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A new Standard protocol to be able to Organized Radiographic Review associated with Main Complete Joint Arthroplasty.
Goat milk significantly increased the numbers of Bifidobacterium spp. and Lactobacillus spp. and decreased the numbers of Clostridium perfringens in the caecum and colon of rats treated with amoxicillin. Whereas, rats fed cow milk had higher Lactobacillus spp. and lower C. perfringens in the gut. Caecal and colonic SCFAs (acetic, butyric and propionic) concentrations differed significantly between rats fed cow and goat milk diets. Overall, goat and cow milk varied in their effects on the immature gut following antibiotic-induced dysbiosis in a rat model.The exploration of novel intermetallic compounds is of great significance for basic research and practical application. Considering the interesting and diverse attributes of Na and Au, their large electronegative difference, and the unresolved high-pressure Na-Au structures, first-principles swarm-intelligence structural search calculations are employed to explore the potential Na-Au compounds at high pressures. Besides reproducing the known Na-Au compounds, eleven new phases are disclosed, exhibiting several unprecedented Au atomic arrangements, such as rectangular ladder, layer formed by edge-sharing squares, hexahedron framework, and diamond-like skeleton, enriching the understanding of Au chemistry. Moreover, the coordination number of Au can be effectively modulated by controlling Na composition. In the Na-rich compounds (Na4Au, Na5Au, and Na6Au), Au shows a formal charge beyond -2, acting as a 6p-block element, originating from pressure-induced unusual Na 3s or 3p → Au 6p charge transfer. These compounds are metallic, but not superconductive. https://www.selleckchem.com/products/beta-lapachone.html Moreover, the good agreement between the experimental XRD patterns and the simulated ones allows us to assign the predicted P6/mmm Na2Au and Fm3[combining macron]m Na3Au as the experimental structures at 59.6 GPa. Our work indicates that the modulation of pressure and chemical composition is a useful way to stabilize novel intermetallic compounds.In this paper, the electronic structure and transport properties of a ductile thermoelectric material α-Ag2S are examined using first-principles calculations combined with the Boltzmann transport equation within a constant relaxation-time approximation. The use of the exchange-correlation functional SCAN + rVV10 successfully describes the geometric and electronic structure of α-Ag2S with a direct bandgap value of 0.99 eV, which is consistent with the previous experimental observations. Based on the calculations of the formation energy of typical intrinsic defects, it is found that intrinsic defect formation greatly affects the conductivity of the system where silver vacancy and interstitial silver act as p-type and n-type defects, respectively. Large Seebeck coefficients at room-temperature, of around -760 μV K-1 for n-type and 1400 μV K-1 for p-type, are realized. It is also suggested that the doping of fully filled d-block elements such as Cu and Au not only maintained the Seebeck coefficients at high values but also improved electrical conductivity by more than 1.4 times, leading to the improvement of the power factor by up to 40% compared to the non-doped sample at low carrier concentration.We report a joint experimental and theoretical study of the low-pressure phase of α'-Ga2S3 under compression. Theoretical ab initio calculations have been compared to X-ray diffraction and Raman scattering measurements under high pressure carried out up to 17.5 and 16.1 GPa, respectively. In addition, we report Raman scattering measurements of α'-Ga2S3 at high temperature that have allowed us to study its anharmonic properties. To understand better the compression of this compound, we have evaluated the topological properties of the electron density, the electron localization function, and the electronic properties as a function of pressure. As a result, we shed light on the role of the Ga-S bonds, the van der Waals interactions inside the channels of the crystalline structure, and the single and double lone electron pairs of the sulphur atoms in the anisotropic compression of α'-Ga2S3. We found that the structural channels are responsible for the anisotropic properties of α'-Ga2S3 and the A'(6) phonon, known as the breathing mode and associated with these channels, exhibits the highest anharmonic behaviour. Finally, we report calculations of the electronic band structure of α'-Ga2S3 at different pressures and find a nonlinear pressure behaviour of the direct band gap and a pressure-induced direct-to-indirect band gap crossover that is similar to the behaviour previously reported in other ordered-vacancy compounds, including β-Ga2Se3. The importance of the single and, more specially, the double lone electron pairs of sulphur in the pressure dependence of the topmost valence band of α'-Ga2S3 is stressed.The electronic transport properties of in-plane graphene/MoS2/graphene heterojunctions are studied using density functional theory and the nonequilibrium Green's function method. It is found that different covalent bond connections cause different electron distributions, such as accumulation or depletion, on the contact surface. The C-S structure exhibits more electron accumulation and depletion, indicating that the electrons can easily transfer from MoS2 to graphene. Since the three structures all form covalent or ionic bonds, the tunneling barrier for carriers is very small. The C-S structure exhibits a smaller p-type Schottky barrier, indicating that it has better transport properties than the other two structures. We found that the effective doping method can reduce the Schottky-barrier height (SBH), resulting in smaller contact resistance. Thus, the current-voltage curves of the undoped and doped C-S structures exhibit rectification and approximately linear characteristics under a given bias, which agrees with experimental reports. These results provide insight for designing high-performance devices.The Pt(iv) complexes based on (SP-4-2)-dichlorido(cyclohexane-1,4-diamine)platinum(ii) (kiteplatin) and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid (POA) were investigated. Since POA contains a chiral carbon, all the possible Pt(iv) isomers were prepared and characterized, and their antiproliferative activity on six cancer cell lines was compared with that of the corresponding Pt(iv) complexes containing the cyclohexane-1R,2R-diamine equatorial ligand. To justify the very good antiproliferative activity (nanomolar IC50), the polarity, lipophilicity, permeability, and cell accumulation of the complexes were studied. Overall, the two series of Pt(iv) complexes showed similar cell penetration properties, being significantly better than that of the Pt(ii) reference compounds. Finally, a representative compound of the whole set of complexes (i.e., that based on cyclohexane-1R,2R-diamine and racemic POA) was tested in vivo on mice bearing Lewis lung carcinoma, showing good tumor growth inhibition with negligible body weight loss.
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