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http://www.roodandriddle.com/news/regenerative-medicine-understanding-irap-prp-and-stem-cell-therapies.html by Scott A. Hopper, DVM, MS, Diplomate ACVS
IRAP-Interlukin 1- receptor antagonist protein, used in injuries and to treat Osteoarthritis. During inflammatory conditions the body releases cyotkines such as Interlukin 1 causing damage to the joint and surrounding cartilage. IRAP works by preventing IL-1 binding to the IL-1 receptors in the joint therefore blocking the damage and inflammation caused by IL-1. IRAP involves drawing approximately 50 mls of your horse’s blood into a specialized syringe which stimulates the production of the antagonist protein. The blood is incubated in the syringe for 24 hours. After incubation the blood is placed in a centrifuge and the plasma which is rich in the antagonist protein is separated from the blood cells in multiple syringes. IRAP is then injected into the joint once every 7-10 days for 3-5 treatments. Samples are stored in a -80 C freezer until use.
     
 
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