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RESULTS Matched data describe preoperative characteristics and perioperative outcomes in 615 patients in each group. The following significant differences were observed among the 11 outcomes that were pre-specified. Operative time tended to be longer for the RVHR group compared to the LVHR group (p less then 0.001). Length of stay differed between the two groups; while both groups had a median length of stay of 0, stay lengths tended to be longer in the LVHR group (p less then 0.001). Rates of conversion to laparotomy were fewer for the RVHR group less then 1% and 2%, respectively (p = 0.007). Through 30 days, there were fewer RVHR patient-clinic visits (p = 0.038). CONCLUSION Both RVHR and LVHR perioperative results compare favorably with each other in most measures. Differences favored RVHR in terms of shorter LOS, fewer conversions to laparotomy, and fewer postoperative clinic visits; differences favored LVHR in terms of shorter operative times.OBJECTIVE This paper aimed to discuss the scope of operation and clinical effects for locally advanced cervical cancer (LACC) after concurrent chemoradiotherapy (CCRT). METHODS We retrospectively reviewed the records of 444 patients with stages IB2-IIB cervical cancer who were divided into two groups whether or not they received CCRT before radical operation in our institute from January 2013 to December 2016. Patients' characteristics, treatments, and outcomes were analyzed. RESULTS The total efficiency (CR + PR) of the CCRT + operation group was 96.2%. Specifically, the CR rate was 9.1%, and the PR rate was 87.1%. The positive rates of cervical deep interstitial infiltration, lymphatic metastasis, and lymphangial infiltration of the operation group were significantly higher than those of the CCRT + operation group (P less then 0.05). A total of 24 and 162 patients in the CCRT + operation group and the operation group, respectively, received adjuvant therapy (P less then 0.05). The incidence rate of edema of the lower extremity, radiation enteritis, and radiocystitis after postoperative adjuvant radiotherapy in the operation group was significantly higher than that of the CCRT + operation group (P less then 0.05). The 5-year survival rates and 5-year progression-free survival (PFS) rates of the CCRT + operation and operation groups were 79.3% versus 64.0% and 68.9% versus 45.2%, respectively (P less then 0.05). CONCLUSIONS Comprehensive treatment that combines CCRT and radical operation to LACC achieves satisfying clinical effects without increasing the occurrence rate of intraoperative and postoperative complications. Moreover, such treatment can improve the 5-year PFS rate and OS rate.Many attempts have been made to classify and evaluate the nature of intelligence in humans and other species (referred to as the 'g' factor in the former and the G factor in the latter). The search for this essential structure of mental life has generated various models and definitions, yet open questions remain. Specifically, referring to intelligence by overemphasizing the anthropocentric terminology and its ethnocentric overlay is insufficient to account for individual differences and limits its generalizability in biological and cultural contexts. The present work is an attempt to adopt a different perspective on the 'g/G' factor and its measurement. We suggest that intelligence, or g/G, is reflected in a biological capacity that evolved from object manipulation in animals, into mental manipulation in humans, in response to various environmental conditions.PURPOSE To investigate the gross efficiency (GE) and delta efficiency (DE) during cycling and running in elite triathletes. METHODS Five male and five female elite triathletes completed two incremental treadmill tests with an inclination of 2.5° to determine their GE and DE during cycling and running. The speed increments between the 5-min stages were 2.4 and 0.6 km h-1 during the cycling and running tests, respectively. For each test, GE was calculated as the ratio between the mechanical work rate (MWR) and the metabolic rate (MR) at an intensity corresponding to a net increase in blood-lactate concentration of 1 mmol l-1. DE was calculated by dividing the delta increase in MWR by the delta increase in MR for each test. Pearson correlations and paired-sample t tests were used to investigate the relationships and differences, respectively. RESULTS There was a correlation between GEcycle and GErun (r = 0.66; P = 0.038; R2 = 0.44), but the correlation between DEcycle and DErun was not statistically significant (r = - 0.045; P = 0.90; R2 = 0.0020). There were differences between GEcycle and GErun (t = 80.8; P less then 0.001) as well as between DEcycle and DErun (t = 27.8; P less then 0.001). CONCLUSIONS Elite triathletes with high GE during running also have high GE during cycling, when exercising at a treadmill inclination of 2.5°. For a moderate uphill incline, elite triathletes are more energy efficient during cycling than during running, independent of work rate.PURPOSE Weight loss can result in the loss of muscle mass and bone mineral density. Obeticholic price Resistance exercise is commonly prescribed to attenuate these effects. However, the anabolic endocrine response to resistance exercise during caloric restriction has not been characterized. METHODS Participants underwent 3-day conditions of caloric restriction (15 kcal kg FFM-1) with post-exercise carbohydrate (CRC) and with post-exercise protein (CRP), and an energy balance control (40 kcal kg FFM-1) with post-exercise carbohydrate (CON). Serial blood draws were taken following five sets of five repetitions of the barbell back squat exercise on day 3 of each condition. RESULTS In CRC and CRP, respectively, growth hormone peaked at 2.6 ± 0.4 and 2.5 ± 0.9 times the peak concentrations observed during CON. Despite this, insulin-like growth factor-1 concentrations declined 18.3 ± 3.4% in CRC and 27.2 ± 3.8% in CRP, which was greater than the 7.6 ± 3.6% decline in CON, over the subsequent 24 h. Sclerostin increased over the first 2 days of each intervention by 19.
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