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Gender disparity exists among authors of the oncology literature.
To quantify trends in authorship by gender within a comprehensive data set of Medline-indexed oncology articles in medical journals with high impact factors.
This cross-sectional study used Medline citations to examine archives of research journals from 3 disciplines in the oncology literature. Authors from all oncology-related articles with Medical Subject Headings terms assigned from 2002 to 2018 from 13 general oncology/medicine, radiation oncology, and surgical journals were included for analysis, encompassing clinical trials, observational studies (excluding case reports), reviews, systematic reviews, meta-analyses, and all other published articles. Data were analyzed between April and May 2020.
Authors were assigned genders based on societal naming norms via third-party gender identification service Gender-API.com. This assignment was internally validated based on manually obtained publicly available data on the internet.
Trend for radiation oncology or surgical oncology journals.
This cross-sectional study found that female authorship in oncology research literature has increased. However, there remains a dearth of female senior authors, and the overall rise in female authorship has not kept up with the rise in female oncology faculty.
This cross-sectional study found that female authorship in oncology research literature has increased. However, there remains a dearth of female senior authors, and the overall rise in female authorship has not kept up with the rise in female oncology faculty.
Knowledge of differences in mild traumatic brain injury (mTBI) recovery by sex and age may inform individualized treatment of these patients.
To identify sex-related differences in symptom recovery from mTBI; secondarily, to explore age differences within women, who demonstrate poorer outcomes after TBI.
The prospective cohort study Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) recruited 2000 patients with mTBI from February 26, 2014, to July 3, 2018, and 299 patients with orthopedic trauma (who served as controls) from January 26, 2016, to July 27, 2018. Patients were recruited from 18 level I trauma centers and followed up for 12 months. Data were analyzed from August 19, 2020, to March 3, 2021.
Patients with mTBI (defined by a Glasgow Coma Scale score of 13-15) triaged to head computed tomography in 24 hours or less; patients with orthopedic trauma served as controls.
Measured outcomes included (1) the Rivermead Post Concussion Symptoms Questionnaire (RPQ), a .
This study found that women were more vulnerable than men to persistent mTBI-related cognitive and somatic symptoms, whereas no sex difference in symptom burden was seen after orthopedic injury. Postconcussion symptoms were also worse in women aged 35 to 49 years than in younger and older women, but further investigation is needed to corroborate these findings and to identify the mechanisms involved. Results suggest that individualized clinical management of mTBI should consider sex and age, as some women are especially predisposed to chronic postconcussion symptoms even 12 months after injury.
There is widespread consensus on the challenges to meeting the end-of-life wishes of decedents in the US. However, there is broad but not always recognized success in meeting wishes among decedents 65 years and older.
To assess how well end-of-life wishes of decedents 65 years and older are met in the last year of life.
This quality improvement study involved 3 planned samples of family members or informants identified as the primary contact in the medical record of Kaiser Permanente Southern California decedents. The first sample was 715 decedents, 65 years or older, who died between April 1 and May 31, 2017. The second was a high-cost sample of 332 decedents, 65 years or older, who died between June 1, 2016, and May 31, 2017, and whose costs in the last year of life were in the top 10% of the costs of all decedents. The third was a lower-cost sample with 655 decedents whose costs were not in the top 10%. The survey was fielded between December 19, 2017, and February 8, 2018.
Meeting end-of-life wishthern California cohort, a large proportion of decedents 65 years and older had end-of-life discussions and documentation, had their wishes met, and received the amount of care they thought appropriate.
In this Kaiser Permanente Southern California cohort, a large proportion of decedents 65 years and older had end-of-life discussions and documentation, had their wishes met, and received the amount of care they thought appropriate.
There are concerns that the use of water pipes to consume cannabis is associated with increased risks of engaging in more addictive behaviors.
To examine whether consuming cannabis with a water pipe was associated with later consumption of other illicit drugs compared with not using a water pipe.
The Cohort Study on Substance Use Risk Factors (C-SURF) was a population-based study, recruiting 5987 Swiss men aged 18 to 25 years from 3 of 6 Swiss Armed Forces recruitment centers (response rate 79.2%). The baseline assessment (t0) was done from 2010 to 2012, first follow-up (t1) from 2012 to 2014, and second follow-up (t2) from 2016 to 2018. see more Our sample included men who participated in both t0 and t2 assessments and used cannabis but no other illicit drugs at t0. Data analysis was performed from July 2020 to January 2021.
Cannabis use frequency and route of administration from self-administered questionnaires completed at t0 and t2.
Outcome measures were initiation of illicit drug use and cannabis use dife, particularly middle-stage illicit drugs. Preventive programs must focus on the potential of later harm to cannabis users who use water pipes but have not yet started taking other illicit drugs.
This cohort study's results suggest that, among Swiss young men, water pipe use is associated with other illicit drug use later in life, particularly middle-stage illicit drugs. Preventive programs must focus on the potential of later harm to cannabis users who use water pipes but have not yet started taking other illicit drugs.
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