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Nodular eruption after botulinum neurotoxin type-A (BoNT-A) treatment is exceedingly rare, and the pathogenesis is poorly understood. This case series reports three patients that developed nodular eruptions following administration of Botox® (onabotulinum neurotoxin type A (ONA) injections). These patients had undergone multiple treatments before and after development of the eruptions which were uneventful. In addition to this, we have reviewed the published literature regarding this condition and have compared and contrasted the similarities and differences with regards to the clinical presentation and treatment with our patient cohort. This case series aims to raise awareness of this rare condition, its importance in relation to patient consent and provides a simplified management approach based on our experience. Further evaluation is needed to determine treatment consensus but conducting such research may prove to be challenging due to this condition being an infrequent encounter.
In recent times, the assessment of patient satisfaction has become an essential tool for measuring the effectiveness of healthcare delivery. However, not a lot of work has been done in Pakistan, even less so in comparing it across different hospital systems in the country. This research aims to fill that gap and be the first to compare satisfaction levels in a military and public hospital.
To assess patient satisfaction in different hospital systems of Pakistan and compare their outcomes.
A cross-sectional study was undertaken between October 2019 and April 2020 among376 patients; 193 from Combined Military Hospital, Lahore (CMH) and 183 from Jinnah Hospital, Lahore. The questionnaire used for the study was the Short-Form Patient Satisfaction Questionnaire - 18, and convenience sampling was used to select participants. selleck chemicals llc Data was entered and analysed on Statistical Product and Service Solutions (SPSS) version 21 (IBM Corp., Armonk, NY).
The majority of participants were male (71.2%), entitled to free he1.2%), entitled to free healthcare (58.4%), and employed (59.7%). It was found that CMH Lahore scored better in all seven domains of patient satisfaction (p less then 0.03 individually), with significant differences in six general satisfaction, interpersonal manner, communication, financial aspects, time spent with the doctors, and accessibility and convenience. Overall, waiting times and entitlement to free healthcare were established to be major determinants of satisfaction, with CMH having shorter waiting times and providing free treatment to a larger number of patients. The mode waiting time in CMH was 1 - 15 minutes (44.9%) as compared to 15 - 30 minutes (50.9%) in Jinnah Hospital. Additionally, 78.2% of patients were entitled to free healthcare in CMH, compared to 35.5% in Jinnah Hospital. Conclusion Patient satisfaction was found to be significantly better in CMH in six out of seven domains studied. Further work needs to be done in its assessment, as well as in its role in healthcare policies.Crohn's disease affects individuals across all age groups. However, given that it is more prevalent in younger adults, less attention is typically paid to elderly-onset Crohn's disease. The incidence of late-onset inflammatory bowel disease is around 8 per 100,00 patients per year in the United States. The hallmark symptoms of Crohn's, such as abdominal pain, diarrhea, and weight loss, may be absent in elderly patients, therefore making it more challenging to reach a diagnosis and initiate treatment in a timely manner. Crohn's disease can lead to multiple complications, including abdominal abscess, enteroenteric or perianal fistulas, and bowel obstruction. Nevertheless, it is highly uncommon to have bowel obstruction as the initial sign of the disease.Dengue infection can cause a wide spectrum of presentations extending from simple self-limiting febrile illness to severe dengue, including dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Dengue associated hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition characterized by the uncontrolled activation of macrophages and T cells, eliciting clusters of symptoms and signs and abnormal biochemical parameters. Herein we report a 28-year-old Sri Lankan female with no past medical history who presented with dengue hemorrhagic fever and diabetic ketoacidosis complicated with hemophagocytic lymphohistiocytosis. She was treated with a three-day course of intravenous methylprednisolone in addition to standard care for diabetic ketoacidosis and dengue hemorrhagic fever. She made an uneventful recovery.The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Wuhan, China, and subsequently spread worldwide affecting all ages including newborns. The cases of coronavirus disease 2019 (COVID-19) are very less in neonates and they recover well with supportive treatment. Though the vertical transmission of infection is scarcely found, to get rid of acquiring infection by horizontal transmission one should screen all pregnant women and ensure standard infection control measures and monitoring of newborns at risk of COVID-19. Neonates may present as a refusal to feed, feeding intolerance, fever, pneumonia, shortness of breath, and lethargic. Based on available evidence, antivirals like lopinavir, ritonavir, remdesivir specific medication like chloroquine/hydroxychloroquine, azithromycin, corticosteroids, and intravenous gamma globulin, are not recommended, so early detection and supportive treatment is needed for an optimal outcome.Myxofibrosarcoma is a soft tissue neoplasm that usually affects the extremities of the elderly. It usually presents as a slow-growing painless mass that can metastasize to the lung and bone. However, the reported incidence of primary osseous myxofibrosarcoma is very low. Moreover, the metastatic pattern of these bone tumors is largely unknown. We describe a unique case of a young Caucasian male with symptomatic low-grade myxofibrosarcoma arising in the left clavicle, who presented with multiple bone metastases.Inappropriate spacing is one of the major problems in tomato production at the study area. A field experiment was conducted to determine inter- and intrarow plant spacing for yield and yield components of tomato at Shewarobit, central rift valley of Ethiopia, under irrigation condition. The treatment comprises of three intrarow spacing (20, 30, and 40 cm) and four interrow spacing (60, 80, 100, and 120 cm) replicated three times and arranged in randomized complete block design using tomato variety Weyno. Data collected on fruit yield and yield components were analysed using SAS. The main effect of interrow spacing significantly affected marketable fruit, unmarketable fruit, marketable fruit number, unmarketable fruit number, and fruit diameter. The 20 cm interrow spacing showed a marked increase in marketable fruit yield by 35.96% as compared to 30 cm spacing used by farmers. Planting tomato in closer interrow spacing (60 cm) resulted in 50% yield increment than the widest (120 cm) space between rows. Interaction effects of both inter- and intrarow spacing significantly (p less then 0.
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