 mild AD patients, 50 moderate AD patients, and 50 severe AD patients.

Our results using synthetic signals showeng the limitations of possible frequency-specific conflicts. Additionally, our method supposes a novel approach for the construction and analysis of multiplex networks during AD continuum.The article summarizes the data on the number of conversion therapy legal bans aimed at changing sexual orientation and gender identity in countries around the globe; the content and the form of such prohibitions, the scope of their action by territorial criterion and the nature of the prohibition itself are analyzed; the draft laws, which are intended to legalize such bans in the national and territorial regime are studied; the thematic case law of individual countries is partly examined; countries where conversion therapy is promoted and explicitly authorized by public authorities are considered. According to the results of the study of more than half a hundred legal documents, the information obtained is distributed and organized into the following categories national and regional prohibition of conversion therapy, direct and non-direct prohibition of conversion therapy; ban in different parts of the world. The content highlights the characteristics of the existing prohibitions, such as the name of the delict; year of entry into force of the relevant legal act; prohibition of sexual orientation and/or gender identity activities; the circle of persons subjected to the prohibition; the circle of persons protected by the prohibition; peculiarities. The results of the study showed that there are currently 15 countries in the world (14 United Nations and 1 outside the United Nations) where conversion therapy is prohibited. Among them 5 countries have direct nationwide bans; 6 countries have non-direct nationwide bans; 3 countries have direct regional bans; 1 country has an non-direct regional ban. Conversion therapy is prohibited in 6 countries in the Americas; 1 Asian country; 4 European countries; 4 Oceania countries.The aim of the article is a comparative and legal study of corruption and measures to combat corruption in health care in Ukraine, using the experience of Georgia and the European Union. The materials of the research are the legislation of the European Union, Georgia, Ukraine, statistical information. The authors of the research have used the systematization method, comparative and legal method, analysis and generalization of statistical data. Corruption and corruption offences in the health system may lead to unpredictable consequences impacting accessibility, equity and health outcomes. Fighting against corruption in the health sector consists of the identification of specific forms of corruption and the implementation of effective anti-corruption measures, which must be designed to fit the context of a country's health system. A study of the experience of Georgia and the EU countries shows that, changes in the organization and management of the health system, financing of health care, provision of health services, increase access to medical services, reducing inequalities, financial risks reduction regarding expenditures on medical services, changing public opinion of the perception of corruption, transparency and accountability in the funding of medicine, the anti-corruption examination of legislative acts regulating the activity of healthcare in Ukraine, the formation of anti-corruption behaviour in society, active cooperation with civil society institutions are therefore of primary importance for Ukraine during the period of medical reform. Elimination of the reasons and conditions promoting the commission of corruption offences in the health system and the introduction of an effective anti-corruption strategy based on good governance, transparency and zero tolerance are among the priority areas for improving the current legislation of Ukraine in fighting against corruption in the field of healthcare.Organ donation is one of the topical issues in the field of medicine around the world. Although the practice of transplantation exists in most countries of the world, there are still many unresolved issues. One of them is the issues related to postmortem organ transplantation in Ukraine. Despite the significant increase in the scale of transplantation of human organs, tissues and cells, today there is a need to improve the mechanism of organ transplantation from deceased persons, both at the legal level and in the provision of medical services. Eprosartan price The purpose of the study is to consider problematic issues related to posthumous transplantation, in particular its legal support, ethical aspects, medical opportunities for improving the procedure for providing organs to the recipient, as well as looking for prospects for their resolution. To achieve this goal, an analysis of the existing regulatory framework in the field of transplantation was carried out, the experience of Ukraine and foreign countries on the issue under study was analyzed, the following methods were used comparative legal, statistical, induction, analysis, synthesis. Based on the study, the authors conclude that the regulation of transplantation in Ukraine should be not only at a high legal level, but also implemented in practice into the Unified State Information System for Organ and Tissue Transplantation, which will allow timely and efficient provision of organs to the recipient.The