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To synthesize original articles exploring the effects of sleep restriction on cognitive performance specifically for Elite Cognitive Performers, i.e. those who engage in cognitively demanding tasks with critical or safety-critical outcomes in their occupation or area of expertise.
Backward snowballing techniques, gray literature searches, and traditional database searches (Embase, MEDLINE, Web of Science, Google Scholar, PSYCinfo, and SportDiscus) were used to obtain relevant articles. A quality assessment was performed, and the risk of training effects was considered. Results were narratively synthesized. Fourteen articles fit the criteria. Cognitive outcomes were divided into three categories defined by whether cognitive demands were "low-salience," "high-salience stable," or "high-salience flexible."
Low-salience tests (i.e. psychomotor vigilance tasks & serial reaction tests), mainly requiring vigilance and rudimentary attentional capacities, were sensitive to sleep restriction, however, this did not necessarily translate to significant performance deficits on low-salience occupation-specific task performance. High-salience cognitive outcomes were typically unaffected unless when cognitive flexibility was required.
Sleep restriction is of particular concern to occupations whereby individuals perform (1) simple, low-salience tasks or (2) high-salience tasks with demands on the flexible allocation of attention and working memory, with critical or safety-critical outcomes.
Sleep restriction is of particular concern to occupations whereby individuals perform (1) simple, low-salience tasks or (2) high-salience tasks with demands on the flexible allocation of attention and working memory, with critical or safety-critical outcomes.Kinetic simulations of the thermoluminescence characteristics of LiFMg, Ti are reviewed in the framework of conduction band/valence band models. Delocalised recombination models have been mainly applied to the simulation of glow peak shapes, although comparison with experimental data has proven difficult if not impossible due to the scarcity of materials with demonstrably proven 'single-peak' glow curves. The delocalised models are incapable of the simulation of TL dose response linear/supralinear behaviour and the dependence of the supralinearity on particle energy. These characteristics require the incorporation of localised, nanodosimetric, recombination processes in the TL mechanisms. These investigations have simulated many of the TL characteristics of LiFMg, Ti in kinetic models based on a mixture of both delocalised and localised recombination.Maternal childhood maltreatment experiences (CMEs) may influence responses to infants and affect child outcomes. We examined associations between CME and mothers' neural responses and functional connectivity to infant distress. We hypothesized that mothers with greater CME would exhibit higher amygdala reactivity and amygdala-supplementary motor area (SMA) functional connectivity to own infant's cries. Postpartum mothers (N = 57) assessed for CME completed an functional magnetic resonance imaging task with cry and white-noise stimuli. Amygdala region-of-interest and psychophysiological interaction analyses were performed. Our models tested associations of CME with activation and connectivity during task conditions (own/other and cry/noise). Exploratory analyses with parenting behaviors were performed. Mothers with higher CME exhibited higher amygdala activation to own baby's cries vs other stimuli (F1,392 = 6.9, P less then 0.01, N = 57) and higher differential connectivity to cry vs noise between amygdala and SMA (F1,165 = 22.3, P less then 0.001). Exploratory analyses revealed positive associations between both amygdala activation and connectivity and maternal non-intrusiveness (Ps less then 0.05). Increased amygdala activation to own infant's cry and higher amygdala-SMA functional connectivity suggest motor responses to baby's distress. These findings were associated with less intrusive maternal behaviors. read more Follow-up studies might replicate these findings, add more granular parenting assessments and explore how cue processing leads to a motivated maternal approach in clinical populations.Pollinator declines have been documented globally, but little information is available about native bee ecology in Midwestern U.S. agriculture. This project seeks to optimize pollinator support and weed suppression in a 3-yr crop rotation with a fallow growing season. During fallow, one of five cover crop treatments (T1 crimson, red, and ladino clover and Bob oats [Fabales Fabaceae - Trifolium incarnatum L., Trifolium pratense L., Trifolium repens L., and Cyperales Poaceae - Avena sativa]; T2 crimson clover and oats; T3 red clover and oats; T4 ladino clover and oats; T5 no cover crop; T6/control winter wheat [Cyperales Poaceae - Triticum aestivum] L.) was seeded in one-half of 25 agricultural fields, whereas wheat was left unharvested in the other half as a comparison. Treatments that provide season-long floral resources support the greatest bee diversity and abundance (T1), and treatments with red clover support declining (Hymenoptera Apidae) Bombus species (T1 and T3). Late-season floral resources may be important, yet limited (T1 and T4), and some species of agricultural weeds provide floral resources. Floral diversity may be less important than flower abundance or timing for pollinator diversity (T1-T4). Weed diversity was greatest in the no cover crop treatment (T5), least in winter wheat (T6), and intermediate in cover crop treatments (T1-T4) with no differences in weeds of economic concern. Wheat suppresses weeds but does not provide floral resources for pollinators. These results may also be applicable to marginal lands taken out of cultivation or field margin pollinator plantings in a typical corn-soybean rotation. Floral resource availability across the landscape is critical to maintain pollinator diversity.Different types of DNA damage can initiate phosphorylation-mediated signalling cascades that result in stimulus specific pro- or anti-apoptotic cellular responses. Amongst its many roles, the NF-κB transcription factor RelA is central to these DNA damage response pathways. However, we still lack understanding of the co-ordinated signalling mechanisms that permit different DNA damaging agents to induce distinct cellular outcomes through RelA. Here, we use label-free quantitative phosphoproteomics to examine the temporal effects of exposure of U2OS cells to either etoposide (ETO) or hydroxyurea (HU) by monitoring the phosphorylation status of RelA and its protein binding partners. Although few stimulus-specific differences were identified in the constituents of phosphorylated RelA interactome after exposure to these DNA damaging agents, we observed subtle, but significant, changes in their phosphorylation states, as a function of both type and duration of treatment. The DNA double strand break (DSB)-inducing ETO invoked more rapid, sustained responses than HU, with regulated targets primarily involved in transcription, cell division and canonical DSB repair.
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