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Impact regarding aerobic fitness exercise upon medical along with magnetic resonance image biomarkers within persons using multiple sclerosis: An exploratory randomized controlled demo.
Plants play a vital role in the general wellbeing of an individual. Globally plants are habitually used by the people for the treatment and prevention of various ailments. There is an increased attempt made from ancient days to prevent the disease occurrence rather than to treat it. Through the development of modern scientific procedures, it is now identified that the usage of plants in different forms promotes the health of the patient. Oral and dental hygiene is the primary factor of a human being to lead a healthy life. Poor diet, nutrition and improper hygienic practices lead to teeth and gum diseases, dental cavities and plaque etc., Use of herbal extracts and their products in day-to-day life is a promising and interesting alternative to synthetic compounds to control oral diseases. The present review summarizes the usage of medicinal plants in the treatment and prevention of oral and dental diseases in different aspects. Copyright© Bentham Science Publishers; For any queries, please email at [email protected] are habitats with very specific environmental conditions, often substantially differing from their natural surroundings. Roadside trees provide home for many floral and faunal species and have many environmental benefits including removing air pollutants, supporting wildlife etc. Many medicinal plants including road side trees have been discovered and traditionally they are being used for treating many kinds of diseases. Phytochemicals are chemical compounds that are usually secreted by the plants for performing functions like defense against insects, fungi, diseases and animals that feed on them. These phytochemicals with potential biological activities have been identified from various plant species, yet many of the medicinal potency of the plants remain unexplored. Modern knowledge on the potential value of the medicinal plants has made it possible for the researchers and medical practitioners to use the plant derived products in modern medicine with diminished adverse effects. Road side plants in Tamilnadu also possess many such pharmacologically active compounds with therapeutical actions. Copyright© Bentham Science Publishers; For any queries, please email at [email protected] Isolation and characterization of Bioactive Metabolite from Bacillus safensis VRKK2 for controlling Bacterial blight disease in Cowpea. https://www.selleckchem.com/products/art0380.html OBJECTIVES The primary objective of the study was to describe the biocontrol potential of Bacillus safensis VRKK2 against Bacterial blight disease in Cowpea and improve the yield of the cowpea plant. METHODS Primarily the rhizobacteria isolated from cowpea Rhizosphere screened for the plant growth promoting traits and further Bioactive Metabolite extracted and purified from PGPR and identified using standard analytical techniques. The purified bioactive metabolite efficacy analyzed in In vitro and In vivo study in host plants. RESULTS From the initial screening the strain Bacillus safensis VRKK2 found to be potential organism of their IAA concentration found to be maximum of 171.2 µg/ml, phosphate solubilization efficiency found to be maximum of 155 SE also positive for siderophore production, nitrogen fixation assay and ammonia production. Phylogenetic tree results with 99% similarity. Extracted compound showed spots on TLC visualized by UV illuminator, fluorescent band was observed at 0.47 Rf value and tested for their pathogen suppression efficiency against Xanthomonas campestris, purified fractions showed 11mm and 15mm of zone of inhibition against test pathogen and the overall disease severity percentage is 34.75 %. CONCLUSION This study specifies that the isolated PGPR Bacillus safensis VRKK2 found to be better biocontrol agent against bacterial blight disease in cowpea. Copyright© Bentham Science Publishers; For any queries, please email at [email protected] Substantial evidences support the hypothesis that the epicardium has a role in cardiac repair and regeneration in part providing, by epithelial to mesenchymal transition (EMT), progenitor cells that differentiate into cardiac cell types and in part releasing paracrine factors that contribute to cardiac repair. Beside cell contribution, a significant paracrine communication occurs between the epicardium and the myocardium that improves the whole regenerative response. Signaling pathways underlying this communication are multiple as well as soluble factors involved in cardiac repair and secreted both by myocardial and epicardial cells. Most recently, extracellular vesicles, i.e. exosomes, that accumulate in the pericardial fluid (PF) and are able to transport bioactive molecules (cytosolic proteins, mRNAs, miRNAs and other non-coding RNAs), have been also identified as potential mediators of epicardial-mediated repair following myocardial injury. CONCLUSIONS This mini review provides an overview of the epicardial-myocardial signaling in regulating cardiac repair in ischemic heart diseases. Indeed, a detailed understanding of the crosstalk between myocardial and epicardial cells and how paracrine mechanisms are involved in the context of ischemic heart diseases would be of tremendous help in developing novel therapeutic approaches to promote cardiomyocytes survival and heart regeneration following myocardial infarction (MI). Copyright© Bentham Science Publishers; For any queries, please email at [email protected] Liver cancer is otherwise known as Hepatic cancer which originated from the liver. Hepatocellular carcinoma (HCC) is the common primary Liver cancer and is one of the emerging problems worldwide. Very few treatments are available to treat HCC, because the molecular mechanism and other HCC mechanisms are still unclear. Cyclooxygenase 2 (COX-2), one of the most promising targets for Hepatocellular Carcinoma and it is one of the dimeric enzymes which convert Arachidonic acid into Prostaglandin H2 in the step of Prostaglandin biosynthesis. Several, natural bioactive compounds involved in the treatment of various types of cancer. Tangeretin, one of the natural polymethoxyflavone which is present in the peel of citrus fruits and it also acts as an Anti-oxidant modulator and Anti-cancerous. METHODS Computational approaches like Molecular docking and Molecular dynamics was performed to identify the potential inhibitor for Hepatocellular Carcinoma. OBJECTIVES The main objective of this study is to find a suitable inhibitor for Hepatocellular Carcinoma.
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