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Proper diagnosis of biofilm attacks: present approaches used, challenges and also views money for hard times.
Exposure to information about genetics is at an all-time high, while a full understanding of the biocultural complexity of human difference is low. This paper demonstrates the value of an "anthropological approach" to enhance genetics education in biology, anthropology, and other related disciplines, when teaching about human differences such as race/ethnicity, sex/gender, and disability. As part of this approach, we challenge educators across social and natural sciences to critically examine and dismantle the tacit cultural assumptions that shape our understanding of genetics and inform the way we perceive (and teach about) human differences. It calls on educators from both social and natural science disciplines to "de-silo" their classrooms and uses examples from our biological anthropology and sociocultural anthropology classrooms, to demonstrate how educators can better contextualize the "genetics" of human difference in their own teaching. Numerous opportunities to transform our teaching exist, and we are doing a disservice to our students by not taking these critical steps.Social science inquiries of American agriculture have long recognized the inextricability of farm households and farm businesses. Efforts to train and support farmers, however, often privilege business realm indicators over social issues. Such framings implicitly position households as disconnected from farm stress or farm success. This article argues that systematically tracing the pathways between farm households and farm operations represents a potentially powerful inroad towards identifying effective support interventions. We argue childcare arrangements are an underrecognized challenge through which farm household dynamics directly influence agricultural production. We draw on interviews and focus group data with farmers in the Northeastern United States to understand how farmer-parents access and negotiate childcare. Farmer-parents value raising children on farms, but express reluctance to expect current or future labor from them. Years with young children thus represent an especially vulnerable phase during a farm's trajectory. We identify and analyze social, economic, and cognitive pathways through which childcare impacts farm operations. Social pathways include relationship tensions and gendered on-farm divisions of labor; economic pathways include farm layout and structure; cognitive pathways include how farmers think about and plan for their operations. Explicitly acknowledging such issues can better equip farmer-parents to anticipate and plan for conflicting demands on their time.Modelling and simulation (M&S) techniques are frequently used in Operations Research (OR) to aid decision-making. With growing complexity of systems to be modelled, an increasing number of studies now apply multiple M&S techniques or hybrid simulation (HS) to represent the underlying system of interest. A parallel but related theme of research is extending the HS approach to include the development of hybrid models (HM). HM extends the M&S discipline by combining theories, methods and tools from across disciplines and applying multidisciplinary, interdisciplinary and transdisciplinary solutions to practice. In the broader OR literature, there are numerous examples of cross-disciplinary approaches in model development. However, within M&S, there is limited evidence of the application of conjoined methods for building HM. Where a stream of such research does exist, the integration of approaches is mostly at a technical level. In this paper, we argue that HM requires cross-disciplinary research engagement and a conceptual framework. The framework will enable the synthesis of discipline-specific methods and techniques, further cross-disciplinary research within the M&S community, and will serve as a transcending framework for the transdisciplinary alignment of M&S research with domain knowledge, hypotheses and theories from diverse disciplines. The framework will support the development of new composable HM methods, tools and applications. Although our framework is built around M&S literature, it is generally applicable to other disciplines, especially those with a computational element. The objective is to motivate a transdisciplinarity-enabling framework that supports the collaboration of research efforts from multiple disciplines, allowing them to grow into transdisciplinary research.This work aimed at studying the potentiality of interactions between kaolinite surfaces and a protein-fragment (350-370 amino acid units) extracted from the glycoprotein E1 in the transmembrane domain (TMD) of hepatitis C virus capsid. A computational work was performed for locating the potential electrostatic interaction sites between kaolinite aluminol and siloxane surfaces and the residues of this protein-fragment ligand, monitoring the possible conformational changes. This hydrated neutralized kaolinite/protein-fragment system was simulated by means of molecular modeling based on atomistic force fields based on empirical interatomic potentials and molecular dynamic (MD) simulations. The MD calculations indicated that the studied protein-fragment interacted with the kaolinite surfaces with an exothermic process and structural distortions were observed, particularly with the hydrophilic aluminol surface by favorable adsorption energy. The viral units isolation or trapping by the adsorption on the kaolinite nanoparticles producing structural distortion of the peptide ligands could lead to the blockage of the entry on the receptor and hence a lack of viral activity would be produced. Therefore, these findings with the proposed insights could be an useful information for the next experimental and development studies in the area of discovering inhibitors of the global challenged hepatitis and other pathogenic viruses based on the phyllosilicate surface activity. These MD studies can be extended to other viruses like the COVID-19 interacting with silicate minerals surfaces.In the wake of the unprecedented global scientific output boom, are top-tier journals such as the FT50 journals following suit? If these prestigious journals consistently increase their publication volumes, will their impact factors be affected? Drawing on the Mann-Kendall trend test method, this study analysed time series trends of the FT50 journals' annual publication volumes and impact factor ratios (IFR) over a 15 year period. The results indicate that half of the FT50 journals have consistently increased their publication volumes over the years. selleck Although to increase publication volumes is riskier than to stay put, it has a significantly higher probability of increasing the IFR, and therefore keeping pace with other top journals. However, the expanding of publication volumes must be carried out cautiously, as the study also finds that growing too fast may lead to opposite effects.
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