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Neuroblastoma is a malignant embryonal tumor derived from the neural crest cells of the sympathetic nervous system. Curative therapy is challenging, especially because early-stage diagnosis in toddlers is difficult. Successful treatment of high-risk neuroblastoma is only achieved in approximately half of the cases and requires an immediate interdisciplinary approach. We present a 34-month-old toddler with swelling of the left side of the face of three days duration and a mandibular mass of unknown duration, which was diagnosed as a metastasis of a neuroblastoma. He also had metastases in the kidney, long bones and skull. Despite the poor prognosis in cases of disseminated skeletal involvement and N-myc amplification, the young patient remained free of recurrence during a follow-up period of 36 months after multidisciplinary treatment. The purpose of this case report is to increase awareness of the clinical features of neuroblastoma among pediatric dentists to support early-stage diagnosis and highlight interdisciplinary management.Purpose To investigate the extent to which parents can distinguish between their children's primary and permanent teeth in mixed dentition. Conclusion Parents do not have sufficient knowledge about their children's teeth, especially about PMFs. Parents' education on the subject is important for children's dental health.Purpose The purpose of this study was to determine which mode of education given to mothers of newborns resulted in the greatest compliance for establishing an age one dental visit and identify reasons why mothers do not bring their child for their first dental visit. Conclusion No particular maternal educational method resulted in greater compliance with scheduling an age one dental visit. Single mothers were more likely to schedule the visit. Caerulein datasheet The primary reason for not visiting was a lack of primary care provider recommendations.Purpose The purposes of this study were to (1) examine the longevity of resin crowns (RCs), pre-veneered stainless steel crowns (PVSSCs), and stainless steel crowns (SSCs) in primary maxillary incisors in a nationwide sample of private insurance claims; and (2) explore whether longer survival rates are related to the type of treating practitioner. Conclusion SSCs and PVSSCs had greater longevity than resin crowns. The survival rate after six years was higher than 90 percent for all types of restorations. Teeth restored with SSCs lasted longer when placed by pediatric dentists than those placed by general dentists.Purpose The purposes of this study were to (1) describe patients preplanned for admission to the hospital after dental treatment under general anesthesia (GA) and compare patients who were admitted to those not admitted; (2) describe patients with unplanned admission to the hospital after dental treatment under GA; and (3) refine the criteria used for preplanning patients for admission. Conclusion Among patients preplanned for admission to the hospital following dental surgery, 62 percent were admitted; these patients received significantly more intravenous fluids, antiemetic and/or analgesic medications, and airway support than patients not admitted.Purpose To evaluate the perception of caregivers of individuals with Down syndrome (DS) regarding the impact of oral conditions on their children's oral health-related quality of life (OHRQoL) and compare with the perception of caregivers of children without DS. Conclusion Caregivers of individuals with DS presented more negative perceptions of the impact of oral conditions on their children's OHRQoL. Clinical consequences of untreated dental caries and visible plaque were the determining factors with the greatest impact on the perception of their children's OHRQoL.Purpose To evaluate the satisfaction of pediatric dentists in associateship agreements. Associateship agreements were deemed satisfactory if a dentist would recommend the employment experience to a colleague. Conclusion Nearly two-thirds of pediatric dentists who worked as an associate would recommend the experience to a colleague. Many dentists viewed these as positive career opportunities, even if the associateship did not culminate in buy-in or buy-out.
Epinephrine is the first-line therapy for patients with anaphylaxis, and intramuscular (IM) delivery is shownto be superior to subcutaneous (SC) delivery. There currently is no consensus on the ideal body position for epinephrine autoinjector (EAI) administration.
We designed this study to investigate whether SC tissue depth (SCTD) is affected by body position (e.g., standing, sitting, supine), which can potentially impact delivery of EAI into the IM space.
Volunteer adults (ages >/= 18 years) from a military medical treatment facility in the United States were recruitedto participate in this study. SCTD of the vastus lateralis was measured via ultrasound at standing, sitting, and supine bodypositions. Subjects' age, sex, and body mass index (BMI) were collected. Statistical analysis was performed to compare averageSCTD between body positions, sex, and BMI.
An analysis of variance of 51 participants (33 men and 18 women) did not reveal statistically significant differencein SCTD among standing, sitting, and supine body positions. It did show a significantly greater SCTD in women than in men (2.72 +/- 1.36 cm versus 1.10 +/- 0.38 cm; p < 0.001). There was no significant association observed between BMI and SCTD in this study.
Body position did not seem to significantly change the distance between skin and thigh muscle in adults. Thiswould suggest that there might not be an ideal body position for EAI administration. Therefore, in case of anaphylaxis, promptadministration of epinephrine is recommended at any position.
Body position did not seem to significantly change the distance between skin and thigh muscle in adults. Thiswould suggest that there might not be an ideal body position for EAI administration. Therefore, in case of anaphylaxis, promptadministration of epinephrine is recommended at any position.Background Hereditary angioedema (HAE) is a rare genetic disorder clinically characterized by recurrent attacks of subcutaneous and mucosal swelling. Attenuated androgens have been a prophylactic treatment option to reduce the frequency of HAE attacks for > 4 decades. However, the advent of effective on-demand treatments and highly effective, more tolerable, long-term prophylactic therapies has led to a decline in the use of attenuated androgens for the management of HAE in regions where newer therapies are available. A consensus about the best approach for discontinuing or tapering off attenuated androgen therapy does not exist. Objective To develop a consensus on androgen tapering for patients with HAE. Methods We sent an open-ended survey about androgen tapering to 21 physicians who treat HAE, 12 of whom responded. We reviewed the collective experience of the participating physicians in combination with results from a literature review on the topic. Results The survey and literature review underscored potential concerns related to rapid androgen withdrawal in patients with HAE, including physician and patient concerns that the frequency and severity of attacks would abruptly worsen.
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