Notes

[Positron emission tomography together with calculated tomography/magnetic resonance image with regard to primary setting up of prostate gland cancer].
037, p=.023).

Nurse managers' roles and responsibilities continue to evolve within the complex health care system. It is important to empower nurse managers to enhance their governance practices through a well-structured programme such as coaching and mentorship to improve efficiency and effectiveness at the unit level.

Governance practices of nurse managers to create a favourable environment is essential to ensure efficiency, quality and unit outcomes. Experience as a nurse manager predicted governance practices, this implies that nurse managers should be assisted to enable them to gain experiences in governance practices.
Governance practices of nurse managers to create a favourable environment is essential to ensure efficiency, quality and unit outcomes. Experience as a nurse manager predicted governance practices, this implies that nurse managers should be assisted to enable them to gain experiences in governance practices.
We aimed to identify long-term HbA1c trajectories and examine associated characteristics in an observational, childhood-onset (<17years) type 1 diabetes cohort.

Data are from the Epidemiology of Diabetes Complications study, comprising 405 participants with ≥2 of seven possible HbA1c measurements over follow-up (1988-2013) and available DNA (baseline mean diabetes duration 21years, 53% men). HbA1c trajectories were estimated using latent class growth models. Baseline and change in participant characteristics were compared across trajectories.

Five HbA1c trajectories were identified low (51%), intermediate stable (22%), improved (19%), high stable (6%), and worsened (2%; not included in analyses). Age, diabetes duration, diabetes onset age, and sex did not differ across trajectories. Characteristics did not differ significantly between intermediate stable and low trajectories at baseline, though albumin excretion rate (AER, p=0.0002) and estimated glomerular filtration rate (eGFR, p=0.001) worsened sl against adverse metabolic effects of chronic hyperglycaemia, warranting further study.
What is the central question of this study? Does the consumption of a moderate amount of alcohol differentially impact the heart ventricles and pulmonary vasculature. What is the main finding and its importance? Moderate alcohol consumption for a short period of time impaired pulmonary vascular cellular renewal through an apoptosis resistance pattern that ultimately affected the right ventricular function and structure. These findings support the need for a deeper understanding of effects of moderate alcohol consumption on the overall cardiovascular and pulmonary systems.

Over the past decades, observational studies have supported an association between moderate alcohol consumption and a lower risk of cardiovascular disease and mortality. However, recent and more robust meta-analyses have raised concerns around the robustness of the evidence for the cardioprotective effects of alcohol. Also, studies of the functional, structural and molecular changes promoted by alcohol have focused primarily on the left ynamic recordings were performed and samples collected for further histological and molecular analysis. ETOH ingestion did not impact cardiac function. However, it caused right ventricle hypertrophy, paralleled by an activation of molecular pathways responsible for cell growth (ERK1/2, AKT), proteolysis (MURF-1) and oxidative stress (NOX4, SOD2). Furthermore, ETOH animals also presented remodelling of the pulmonary vasculature with an increase in pulmonary arteries' medial thickness, which was characterized by increased expression of apoptosis-related proteins expression (BCL-XL, BAX and caspases). Moderate alcohol consumption for a short period of time impaired the lungs and the right ventricle early, before any change could be detected on the left ventricle. Right ventricular changes might be secondary to alcohol-induced pulmonary vasculature remodelling.Kidney transplant recipients with high-risk cytomegalovirus (CMV) serostatus (seropositive donor to seronegative recipient) are at risk for late-onset CMV after cessation of antiviral prophylaxis. We report findings from a strategy of bimonthly (every 2 weeks) CMV screening for late-onset CMV. This is a single-center retrospective cohort study of 70 high-risk CMV kidney transplant recipients transplanted between June 2016 and September 2018. Patients were monitored at 6-12 months post-transplantation for late-onset CMV using bimonthly CMV nucleic acid testing (NAT). Adherence to screening and its correlation with CMV-related hospitalizations were assessed. Failure to prevent CMV-related hospitalization was classified into three categories (non-adherence to CMV testing, rapid CMV progression, and health system failure). GSK3368715 Twenty-one (30%) patients developed CMV DNAemia, of whom 10 (14%) required hospitalization. Reasons for CMV-related hospitalization despite screening were (i) screening non-adherence (50%), (ii) rapid progression (40%), and (iii) health system failure (10%). Adherence to screening was associated with lower viral counts at diagnosis (r = -.44, p = .049) and a trend towards lower risk of CMV-related hospitalization (OR 0.97 per 1% increase in adherence; 95% CI 0.94-1.00; p = .06). Bimonthly monitoring for late-onset CMV allows for early CMV detection and may lower CMV-related hospitalization.Physiologic striae atrophicae of adolescence occur mainly in healthy nonobese adolescents in association with the adolescent growth spurt. The striae typically present as erythematous, purple, or violaceous, horizontal linear plaques in the lumbar area. Occurrence of striae elsewhere on the body exclusively is rare. A PubMed search of the English literature using the key terms "physiological striae atrophicae of adolescence" OR "physiological striae atrophicae of puberty" AND "thigh" did not yield any prior report. We report a teenager with physiologic striae atrophicae of adolescence with striae restricted to the thighs.
Testing the validity and reliability of the Scale for the Environments Evaluation of Professional Nursing Practice (SEE-Nursing Practice).

The environment of professional nursing practice is key to achieve better results for clients, nurses and institutions. Therefore, instruments enabling the assessment of all its attributes are required.

Cross-sectional methodological study. The SEE-Nursing Practice, based on a previous qualitative study and literature review, was applied as a questionnaire. Exploratory and confirmatory factor analyses were used to assess construct validity.

A total of 752 nurses participated in the study. Exploratory factor analysis of the SEE-Nursing Practice led to a factor solution with 93 items and three subscales. The Structure, Process and Outcome subscales, respectively, have 43, 37 and 13 items, loaded in 6 factors, 6 factors and 2 factors and explaining 62.6%, 59.2% and 67.4% of the total variance. Cronbach's alpha of the overall scale and of the 3 subscales was greater than 0.
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