Notes

Mini-review: Synaptojanin 1 and its particular significance in membrane layer trafficking.
Mucosal diseases of the oral cavity arerelatively common, and patients oftenseek initial assessment from theirgeneralpractitioner.

The aim of this article is to provide anoverview of common oral mucosal diseases to help with formulating a differential diagnosis and stratifying theurgency of referral.

Pathological mucosal conditions of the oral cavity and jaws commonly present asa mucosal ulcer or a white, red or pigmented lesion. In this review, the authors outline the most common conditions organised according to their clinical presentation and describe their typical appearance and management.
Pathological mucosal conditions of the oral cavity and jaws commonly present as a mucosal ulcer or a white, red or pigmented lesion. In this review, the authors outline the most common conditions organised according to their clinical presentation and describe their typical appearance and management.
Orofacial problems present frequently toprimary care providers. Many of these problems have a surgical solution. Some may require minor procedures, while others require major maxillofacial surgery.

The purpose of this article is to illustratehow some common orofacial presentations can be investigated and solutions found in conjunction with oral and maxillofacial surgeons.

This article outlines a method of approach for some of the issues with which patients present to their primary healthcare provider that may be resolved using skills and techniques of maxillofacial surgery.
This article outlines a method of approach for some of the issues with which patients present to their primary healthcare provider that may be resolved using skills and techniques of maxillofacial surgery.
Oral health and general medical health are intimately linked. However, medical and dental practitioners often work in isolation from each other and have separate training, funding, regulatory andadministrative systems.

The aim of this article is to explore thehistory behind the divide between medicine and dentistry, and the challenges this raises.

The siloed nature of the two professional groups may be attributed to historical backgrounds, deficiencies in interdisciplinary education, government funding discrepancies and differing models of care. The two professions haveevolved with different social drivers and scientific underpinnings, with only arecent appreciation of the many connections between the health of themouth and the health of the body. #link# Solutions to overcome this divide should be considered in order to ensure better outcomes for patients, the community and perhaps the professions themselves.
Reparixin of the two professional groups may be attributed to historical backgrounds, deficiencies in interdisciplinary education, government funding discrepancies and differing models of care. The two professions have evolved with different social drivers and scientific underpinnings, with only a recent appreciation of the many connections between the health of the mouth and the health of the body. Solutions to overcome this divide should be considered in order to ensure better outcomes for patients, the community and perhaps the professions themselves.
Dental abscess as an end stage of dental disease is common in the community, and patients with dental abscesses are likely to seek care from their primary health provider. Once the infection has spread beyond the confines of the jaws, there is an increasing risk of airway obstruction and septicaemia. If treated with antibiotics alone, the infection will not resolve and will become progressively worse.

This article reviews the pathophysiology, demographics and management of severe odontogenic infections. It includes evidence-based studies of a large number of cases treated at a single tertiary hospital.

Prompt assessment and referral to a tertiary hospital is required for cases at risk of airway compromise. The morbidity and mortality of cases is presented in this article, with discussion of risk factors and the financial burden on the health system.
Prompt assessment and referral to a tertiary hospital is required for cases at risk of airway compromise. The morbidity and mortality of cases is presented in this article, with discussion of risk factors and the financial burden on the health system.
An orthopantomogram (OPG) is a common radiograph used to identify thehard tissues of the oral cavity and surrounding skeletal structures. It is an extra-oral radiograph that approximates the focal trough of the mandible. Although resolution is not as detailed as intra-oral radiographs for examination of the teeth, gross changes in calcification of the dental structures, and changes in ossification of the underlying mandible and maxilla can aid in identification of dental disease such as caries (decay), periodontal bone loss, and abscess and cyst formation.

This article outlines key anatomical features identifiable in an OPG and illustrates some common pathology thatmay be seen.

The large amount of data visible on an OPG may appear daunting to the viewer unless a systematic approach is used to examine structures present. Distortion due to flattening of the curve of the mandible and dentition will give an overall view of these structures and requires the viewer to reinterpret these intheir mind for a three-dimensional appreciation of the image.
The large amount of data visible on an OPG may appear daunting to the viewer unless a systematic approach is used to examine structures present. Distortion due to flattening of the curve of the mandible and dentition will give an overall view of these structures and requires the viewer to reinterpret these in their mind for a three-dimensional appreciation of the image.Classical Hodgkin lymphoma (HL) patients achieve excellent outcomes; therefore, treatment de-escalation strategies to spare toxicity have been prioritized. In a large randomized trial of early stage HL patients, omission of chemotherapeutic agents including bleomycin from the standard ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) regimen was not found to be non-inferior; however the effect of partial omission is unknown. We investigated the effect of bleomycin omission on outcome for 150 early stage HL patients. At eight years, freedom from relapse was 99% for both patients who received complete or incomplete bleomycin, which is reassuring for patients requiring bleomycin omission due to toxicity.
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