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CONCLUSION Make a habit of a healthy lifestyle in their daily life by doing physical activity regularly and good eating pattern to forestall hypertension. Copyright © 2019 Elida Normiaty Purba, Heru Santosa, Fazidah Aguslina Siregar.BACKGROUND The lives of individuals diagnosed with HIV and the subsequent illness, AIDS, were often chaotic because these individuals deal with the physical, emotional, and interpersonal sequelae of this illness. Depressive symptoms and stress were common and impact on functioning, quality of life, and health status, highlighting the importance of diagnosis and treatment of patients with HIV infection. Psychiatric clinical practice and rating scales have come to play an ever-increasing role both in determining specific symptoms and diagnosing an individual condition. Descriptive reports of psychiatric morbidity among those with HIV infection, that relied primarily on self-report rating scales, described high rates of symptomatic depression and stress. AIM This study aimed to determine the proportion of depression among people living with HIV/AIDS using the BDI-II and PSS to determine a relationship between symptoms of depression and stress with CD4 counts. METHODS This study was a numerical correlative analytic study with a cross-sectional study approach that assessed the correlation between stress, depression and CD4 level in people with HIV/AIDS that were receiving ARV therapy in the Voluntary Counselling Test (VCT) Polyclinic of General Hospital Haji Medan by recruiting 46 subjects. CD4 level was examined in the Pramita Medan laboratory. RESULTS When analysis of BDI-II level and CD4 scores were done, a significant correlation was found (P less then 0.05). The strength of the relationship between the BDI score and the CD4 score was 0.548 revealing a positive correlation with moderate correlation strength. CONCLUSION We have shown a significant relationship between depression, stress and CD4 level among people with HIV/AIDS in Medan, Indonesia. Psychological distress may affect the immunity in infected people, leading to the disease progressivity. Copyright © 2019 Elmeida Effendy, Mustafa M. Amin, Lidya de Vega, Nurul Utami.BACKGROUND The use of albumin in the critical care setting is a very controversial issue. Low serum albumin concentration in critical illness is associated with a poor outcome. AIM We aimed to evaluate the influence of albumin level in critically ill children to the length of stay and mortality in the Pediatric Intensive Care Unit (PICU) Haji Adam Malik General Hospital, Medan, Indonesia. METHODS The study used an observational method with a cross-sectional design. The population of the study was all patients with major postoperative surgery and critically ill that admitted to the PICU at Haji Adam Malik Hospital from the period of June 2008 to September 2008. The albumin level of the subjects was determined on the first day admitted. RESULTS The group with hypoalbuminemia ( less then 3 g/dL) was given albumin supplementation according to a protocol in the PICU. The group with hypoalbuminemia have an average length of stay 7.6 days (9.7%) and mortality of 12 subjects (36.4%). The group with normal albumin level have 4.7 days (5.0%) and mortality 13 subjects (37.1%). There was no significant effect of albumin level to mortality. CONCLUSION Albumin level did not affect the length of stay and mortality in PICU. Copyright © 2019 Gema Nazri Yanni, Munar Lubis, Muhammad Ali.BACKGROUND Hepatocellular carcinoma (HCC) is the fifth most common malignancy. The Barcelona Clinical Liver Cancer System (BCLC), guides the treatment of patients with HCC. Platelet to lymphocyte ratio (PLR) is an inflammatory marker used as a prognostic factor disease of HCC. An increase in PLR indicates higher host's inflammatory response and is associated with aggressive HCC behaviour, according to BCLC. AIM This study aims to determine the PLRs between among the degrees of BCLC (The Barcelona Clinic Liver Cancer) in HCC patients at Haji Adam Malik General Hospital in Medan during 2015-2016. METHODS This retrospective study involved 166 patients with HCC who were then classified by the BCLC guidelines. PLRs among the patient's degrees of BCLC were compared using Kruskal Wallis test. RESULTS A total of 166 HCC patients, 129 (77.7%) were men and 37 (22.3%) were women. The PLR value has a median value of 17841with the lowest value of 1776 and the highest value of 223684. There were differences in PLR levels with various BCLC stages in patients with HCC at Haji Adam Malik Hospital during 2015-2016 (p = 0.026). CONCLUSION There were differences in PLR levels with various BCLC stages in patients with HCC at Haji Adam Malik Hospital during 2015-2016. Copyright © 2019 Gontar Alamsyah Siregar, Dedi Irwansyah.BACKGROUND The most widely used tumour markers, especially in colorectal malignancy, is Carcinoembryonic antigen (CEA). AIM This study was aimed to investigate CEA value among the degree of differentiation and tumour location. METHODS A cross-sectional analytical study was used in this study on eighty consecutive patients with colorectal carcinoma (CRC) at Adam Malik General Hospital and Permata Bunda Hospital, Medan, Indonesia. All data were analysed using SPSS for Windows version 21. RESULTS They were rectal cancer 49.4%, left-sided colon cancer 43.2% and right-sided colon cancer 6.2%. Histopathology findings were well-differentiated 40.7%, moderate differentiated 32.1% and poorly differentiated 25.9%. Sunitinib There were no correlations between CEA level and haemoglobin level, white blood cells count, and platelet count. There was no significant difference between CEA and location of the tumour (p = 0.70), although CEA level was significantly differenced among histopathology findings (p = 0.03). CEA levels were and associated with the degree of differentiation. CONCLUSION CEA levels increased in well-differentiated colorectal carcinoma especially in rectal cancer. Copyright © 2019 Gontar Alamsyah Siregar, Henry Sibarani.BACKGROUND Soil-transmitted helminth (STH) infection remains of public health importance, particularly in developing countries. North Sumatra province of Indonesia has reported high prevalences of STH in many of its districts. AIM In this study, we aimed to determine the prevalence of STH and evaluated STH knowledge and risk behaviours of school children in Mandailing Natal district. METHODS We conducted a cross-sectional study in two primary schools in Mandailing Natal district, North Sumatera province, Indonesia. Data were collected directly from the subjects using a questionnaire after receiving consent from their parents. A stool sample was also collected to determine the STH status of each subject. Samples were then transported to the parasitology laboratory at Universitas Sumatera Utara in Medan to be analysed by a trained analyst. Kato-Katz method was used to prepare the slides (World Health Organization, 2002). The intensity of infection is classified into light, moderate and heavy infection. RESULTS Prevalence of STH infections were 76.
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