Notes

Growing Solvatochromic Push-Pull Chemical dyes for Keeping track of the particular Lipid Get involving Biomembranes in Live Cells.
Intelligent packaging with a pH indicator has been a hot research topic due to its extra active role compared with traditional ones. Considering the possible toxicity of synthetic pH sensitive pigments, natural pigments are promising alternative indicators. This work aimed to develop and characterize active and pH sensitive films based on psyllium seed gum (PSG) incorporated with free and microencapsulated mulberry pomace extracts (MPE). Compared with PSG control film, PSG-MPE films showed an increase in total phenolic content and DPPH scavenging activity, and decrease in surface hydrophobicity, lightness, and tensile strength. The molecular interactions between PSG and MPE were confirmed by thermal and microstructure analysis. Moreover, PSG-MPE films displayed wide color differences from red to blue at pH 2.0 - 12.0. PSG-based films containing 10% free and microencapsulated MPE demonstrated better overall performance and economy in packaging applications, which could be used as promising active and pH-sensitive food packaging materials.The research aimed to study the effect of stevia, xylitol, and corn syrup on the physical, physicochemical, and sensory properties of velvet tamarind chewy candy (VTCC). The content of sweeteners was optimized using stevia (5.5-6%), xylitol (5.5-6%), and corn syrup (7.5-8.5%) by mixture design (d-optimal) with 3 centerpoints and response surface methodology (RSM). The sweeteners in optimized VTCC consisted of velvet tamarind powder (40.5%), water (40%), stevia (6%), xylitol (6%), and corn syrup (7.5%) which provided the approximation error between prediction and observation values of color (a* and b*), hardness, adhesiveness, gumminess, bioactive activities, and sensory properties within the range of 0.07-9.69%. The optimized VTCC using stevia and xylitol can reduce the sugar content by up to 60%. The sensory preference scores of VTCC from consumer acceptance were slightly like (6.1-6.9) which indicated that the VTCC with stevia and xylitol can provide satisfaction in all evaluated attributes and can be applied to this concept to create fruit chewy candy using stevia and xylitol.
Benign emptying of the post-pneumonectomy space (BEPS) is characterized by a decreased air-fluid level after pneumonectomy, albeit without the presence of bronchopleural fistula (BPF).

A 66-year-old man with lung cancer diagnosed clinical stage IIIA received right pneumonectomy. The air-fluid level of the right pleural cavity suddenly dropped on the 19th postoperative day. Although we were unable to detect the fistula of the bronchial stump using bronchoscopy, we performed re-operationt. Although a pressure of 30 cmH
O was applied into the airway and air leakage from the bronchial stump was not detected, we covered the bronchial stump with the omentum. read more Because the air-fluid level of the right pleural cavity decreased 9 days after the 2nd operation without any symptom, we diagnosed the condition as BEPS.

If a fistula of the bronchial stump cannot be identified using bronchoscopy or thoracoscopy, then determining whether it is BEPS or microscopic BPF can be difficult.

It is currently unclear what the optimal strategy is in this case.
It is currently unclear what the optimal strategy is in this case.
Mediastinal hemangiomas are a rare entity frequently developing in the anterior mediastinum. They may exhibit an infiltrating appearance into the surrounding tissue, and extensive surgery is often required despite its benign nature. We report a case of a mediastinal hemangioma mimicking an invasive tumor growth requiring a combined resection of the lung and diaphragm.

An asymptomatic 73 year-old-man presented with a 50 mm-sized mass on his chest radiography. A combined resection of the mediastinal mass with the part of the lower lobe of left lung and diaphragm not necessitating a patch repair was performed. The pathological findings were compatible with a diagnosis of a mediastinal hemangioma. Only fibrous adhesions were observed between the tumor and resected lung and diaphragm without any histological invasion.

While imaging examinations play a key role in determining a preoperative diagnosis, mediastinal hemangiomas may pose a diagnostic challenge mainly due to its rarity. With a clinical suspicion of a hemangioma during the diagnostic work up, a dynamic CT might be helpful.

In mediastinal hemangiomas, a preoperative diagnosis is essential in order to avoid extensive surgery. A hemangioma should be raised as a differential diagnosis for anterior mediastinal tumors, especially in cases with an infiltrative appearance that suggests the necessity for a combined resection of the surrounding organs.
In mediastinal hemangiomas, a preoperative diagnosis is essential in order to avoid extensive surgery. A hemangioma should be raised as a differential diagnosis for anterior mediastinal tumors, especially in cases with an infiltrative appearance that suggests the necessity for a combined resection of the surrounding organs.
The hepatic arteries may be subject to anatomical variations that can cause operating difficulties with a risk of iatrogenic vascular injuries. A perfect knowledge of anatomy is an essential prerequisite for both surgeons and interventional radiologists.

During a duodenopancreatectomy for a pancreatic head tumor in a 46-year-old man, we observed an anatomical variation regarding the course of the right hepatic artery (RHA). Indeed, RHA arose from the proper hepatic artery (PHA) at the left edge of the hepatoduodenal ligament and instead of crossing the common hepatic duct (CHD) posteriorly which is the usual course, it passed overhead before ascending and finishing its course in the liver hilum.

Anatomical variations of the hepatic arteries can be explained by the partial or complete persistence of the fetal model. Variations in the RHA may concern its number, origin or route. A prebiliary course of the RHA has been described with a prevalence ranging from 15 to 25% depending on series. The high sensitivity of Multidetector Computed Tomographic Angiography (MCTA) allows performing a complete vascular mapping, which remains essential before any Hepato-Pancreato-Biliary (HPB) surgery.

