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11; p=0.03) in the pooled analysis of studies using zinc alone and in combination with other micronutrients. One study demonstrated a significant reduction of HbA1c by 0.5% with combined supplementation, while another reported a significant reduction in CRP with zinc supplementation. When all trials were considered, TC, HDL-c and HOMA-β showed significant improvement. Zinc supplementation significantly improved the zinc status from baseline.
Zinc supplementation demonstrated beneficial effects on glycaemic and lipid parameters in individuals with pre-diabetes. It may have the potential to reduce the prevalence of pre-diabetes and control associated morbidity and mortality.
Zinc supplementation demonstrated beneficial effects on glycaemic and lipid parameters in individuals with pre-diabetes. It may have the potential to reduce the prevalence of pre-diabetes and control associated morbidity and mortality.
Earlier or delayed puberty can be determined by numerous causes, but the exact mechanisms are not fully known. Anyway, those may be independent from the hypothalamicpituitary-gonadal axis involvement. Certainly, obesity is one of the main factors. In fact, obesity and infertility are strongly linked. For this reason, we want to analyse the relationship between puberty and obesity and give an updated state-of-the-art starting by discussing a 14-year-old obese boy's clinical case.
Literature data are conflicting. Main criticisms are related to study design and evaluation criteria. Indeed, examined populations are not homogeneous by age, Tanner stage and BMI classification. The obesity epidemic is involved in earlier puberty, and puberty seems to be anticipated in all BMI groups. Very few studies evaluate the level of adiposity in the diagnosis of obesity. However, the role of the adipose tissue is crucial for hormone synthesis and regulation. Therefore, fat mass age-related and not simply BMI has to be considered by clinicians for appropriate diagnosis.
Regarding the clinical case, in three months our patient recovered delayed pubertal development following an anti-inflammatory and antioxidant Mediterranean Diet. Loss of weight, as in decrease of fat mass but saving of lean mass, increased testicular volume and testosterone levels occurred.
Puberty depends on several factors, including obesity. Further studies are needed to evaluate age groups, Tanner stage, diet and lifestyle, ethnicity and above all the fat/lean mass ratio. Lack of adequate tools could hinder a clinician's ability to recognize when or if therapeutic intervention is needed.
Puberty depends on several factors, including obesity. Further studies are needed to evaluate age groups, Tanner stage, diet and lifestyle, ethnicity and above all the fat/lean mass ratio. Lack of adequate tools could hinder a clinician's ability to recognize when or if therapeutic intervention is needed.
The prognostic role exerted by the concurrent presence of sarcopenia and obesity after hip fracture has not been elucidated.
To assess the effect of sarcopenic obesity on ability to function in women with subacute hip fracture.
Short-term prospective study.
Rehabilitation hospital.
Women with subacute hip fracture.
At admission, grip strength, by a Jamar dynamometer, and body composition by dual-energy x-ray absorptiometry were assessed. Sarcopenia was defined according to the criteria released by the European Working Group for Sarcopenia in Older People in 2019, with both grip strength < 16kg and appendicular lean mass (aLM) < 15kg. Alternatively, aLM/(height)2 < 5.5kg/m2 was substituted for aLM < 15kg to confirm sarcopenia in the women with grip strength < 16kg. Obesity was diagnosed with fat mass exceeding 40% of total body mass. selleck Function was assessed by the Barthel index.
We assessed 183 of 200 women. Sarcopenic women had lower Barthel index scores assessed at the end of subac fracture, sarcopenia but not obesity should be assessed to contribute to the prediction of the short-term functional outcome.
In women with subacute hip fracture, sarcopenia but not obesity should be assessed to contribute to the prediction of the short-term functional outcome.
Therapeutic exercise is highly recommended for the management of non-specific neck pain and has shown promising results combined with interferential current therapy. Yet, the clinical relevance of the pooled effect of these approaches remains uncertain.
To investigate the immediate clinical effect size of combining therapeutic exercise and interferential therapy, compared with the isolated use of therapeutic exercise, in adults with chronic non-specific neck pain.
Randomized, single-blinded, controlled, superiority trial.
Outpatients, primary care center.
Forty-nine adults with chronic non-specific neck pain.
Participants with neck pain (grades I or II) lasting for more than 12 weeks were allocated to a therapeutic exercise plus interferential currents group (n = 25) or to a therapeutic exercise only group (n = 24). All individuals underwent treatment 5 times a week for 2 weeks. The primary outcome was current neck pain intensity (11-point numeric pain rating scale). Secondary outcomes included netion of patients with non-specific neck pain. This is the first study on this topic reporting findings in terms of clinical relevance, which is key to transfer research evidence into practice.
Our results suggest that this multimodal intervention can be a useful strategy for rehabilitation of patients with non-specific neck pain. This is the first study on this topic reporting findings in terms of clinical relevance, which is key to transfer research evidence into practice.
Fibromyalgia (FM) is a pathology that causes physical, psychological, and social problems. For this reason, it requires treatment that involves all of these elements. The main of study is to examine multidisciplinary rehabilitation treatment (MRT) in fibromyalgia and to identify healthcare approaches developing effective MRT tools for the treatment of FM.
In this systematic review, we searched the following databases CINAHL, PubMed, Scopus, Cuidatge, Cuiden, ENFISPO, IBEC and IME.
Of 356 articles found we selected 13 to analyze and summarize. We created 4 different categories (1) multidisciplinary rehabilitation treatment focusing on health education and cognitive behavioral therapy (CBT), (2) multidisciplinary rehabilitation treatment that includes dietetics, (3) multidisciplinary rehabilitation treatment adapted to the patients' characteristics and (4) multidisciplinary rehabilitation treatment based on physical exercise.
This review identifies the most effective treatments that may be usefully applied in many different rehabilitation contexts.
Homepage: https://www.selleckchem.com/products/jke-1674.html
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