fundamental and fundamental human right that is central to the system of non-proprietary rights aimed at ensuring the natural existence of an individual is the human right to life. The development of a civilized world leads to a new subjective perception of people about the origin of man, his place in the ecosystem and outer space in general and the scope of human rights and their transformation in particular. Complications of social life in the modern world leads not only to the transformation of social relations and the rapid renewal of the entire legal framework, but also to a significant acceleration and deepening of the formation of new branches of national law. In the current legal reality, it is separately necessary to separate medical law. The creation of medical law as a new branch of law is a necessity of our time, which will allow us to more effectively regulate legal relations in the medical field. The Institute of Euthanasia, in turn, should take its place precisely in the framework of medical law, and should be considered as a system of legal norms aimed at regulating social relations arising from the deliberate deprivation of life of a patient in order to alleviate his suffering, establishing the subjective composition and special methods of legal regulation. A look at the institution of euthanasia as an integral element of medical law will provide an effective and differentiated legal regulation of the procedure for its implementation.Chronic obstructive pulmonary disease (COPD) is the major cause of chronic morbidity and mortality throughout the world. USAID Health Care Improvement Project (HCI) had collaborated with the Ministry of Labor, Healthcare and Social Affairs of Georgia in 2012-2014 to improve quality of care for high-burden and under-diagnosed diseases, including asthma and COPD. The Aim of the study was to evaluate the effectiveness (quality, consistency and continuity) of medical care in COPD patients in one of the regions of Georgia after 5 years from the ending of the project. The received results of our research were compared to the data from USAID HCI Project. In order to evaluate the effectiveness of medical care, 7 rural primary care units and 1 hospital have been selected. Information was gathered with standardized questionnaires from providers, patients and medical records 42 physicians and 83 patients were interviewed, 152 medical records were reviewed. Research period was defined from March 2017 till March 2019. Research protocol is approved by an Ethical Committee Review Board at ATSU. All indicators showing the quality and effectiveness of COPD management (prescription of COPD controller medications, bronchodilators, documented procedures, etc) are improved. Improvement tendency is obvious in all aspects of treatment/management, except spirometry results recorded, which is 4% less compared to the project results. Documentation from the primary care units showed decreased indicator of counseling provided for smoking cessation by 9%. Based on our data the sustainability in the treatment and management of COPD is still in progress. Two main areas need to be paid special attention to patient consultation/education and timely diagnosis of the disease.Protection of maternity and child health is of great medical and social importance. Provision of medical care to women and children in Kazakhstan is the major task for state policy. Still, the data on epidemiological indicators of perinatal care in Kazakhstan are rather limited. This study was aimed at assessment of perinatal care indicators in Almaty, Kazakhstan Republic, over the period from 2013 to 2017. The data on demographic characteristics of study population were obtained from online platform of the Republican Center for Health Development. The analysis of perinatal indicators was carried-out on the basis of statistical reporting form No. 32. We relied on the standard statistical formulas to calculate epidemiological indicators. All statistical tests were performed in SPSS software, Version 17.0 for Windows. The crude birth rate over five years remained stable and was within the range of 25,975-26,289 per 1,000 population. The abortion rate constituted 2.018-2.272 per 1,000 population. The abortion raaimed at ensuring proper monitoring over maternity health indicators.The aim of the paper is to analyze the mechanism of compulsory licensing of medicines in the context of the COVID-19 pandemic. The methodological basis of the study encompasses the general and special methods of scientific inquiry (formal logical method, comparative law, structural-logical method, analysis and synthesis methods). The ways and possibilities of balancing the interests of rights-holders and society's interests (in particular patients' interests) have been studied. It is highlighted that compulsory licensing must be employed exclusively in view of the principle of proportionality, since any restrictions on human rights, including patent rights, must comply with the legislation in force and be proportionate to the potential threat. Comprehensive attention is paid to the interests of right holders (in our case, medicines manufacturers), their protection as well as the ways they abuse their patent rights. It is underlined that access to medicines and treatment is a prerequisite for the realization of the right to health and, consequently, is of social interest.
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