This case confirms once again the frequency of anatomical variations of the hepatic arteries, and underlines the value of CT Angiography to detect them in order to best plan any HPB surgery, where RHA remains an essential anatomical landmark that all surgeons must keep in mind in order to avoid any unfortunate incidents.
This case confirms once again the frequency of anatomical variations of the hepatic arteries, and underlines the value of CT Angiography to detect them in order to best plan any HPB surgery, where RHA remains an essential anatomical landmark that all surgeons must keep in mind in order to avoid any unfortunate incidents.
Dislocation is a severe complication after total hip arthroplasty (THA). It is one of the most common reasons for failure and revision surgery. This is the first case of a documented simultaneous bilateral dual mobility (DM) THA dislocation.

A forty-nine-year-old man presented with bilateral hip pain, immobility and deformity. X-ray images demonstrated simultaneous bilateral posterior THA dislocation. Previously, the patient had presented atraumatic dislocations recurrently. When he was thoroughly re-interrogated, he complained of uncontrolled and generalized muscle contractions, which were compatible with myoclonus due to hepatic encephalopathy (HE). Multidisciplinary treatment was performed satisfactorily to control myoclonus symptomatology and to prevent dislocation.

Patient's most important risk factor was a neuromuscular disorder, which we initially gave little notice and undervalued. HE is a serious but reversible syndrome, observed in patients with liver dysfunction. It leads to a wide spectrum oed, and appropriate surgical approach, technique and implants have to be collectively used to reach a strategy that mitigates and ideally prevents dislocation.The effect of hydrolysis degree of gallotannins (GT, 1 mg/g) on cross-linking of nano-size collagen catalyzed by laccase (12 U/g) was studied, and the antibacterial properties of GT hydrolysates (HGT)-laccase (Lac) collagen films on minced cod were also investigated. The results showed that the tensile strength of HGT-Lac films (87.23-100.77 MPa) was higher than those added HGT alone (85.59-95.58 MPa) under the same hydrolysis degree of GT. Compared to the denaturation temperature (78.05 °C) of pure nano-size collagen film without addition of HGT and laccase, the denaturation temperature of HGT (80.75-86.30 °C) and HGT-Lac (91.97-101.64 °C) films increased greatly, especially for HGT-Lac films. Moreover, both HGT and HGT-Lac films showed some mild antibacterial properties for minced cod during storage at 4 °C for 8 days. Therefore, the combination of HGT and laccase could improve the performance of nano-size collagen film and extend the application of collagen in biodegradable/edible packaging.To investigate the effect of relative humidity (RH) on chilling injury (CI), zucchini fruit were stored in cold rooms (4 ± 0.4 ℃) with different RHs (near-saturated RH [NSH] with 96-100% and normal RH with 72-76% served as control). Storage in NSH delayed weight loss and CI, maintained firmness and skin color. Higher antioxidant enzyme activities and greater scavenging capacities of free radicals were found in NSH-fruit than in the control fruit. The decrease of the unsaturated fatty acids was delayed in NSH-fruit due to lower activities of related membrane lipid degrading enzymes as compared to the control fruit. NSH-fruit also maintained higher activities of energy metabolism-associated enzymes than control fruit, leading to high levels of adenosine triphosphate (ATP). Taken together, we attributed the alleviation of CI by NSH storage to its enhancement of antioxidant capacities and its effect on maintaining higher energy status in zucchini fruit.The valorization of the brewer's spent grain (BSG) generated in a craft beer industry was studied by subcritical water hydrolysis in a semi-continuous fixed-bed reactor. Temperature was varied from 125 to 185 °C at a constant flow rate of 4 mL/min. Biomass hydrolysis yielded a maximum of 78% of solubilized protein at 185 °C. Free amino acids presented a maximum level at 160 °C with a value of 55 mg free amino acids/gprotein-BSG. Polar amino acid presented a maximum at lower temperatures than non-polar amino acids. The maximum in total phenolic compounds was reached at 185 °C. This maximum is the same for aldehyde phenolic compounds such as vanillin, syringic and protocatechuic aldehyde; however, for hydroxycinnamic acids, such as ferulic acid and p-coumaric, the maximum was obtained at 160 °C. This allows a fractionation of the bioactive compounds. Subcritical water addresses opportunities for small breweries to be incorporated within the biorefinery concept.Heat processing of ready-to-drink beverages is required to ensure a microbiologically safe product, however, this can result in the loss of bioactive compounds responsible for functionality. The objective of this study was to establish the thermal stability of a novel dihydrochalcone, 3',5'-di-β-d-glucopyranosyl-3-hydroxyphloretin (2), 3',5'-di-β-d-glucopyranosylphloretin (3) and other Cyclopia subternata phenolic compounds, in model solutions with or without citric acid and ascorbic acid. The solutions were heated at 93, 121 and 135 °C, relevant to pasteurisation, commercial sterilisation and ultra-high temperature (UHT) pasteurisation, respectively. For most compounds, the acids decreased the second order reaction rate constants, up to 27 times. Compound 2 (46.29 ± 0.53 (g/100 g)-1 h-1), and to a lesser extent compound 3 (5.94 ± 0.01 (g/100 g)-1 h-1) were the most thermo-unstable compounds when treated at 135 °C without added acids. Even though differential effects were observed for compounds at different temperatures and formulations, overall, the phenolic compounds were most stable under UHT pasteurisation conditions.
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